Best TWAS P=4.33e-08 · Best GWAS P=2.46e-07 conditioned to 0.338
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | ADORA2B | 0.23 | 0.27 | enet | 10 | 0.24 | 7.4e-07 | -5.0 | -5.3 | 1.3e-07 | 0.97 | 0.05 | 0.94 | FALSE |
| 2 | GTEx | Whole Blood | ADORA2B | 0.08 | 0.00 | lasso | 5 | 0.00 | 2.5e-01 | -4.8 | -5.5 | 4.3e-08 | 0.85 | 0.05 | 0.61 | TRUE |
| 3 | YFS | Blood | PIGL | 0.02 | 0.02 | blup | 279 | 0.02 | 1.5e-06 | -3.2 | -5.1 | 3.0e-07 | 0.88 | 0.22 | 0.77 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TTC19 | 0.03 | 0.03 | enet | 8 | 0.03 | 2.0e-04 | -5.0 | 5.2 | 2.3e-07 | -0.97 | 0.03 | 0.96 | FALSE |