[Hub]/) : Traits : Body mass index (BMI) : ← →

chr2:197,660,966-200,117,777

Best TWAS P=2.12e-12 · Best GWAS P=1.71e-11 conditioned to 0.00415

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HSPD1 0.08 0.09 lasso 7 0.09 2.2e-11 -6.1 -6.0 1.6e-09 0.45 0.06 0.94 FALSE
2 GTEx Adipose Subcutaneous RFTN2 0.14 0.10 enet 11 0.13 5.3e-11 -5.5 -6.4 1.3e-10 0.86 0.42 0.57 FALSE
3 GTEx Brain Frontal Cortex BA9 MARS2 0.18 0.12 lasso 2 0.07 5.1e-03 -6.0 6.0 2.1e-09 -0.47 0.09 0.41 FALSE
4 GTEx Cells EBV-transformed lymphocytes HSPD1 0.15 0.04 lasso 7 0.04 2.0e-02 -6.3 6.8 1.4e-11 -0.64 0.05 0.81 FALSE
5 GTEx Lung RFTN2 0.06 0.08 lasso 8 0.06 2.7e-05 -5.9 -5.7 1.5e-08 0.86 0.20 0.80 FALSE
6 GTEx Skin Sun Exposed Lower leg MARS2 0.04 0.05 enet 8 0.03 1.2e-03 -6.2 6.1 8.2e-10 -0.86 0.13 0.86 FALSE
7 GTEx Spleen MARS2 0.12 0.04 lasso 5 0.00 3.4e-01 -6.3 5.6 2.5e-08 -0.82 0.08 0.28 FALSE
8 GTEx Thyroid RFTN2 0.04 0.01 enet 11 0.01 9.5e-02 -6.2 -6.4 1.2e-10 0.80 0.07 0.78 FALSE
9 GTEx Whole Blood PLCL1 0.08 0.08 enet 15 0.05 4.1e-05 -5.8 -6.3 3.9e-10 0.92 0.19 0.81 FALSE
10 METSIM Adipose PLCL1 0.06 0.01 blup 517 0.05 3.6e-08 1.5 -5.6 2.4e-08 0.73 0.18 0.81 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma RFTN2 0.02 0.02 lasso 2 0.01 1.1e-03 -6.1 -6.0 2.2e-09 0.45 0.03 0.90 FALSE
12 The Cancer Genome Atlas Glioblastoma Multiforme RFTN2 0.15 0.10 lasso 1 0.08 2.3e-03 -5.5 -5.5 3.7e-08 0.44 0.02 0.68 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLCL1 0.04 0.00 blup 130 0.02 4.0e-03 2.2 -7.0 2.1e-12 0.65 0.04 0.42 TRUE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MOBKL3 0.03 0.01 blup 32 0.02 6.3e-03 -4.3 -5.3 9.3e-08 0.63 0.01 0.49 FALSE