[Hub]/) : Traits : Body mass index (BMI) : ← →

chr2:99,468,341-101,731,705

Best TWAS P=4.63e-14 · Best GWAS P=1.06e-13 conditioned to 0.00189

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	AFF3	0.14	0.06	lasso	5	0.07	1.2e-04	-7.2	-7.5	4.6e-14	0.69	0.02	0.98	TRUE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LONRF2	0.06	0.04	blup	69	0.04	3.4e-05	4.8	-6.1	1.1e-09	0.53	0.45	0.53	FALSE
5	GTEx	Thyroid	CHST10	0.05	0.05	lasso	5	0.03	2.6e-03	-4.8	-5.9	4.1e-09	0.39	0.48	0.26	FALSE
4	GTEx	Skin Sun Exposed Lower leg	LONRF2	0.05	0.03	lasso	2	0.02	9.3e-03	5.1	-5.8	5.6e-09	0.42	0.31	0.13	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AFF3	0.31	0.24	enet	32	0.25	9.2e-31	-5.3	-5.5	3.5e-08	0.68	1.00	0.00	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	AFF3	0.31	0.24	enet	38	0.25	3.5e-32	-5.3	-5.5	4.5e-08	0.68	1.00	0.00	FALSE
3	GTEx	Artery Tibial	AFF3	0.06	0.04	enet	6	0.04	4.3e-04	3.6	-5.2	1.6e-07	0.74	0.16	0.78	FALSE
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LONRF2	0.05	0.08	lasso	2	0.08	2.9e-05	5.3	-5.2	2.3e-07	0.48	0.21	0.16	FALSE