Best TWAS P=2.96e-08 · Best GWAS P=4.26e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | AP1S1 | 0.39 | 0.22 | enet | 16 | 0.24 | 1.4e-07 | 5.1 | 5.3 | 1.4e-07 | 0.91 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | AP1S1 | 0.18 | 0.14 | lasso | 4 | 0.12 | 1.5e-06 | 5.1 | 5.5 | 3.0e-08 | 0.96 | 0.00 | 0.99 | TRUE |
| 3 | GTEx | Esophagus Mucosa | AP1S1 | 0.16 | 0.08 | lasso | 3 | 0.08 | 2.6e-06 | 5.1 | 5.2 | 1.8e-07 | 0.92 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Pituitary | AP1S1 | 0.41 | 0.27 | lasso | 5 | 0.27 | 2.2e-07 | 4.5 | 5.3 | 1.2e-07 | 0.91 | 0.00 | 0.99 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | AP1S1 | 0.45 | 0.36 | lasso | 6 | 0.39 | 8.6e-34 | 5.1 | 5.3 | 1.2e-07 | 0.96 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Testis | AP1S1 | 0.30 | 0.20 | lasso | 2 | 0.25 | 1.3e-11 | 5.1 | 5.2 | 1.9e-07 | 0.94 | 0.00 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AP1S1 | 0.07 | 0.05 | lasso | 6 | 0.06 | 3.6e-07 | 5.0 | 5.3 | 1.0e-07 | 0.92 | 0.00 | 0.99 | FALSE |