[Hub]/) : Traits : Body mass index (BMI) :

chr17:4,041,725-6,068,117

Best TWAS P=2.54e-10 · Best GWAS P=4.08e-09 conditioned to 0.000667

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RABEP1 0.13 0.03 lasso 13 0.02 7.2e-02 -4.0 -5.2 1.7e-07 -0.80 0.04 0.83 FALSE
2 GTEx Brain Putamen basal ganglia AC012146.7 0.30 0.03 enet 23 0.03 7.6e-02 4.8 -6.3 2.5e-10 -0.45 0.08 0.28 TRUE
3 GTEx Cells Transformed fibroblasts GP1BA 0.22 0.10 enet 9 0.18 3.1e-13 5.7 5.1 2.9e-07 0.26 0.03 0.97 FALSE
4 GTEx Colon Sigmoid GP1BA 0.25 0.17 lasso 4 0.12 3.6e-05 5.0 5.2 2.5e-07 0.28 0.18 0.34 FALSE
5 GTEx Esophagus Gastroesophageal Junction DHX33 0.12 0.08 lasso 5 0.07 1.8e-03 5.8 -5.6 1.8e-08 -0.96 0.02 0.96 FALSE
6 GTEx Esophagus Gastroesophageal Junction RABEP1 0.19 -0.01 lasso 13 0.00 4.2e-01 4.6 -5.3 9.3e-08 -0.82 0.04 0.79 FALSE
7 GTEx Esophagus Gastroesophageal Junction GP1BA 0.35 0.16 lasso 11 0.18 5.9e-07 4.5 6.0 2.0e-09 0.56 0.16 0.74 FALSE
8 GTEx Esophagus Muscularis RABEP1 0.13 0.09 lasso 10 0.10 2.1e-06 5.8 -5.5 3.7e-08 -0.94 0.02 0.98 FALSE
9 GTEx Lung CAMTA2 0.10 0.02 lasso 3 0.02 1.2e-02 4.1 5.2 2.2e-07 0.36 0.28 0.23 FALSE
10 GTEx Whole Blood RP5-1050D4.2 0.05 0.02 enet 11 0.04 3.1e-04 4.9 5.2 1.7e-07 0.37 0.35 0.54 FALSE
11 NTR Blood MINK1 0.11 0.15 lasso 3 0.15 2.1e-46 5.7 5.4 6.4e-08 0.24 0.01 0.99 FALSE
12 ROSMAP Brain Pre-frontal Cortex RABEP1 0.20 0.22 bslmm 546 0.20 7.4e-25 4.6 -5.5 3.6e-08 -0.75 0.75 0.25 FALSE
13 ROSMAP Brain Pre-frontal Cortex RPAIN 0.06 0.06 lasso 3 0.06 3.1e-08 5.9 -6.1 1.3e-09 -0.98 0.00 1.00 FALSE
14 ROSMAP Brain Pre-frontal Cortex MINK1 0.08 0.06 lasso 3 0.05 4.0e-07 5.3 5.3 1.3e-07 0.31 0.10 0.89 FALSE
15 The Cancer Genome Atlas Glioblastoma Multiforme RABEP1 0.23 0.13 blup 79 0.15 3.4e-05 4.7 -5.7 9.9e-09 -0.77 0.06 0.85 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C17orf107 0.03 0.01 enet 8 0.03 5.1e-04 2.6 5.5 3.8e-08 0.19 0.01 0.68 FALSE
17 The Cancer Genome Atlas Pancreatic Adenocarcinoma C17orf107 0.10 0.03 blup 40 0.05 3.9e-03 4.0 5.2 2.0e-07 0.31 0.03 0.85 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma GP1BA 0.02 0.02 blup 49 0.02 9.3e-03 4.9 5.8 5.9e-09 0.33 0.01 0.79 FALSE
19 The Cancer Genome Atlas Soft Tissue Sarcoma INCA1 0.06 0.00 enet 11 0.00 1.7e-01 4.5 5.5 3.7e-08 0.30 0.01 0.73 FALSE
20 The Cancer Genome Atlas Stomach Adenocarcinoma C17orf107 0.05 0.01 blup 40 0.03 2.0e-03 5.7 5.5 4.9e-08 0.31 0.00 0.96 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma RABEP1 0.04 0.03 enet 5 0.03 1.5e-03 -4.3 -5.3 8.7e-08 -0.67 0.09 0.82 FALSE