Best TWAS P=1.28e-09 · Best GWAS P=4.98e-27 conditioned to 1.7e-16
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | FOSB | 0.28 | 0.00 | lasso | 4 | 0.00 | 0.41300 | -4.9 | -6.1 | 1.3e-09 | 0.44 | 0.88 | 0.12 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SNRPD2 | 0.03 | 0.02 | blup | 36 | 0.02 | 0.00015 | 3.3 | -5.3 | 1.4e-07 | 0.39 | 0.79 | 0.04 | TRUE |