Best TWAS P=3.32e-08 · Best GWAS P=5.07e-08 conditioned to 0.288
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | PPFIA3 | 0.25 | 0.23 | lasso | 4 | 0.21 | 3.9e-06 | 5.0 | -5.5 | 3.3e-08 | -0.9 | 0.01 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNRNP70 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-02 | 4.8 | -5.1 | 2.9e-07 | -0.7 | 0.01 | 0.68 | FALSE |