[Hub]/) : Traits : Body mass index (BMI) :

chr1:39,258,674-40,737,589

Best TWAS P=7.21e-11 · Best GWAS P=8.41e-11 conditioned to 0.0216

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BMP8A 0.05 0.03 lasso 3 0.02 8.8e-04 5.1 5.3 1.0e-07 0.71 0.06 0.89 FALSE
2 GTEx Adrenal Gland PABPC4 0.20 0.09 lasso 8 0.06 3.0e-03 5.1 -6.5 7.2e-11 -0.77 0.04 0.85 TRUE
3 GTEx Adrenal Gland RP11-69E11.4 0.11 0.05 lasso 3 0.00 2.4e-01 4.6 5.4 7.0e-08 0.52 0.06 0.48 FALSE
4 GTEx Breast Mammary Tissue (Female) PABPC4 0.10 0.00 enet 9 0.01 1.5e-01 6.0 -6.3 2.4e-10 -0.83 0.04 0.43 FALSE
5 GTEx Cells Transformed fibroblasts PABPC4 0.07 0.09 lasso 1 0.06 2.7e-05 5.1 -5.1 3.1e-07 -0.68 0.12 0.85 FALSE
6 GTEx Nerve Tibial RP11-69E11.8 0.05 0.00 lasso 3 0.01 6.9e-02 5.1 -5.3 8.9e-08 -0.75 0.04 0.85 FALSE
7 NTR Blood PABPC4 0.01 0.00 blup 383 0.00 2.8e-02 5.1 -5.7 1.2e-08 -0.68 0.03 0.66 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BMP8A 0.04 0.03 blup 48 0.04 3.5e-05 4.0 5.7 9.9e-09 0.68 0.02 0.97 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma BMP8A 0.05 0.01 blup 48 0.04 6.8e-05 5.7 6.4 1.6e-10 0.68 0.00 0.98 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma PABPC4 0.09 0.07 enet 5 0.08 4.1e-08 5.1 -6.5 1.1e-10 -0.62 0.00 0.99 FALSE