[Hub]/) : Traits : Body mass index (BMI) : ← →

chr21:39,849,553-41,390,857

Best TWAS P=5.51e-08 · Best GWAS P=1.07e-09 conditioned to 0.00199

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Vagina	PSMG1	0.40	0.16	lasso	8	0.20	2.1e-05	4.4	5.4	5.5e-08	0.74	0.13	0.73	TRUE
3	GTEx	Esophagus Mucosa	BRWD1-IT2	0.08	0.06	lasso	5	0.06	3.9e-05	-4.2	-5.4	5.6e-08	-0.88	0.03	0.96	FALSE
7	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMG1	0.04	0.04	blup	61	0.04	2.1e-05	4.5	5.4	8.0e-08	0.82	0.03	0.95	FALSE
8	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PSMG1	0.07	0.04	blup	61	0.06	1.7e-03	-2.9	5.2	1.8e-07	0.71	0.02	0.84	FALSE
4	GTEx	Skin Sun Exposed Lower leg	BRWD1	0.09	0.05	lasso	8	0.04	4.9e-04	-4.7	5.2	2.1e-07	0.58	0.07	0.82	FALSE
1	GTEx	Adipose Subcutaneous	PSMG1	0.19	0.12	enet	26	0.13	4.1e-11	-4.9	5.2	2.2e-07	0.72	0.54	0.46	FALSE
2	GTEx	Breast Mammary Tissue (Female)	PSMG1	0.14	0.09	lasso	11	0.07	3.3e-03	-4.8	5.2	2.3e-07	0.64	0.13	0.59	FALSE
6	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSMG1	0.07	0.07	blup	61	0.04	6.3e-03	-4.9	5.1	2.8e-07	0.76	0.01	0.85	FALSE