[Hub]/) : Traits : Body mass index (BMI) : ← →

chr7:98,244,565-99,827,148

Best TWAS P=1.54e-12 · Best GWAS P=6.67e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CPSF4 0.06 0.06 blup 313 0.07 6.6e-09 -7.2 -6.6 4.8e-11 0.90 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100289187 0.08 0.02 enet 14 0.03 4.5e-05 -6.1 5.3 9.2e-08 -0.84 0.22 0.78 FALSE
3 GTEx Adipose Visceral Omentum GS1-259H13.2 0.23 0.12 lasso 1 0.09 1.8e-05 -5.9 5.9 2.9e-09 -0.75 0.83 0.07 FALSE
4 GTEx Cells Transformed fibroblasts CPSF4 0.08 0.03 lasso 4 0.03 1.8e-03 -6.1 -6.2 5.6e-10 0.77 0.22 0.46 FALSE
5 GTEx Esophagus Mucosa GS1-259H13.2 0.07 0.07 lasso 3 0.05 1.7e-04 -6.0 6.2 7.3e-10 -0.78 0.28 0.59 FALSE
6 GTEx Lung ZKSCAN5 0.09 0.05 lasso 2 0.03 2.7e-03 -6.1 6.0 1.7e-09 -0.75 0.34 0.25 FALSE
7 GTEx Lung GS1-259H13.2 0.09 0.07 lasso 4 0.05 8.4e-05 -6.0 6.0 2.7e-09 -0.74 0.71 0.16 FALSE
8 GTEx Nerve Tibial GS1-259H13.2 0.15 0.10 lasso 4 0.09 3.4e-07 -6.0 5.9 3.4e-09 -0.73 0.95 0.04 FALSE
9 GTEx Thyroid GS1-259H13.2 0.26 0.05 enet 30 0.08 7.6e-07 -6.0 5.5 3.3e-08 -0.59 0.83 0.12 FALSE
10 METSIM Adipose ARPC1A 0.02 0.02 blup 308 0.02 1.6e-03 -4.7 -6.0 2.0e-09 0.85 0.06 0.89 FALSE
11 METSIM Adipose GS1-259H13.2 0.04 0.03 lasso 3 0.02 1.4e-03 -6.0 6.1 1.4e-09 -0.74 0.21 0.75 FALSE
12 ROSMAP Brain Pre-frontal Cortex GS1-259H13.2 0.07 0.05 bslmm 305 0.06 6.9e-08 -6.4 6.3 2.1e-10 -0.81 0.29 0.71 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma ZKSCAN5 0.03 0.04 lasso 2 0.03 1.0e-04 -7.1 -7.1 1.5e-12 0.98 0.01 0.99 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma ZKSCAN5 0.03 0.03 enet 8 0.03 5.4e-04 -7.2 -5.4 7.5e-08 0.83 0.01 0.86 FALSE