Best TWAS P=3.45e-08 · Best GWAS P=7.83e-08 conditioned to 0.192
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | B3GALTL | 0.37 | 0.17 | enet | 29 | 0.30 | 4.3e-17 | -4.9 | -5.1 | 2.9e-07 | 0.68 | 0.07 | 0.92 | FALSE |
2 | GTEx | Brain Cortex | B3GALTL | 0.25 | 0.13 | lasso | 8 | 0.15 | 5.4e-05 | -5.3 | -5.2 | 2.0e-07 | 0.93 | 0.02 | 0.96 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | B3GALTL | 0.32 | 0.29 | enet | 19 | 0.29 | 7.6e-22 | -4.8 | -5.1 | 3.1e-07 | 0.84 | 0.15 | 0.84 | FALSE |
4 | GTEx | Colon Transverse | B3GALTL | 0.18 | 0.09 | lasso | 4 | 0.07 | 3.4e-04 | -5.1 | -5.3 | 1.2e-07 | 0.96 | 0.03 | 0.95 | FALSE |
5 | GTEx | Esophagus Muscularis | B3GALTL | 0.23 | 0.10 | lasso | 6 | 0.11 | 3.0e-07 | -3.7 | -5.3 | 1.1e-07 | 0.84 | 0.05 | 0.94 | FALSE |
6 | GTEx | Skin Sun Exposed Lower leg | B3GALTL | 0.15 | 0.02 | enet | 9 | 0.02 | 1.0e-02 | -4.8 | -5.2 | 1.9e-07 | 0.79 | 0.07 | 0.92 | FALSE |
7 | GTEx | Testis | B3GALTL | 0.29 | 0.15 | lasso | 6 | 0.18 | 2.6e-08 | -5.3 | -5.5 | 3.4e-08 | 0.85 | 0.03 | 0.97 | TRUE |
8 | GTEx | Thyroid | B3GALTL | 0.25 | 0.27 | lasso | 5 | 0.24 | 9.9e-19 | -5.3 | -5.2 | 1.8e-07 | 0.99 | 0.01 | 0.99 | FALSE |
9 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | B3GALTL | 0.06 | 0.01 | blup | 104 | 0.02 | 1.6e-02 | -5.0 | -5.2 | 2.4e-07 | 0.89 | 0.02 | 0.91 | FALSE |
10 | The Cancer Genome Atlas | Breast Invasive Carcinoma | B3GALTL | 0.02 | 0.00 | blup | 105 | 0.01 | 1.9e-03 | -3.7 | -5.4 | 8.2e-08 | 0.79 | 0.05 | 0.73 | FALSE |
11 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | B3GALTL | 0.03 | 0.02 | blup | 105 | 0.02 | 2.0e-03 | -4.9 | -5.2 | 2.4e-07 | 0.86 | 0.04 | 0.92 | FALSE |
12 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | B3GALTL | 0.14 | 0.12 | blup | 104 | 0.15 | 5.2e-07 | -5.3 | -5.3 | 1.3e-07 | 0.91 | 0.02 | 0.98 | FALSE |
13 | The Cancer Genome Atlas | Prostate Adenocarcinoma | B3GALTL | 0.10 | 0.08 | blup | 104 | 0.12 | 3.3e-12 | -5.0 | -5.1 | 2.8e-07 | 0.91 | 0.04 | 0.96 | FALSE |
14 | The Cancer Genome Atlas | Thyroid Carcinoma | B3GALTL | 0.14 | 0.17 | blup | 105 | 0.20 | 2.2e-19 | -5.1 | -5.4 | 5.1e-08 | 0.93 | 0.01 | 0.99 | FALSE |