Best TWAS P=6.98e-14 · Best GWAS P=2.07e-15 conditioned to 0.0216
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6 | GTEx | Thyroid | KCNJ12 | 0.36 | 0.23 | lasso | 5 | 0.25 | 2.9e-19 | -5.9 | -7.5 | 7.0e-14 | 0.81 | 0.66 | 0.34 | TRUE |
| 1 | GTEx | Esophagus Mucosa | TMEM11 | 0.20 | 0.00 | lasso | 7 | 0.01 | 9.3e-02 | 4.0 | 5.4 | 7.1e-08 | -0.10 | 0.05 | 0.45 | TRUE |
| 5 | GTEx | Thyroid | DHRS7B | 0.17 | 0.02 | enet | 22 | 0.11 | 1.2e-08 | -4.7 | -6.2 | 7.2e-10 | 0.26 | 0.70 | 0.18 | FALSE |
| 2 | GTEx | Lung | C17orf103 | 0.08 | 0.01 | enet | 11 | 0.04 | 6.6e-04 | 5.3 | 6.0 | 1.6e-09 | -0.53 | 0.18 | 0.40 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | C17orf103 | 0.11 | 0.02 | enet | 15 | 0.07 | 1.0e-06 | 2.5 | 5.5 | 4.0e-08 | -0.33 | 0.28 | 0.33 | FALSE |
| 4 | GTEx | Testis | C17orf103 | 0.15 | 0.21 | enet | 4 | 0.19 | 7.1e-09 | -4.9 | 5.4 | 6.5e-08 | -0.33 | 0.96 | 0.02 | FALSE |