[Hub]/) : Traits : Body mass index (BMI) : ← →

chr2:197,660,966-200,117,777

Best TWAS P=2.12e-12 · Best GWAS P=1.71e-11 conditioned to 0.00415

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	2.2	-7.0	2.1e-12	0.65	0.04	0.42	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	HSPD1	0.15	0.04	lasso	7	0.04	2.0e-02	-6.3	6.8	1.4e-11	-0.64	0.05	0.81	FALSE
8	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	-6.2	-6.4	1.2e-10	0.80	0.07	0.78	FALSE
2	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	-5.5	-6.4	1.3e-10	0.86	0.42	0.57	FALSE
9	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	-5.8	-6.3	3.9e-10	0.92	0.19	0.81	FALSE
6	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	-6.2	6.1	8.2e-10	-0.86	0.13	0.86	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HSPD1	0.08	0.09	lasso	7	0.09	2.2e-11	-6.1	-6.0	1.6e-09	0.45	0.06	0.94	FALSE
3	GTEx	Brain Frontal Cortex BA9	MARS2	0.18	0.12	lasso	2	0.07	5.1e-03	-6.0	6.0	2.1e-09	-0.47	0.09	0.41	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	RFTN2	0.02	0.02	lasso	2	0.01	1.1e-03	-6.1	-6.0	2.2e-09	0.45	0.03	0.90	FALSE
5	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	-5.9	-5.7	1.5e-08	0.86	0.20	0.80	FALSE
10	METSIM	Adipose	PLCL1	0.06	0.01	blup	517	0.05	3.6e-08	1.5	-5.6	2.4e-08	0.73	0.18	0.81	FALSE
7	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	-6.3	5.6	2.5e-08	-0.82	0.08	0.28	FALSE
12	The Cancer Genome Atlas	Glioblastoma Multiforme	RFTN2	0.15	0.10	lasso	1	0.08	2.3e-03	-5.5	-5.5	3.7e-08	0.44	0.02	0.68	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MOBKL3	0.03	0.01	blup	32	0.02	6.3e-03	-4.3	-5.3	9.3e-08	0.63	0.01	0.49	FALSE