Best TWAS P=2.05e-09 · Best GWAS P=1.31e-08 conditioned to 0.161
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | METTL9 | 0.12 | 0.09 | lasso | 5 | 0.06 | 2.0e-05 | -5.4 | -5.6 | 1.8e-08 | -0.77 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Lung | CTB-31N19.3 | 0.15 | 0.09 | lasso | 2 | 0.07 | 4.4e-06 | -5.4 | -5.4 | 6.9e-08 | -0.64 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Whole Blood | METTL9 | 0.07 | 0.05 | lasso | 4 | 0.05 | 1.8e-05 | -5.4 | -6.0 | 2.1e-09 | -0.81 | 0.01 | 0.99 | TRUE |
| 4 | NTR | Blood | IGSF6 | 0.02 | 0.01 | lasso | 3 | 0.01 | 6.0e-05 | -5.5 | -5.6 | 2.6e-08 | -0.67 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SLC7A5P2 | 0.04 | 0.00 | blup | 6 | 0.01 | 2.4e-02 | -4.6 | 5.4 | 5.9e-08 | 0.72 | 0.00 | 0.28 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | OTOA | 0.03 | 0.02 | blup | 37 | 0.01 | 1.1e-02 | 5.7 | -5.9 | 4.0e-09 | -0.87 | 0.00 | 0.96 | FALSE |