[Hub]/) : Traits : Body mass index (BMI) : ← →

chr17:4,041,725-6,068,117

Best TWAS P=2.54e-10 · Best GWAS P=4.08e-09 conditioned to 0.000667

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Putamen basal ganglia	AC012146.7	0.30	0.03	enet	23	0.03	7.6e-02	4.8	-6.3	2.5e-10	-0.45	0.08	0.28	TRUE
13	ROSMAP	Brain Pre-frontal Cortex	RPAIN	0.06	0.06	lasso	3	0.06	3.1e-08	5.9	-6.1	1.3e-09	-0.98	0.00	1.00	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	GP1BA	0.35	0.16	lasso	11	0.18	5.9e-07	4.5	6.0	2.0e-09	0.56	0.16	0.74	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	GP1BA	0.02	0.02	blup	49	0.02	9.3e-03	4.9	5.8	5.9e-09	0.33	0.01	0.79	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	RABEP1	0.23	0.13	blup	79	0.15	3.4e-05	4.7	-5.7	9.9e-09	-0.77	0.06	0.85	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	DHX33	0.12	0.08	lasso	5	0.07	1.8e-03	5.8	-5.6	1.8e-08	-0.96	0.02	0.96	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RABEP1	0.20	0.22	bslmm	546	0.20	7.4e-25	4.6	-5.5	3.6e-08	-0.75	0.75	0.25	FALSE
8	GTEx	Esophagus Muscularis	RABEP1	0.13	0.09	lasso	10	0.10	2.1e-06	5.8	-5.5	3.7e-08	-0.94	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Soft Tissue Sarcoma	INCA1	0.06	0.00	enet	11	0.00	1.7e-01	4.5	5.5	3.7e-08	0.30	0.01	0.73	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf107	0.03	0.01	enet	8	0.03	5.1e-04	2.6	5.5	3.8e-08	0.19	0.01	0.68	FALSE
20	The Cancer Genome Atlas	Stomach Adenocarcinoma	C17orf107	0.05	0.01	blup	40	0.03	2.0e-03	5.7	5.5	4.9e-08	0.31	0.00	0.96	FALSE
11	NTR	Blood	MINK1	0.11	0.15	lasso	3	0.15	2.1e-46	5.7	5.4	6.4e-08	0.24	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	RABEP1	0.04	0.03	enet	5	0.03	1.5e-03	-4.3	-5.3	8.7e-08	-0.67	0.09	0.82	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	RABEP1	0.19	-0.01	lasso	13	0.00	4.2e-01	4.6	-5.3	9.3e-08	-0.82	0.04	0.79	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	MINK1	0.08	0.06	lasso	3	0.05	4.0e-07	5.3	5.3	1.3e-07	0.31	0.10	0.89	FALSE
1	GTEx	Adrenal Gland	RABEP1	0.13	0.03	lasso	13	0.02	7.2e-02	-4.0	-5.2	1.7e-07	-0.80	0.04	0.83	FALSE
10	GTEx	Whole Blood	RP5-1050D4.2	0.05	0.02	enet	11	0.04	3.1e-04	4.9	5.2	1.7e-07	0.37	0.35	0.54	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C17orf107	0.10	0.03	blup	40	0.05	3.9e-03	4.0	5.2	2.0e-07	0.31	0.03	0.85	FALSE
9	GTEx	Lung	CAMTA2	0.10	0.02	lasso	3	0.02	1.2e-02	4.1	5.2	2.2e-07	0.36	0.28	0.23	FALSE
4	GTEx	Colon Sigmoid	GP1BA	0.25	0.17	lasso	4	0.12	3.6e-05	5.0	5.2	2.5e-07	0.28	0.18	0.34	FALSE
3	GTEx	Cells Transformed fibroblasts	GP1BA	0.22	0.10	enet	9	0.18	3.1e-13	5.7	5.1	2.9e-07	0.26	0.03	0.97	FALSE