Best TWAS P=1.71e-12 · Best GWAS P=6.57e-31 conditioned to 5.99e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SAE1 | 0.21 | 0.09 | lasso | 3 | 0.07 | 2.0e-03 | -4.9 | -7.1 | 1.7e-12 | 0.77 | 0.06 | 0.67 | TRUE |
| 2 | METSIM | Adipose | SAE1 | 0.12 | 0.04 | lasso | 5 | 0.07 | 1.7e-10 | -5.1 | -6.5 | 9.5e-11 | 0.61 | 0.61 | 0.39 | FALSE |
| 3 | YFS | Blood | SAE1 | 0.07 | 0.02 | enet | 18 | 0.05 | 3.6e-16 | -6.6 | -5.7 | 1.2e-08 | 0.56 | 0.99 | 0.01 | FALSE |