[Hub]/) : Traits : Body mass index (BMI) : ← →

chr14:71,712,035-74,192,791

Best TWAS P=7.33e-11 · Best GWAS P=3.69e-08 conditioned to 0.0182

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RGS6 0.07 0.02 bslmm 888 0.01 2.0e-02 -1.5 5.7 1.6e-08 -0.21 0.13 0.03 TRUE
2 GTEx Adipose Subcutaneous DCAF4 0.20 0.05 lasso 7 0.18 1.1e-14 3.9 5.3 1.2e-07 -0.66 0.09 0.90 FALSE
3 GTEx Adipose Visceral Omentum DCAF4 0.23 0.07 enet 30 0.13 4.3e-07 3.7 5.7 1.5e-08 -0.48 0.40 0.52 FALSE
4 GTEx Adipose Visceral Omentum RP11-109N23.6 0.14 0.11 enet 15 0.13 2.2e-07 -5.5 6.4 1.5e-10 -0.81 0.01 0.99 TRUE
5 GTEx Breast Mammary Tissue DCAF4 0.24 0.10 lasso 6 0.18 1.2e-09 3.9 5.8 5.9e-09 -0.63 0.46 0.47 FALSE
6 GTEx Breast Mammary Tissue (Female) RP11-109N23.6 0.18 -0.01 lasso 7 0.00 3.9e-01 -3.9 5.8 7.6e-09 -0.67 0.05 0.56 FALSE
7 GTEx Colon Sigmoid DCAF4 0.30 0.10 lasso 9 0.11 1.3e-04 4.4 5.4 6.3e-08 -0.39 0.10 0.37 FALSE
8 GTEx Esophagus Gastroesophageal Junction DCAF4 0.18 0.01 enet 10 0.06 3.0e-03 4.4 6.5 7.3e-11 -0.46 0.08 0.42 TRUE
9 GTEx Esophagus Mucosa DCAF4 0.30 0.19 enet 35 0.23 1.3e-15 4.4 5.7 8.9e-09 -0.51 0.54 0.43 FALSE
10 GTEx Esophagus Mucosa ZFYVE1 0.10 0.00 lasso 7 0.00 2.0e-01 4.4 6.2 4.8e-10 -0.67 0.05 0.83 FALSE
11 GTEx Spleen DCAF4 0.47 0.12 enet 10 0.19 1.5e-05 3.9 5.9 3.2e-09 -0.55 0.20 0.70 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DCAF4 0.04 0.02 blup 83 0.03 1.2e-04 3.4 5.3 9.5e-08 -0.64 0.19 0.59 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma DPF3 0.10 0.02 blup 210 0.07 1.9e-07 -4.2 -5.5 3.7e-08 0.62 0.13 0.85 FALSE