TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Body mass index (BMI)
:
←
→
chr19:45,286,263-46,672,822
Best TWAS P=1.28e-09 · Best GWAS P=4.98e-27 conditioned to 1.7e-16
45.4M
45.6M
45.8M
46M
46.2M
46.4M
46.6M
0
5
10
15
20
25
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Nerve Tibial
FOSB
0.28
0.00
lasso
4
0.00
0.41300
-4.9
-6.1
1.3e-09
0.44
0.88
0.12
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
SNRPD2
0.03
0.02
blup
36
0.02
0.00015
3.3
-5.3
1.4e-07
0.39
0.79
0.04
TRUE