Hub : Genes

AP1S1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1000	0.0360	1.6e-03	0.098	NA	0.109	NA	0.118	2.0e-08	NA	3.4e-09	NA	6.6e-10
2	GTEx	Adrenal Gland	0.6186	0.0764	1.8e-08	0.403	NA	0.438	NA	0.463	1.1e-15	NA	2.6e-17	NA	1.6e-18
3	GTEx	Artery Aorta	0.2260	0.0750	2.7e-03	0.129	NA	0.054	NA	0.095	1.5e-07	NA	5.9e-04	NA	6.5e-06
4	GTEx	Artery Tibial	0.2233	0.0526	1.3e-06	0.184	NA	0.181	NA	0.183	2.5e-14	NA	4.1e-14	NA	2.6e-14
5	GTEx	Brain Cerebellar Hemisphere	0.3030	0.1040	3.4e-03	0.321	NA	0.290	NA	0.302	5.4e-09	NA	3.8e-08	NA	1.7e-08
6	GTEx	Brain Cerebellum	0.3930	0.1150	3.8e-04	0.224	NA	0.235	NA	0.226	3.1e-07	NA	1.4e-07	NA	2.7e-07
7	GTEx	Brain Nucleus accumbens basal ganglia	0.3970	0.1340	2.5e-03	0.065	NA	0.041	NA	0.031	8.2e-03	NA	3.0e-02	NA	5.2e-02
8	GTEx	Breast Mammary Tissue	0.1760	0.0550	6.3e-04	0.138	NA	0.084	NA	0.116	1.4e-07	NA	4.4e-05	NA	1.5e-06
9	GTEx	Colon Transverse	0.4380	0.0810	5.8e-06	0.265	NA	0.257	NA	0.249	6.0e-13	NA	1.4e-12	NA	3.4e-12
10	GTEx	Esophagus Mucosa	0.1560	0.0510	1.3e-03	0.075	NA	0.067	NA	0.085	9.7e-06	NA	3.1e-05	NA	2.6e-06
11	GTEx	Nerve Tibial	0.3387	0.0615	1.5e-10	0.246	NA	0.237	NA	0.235	1.9e-17	NA	8.9e-17	NA	1.2e-16
12	GTEx	Pituitary	0.4120	0.0970	5.0e-05	0.268	NA	0.233	NA	0.266	2.0e-07	NA	1.5e-06	NA	2.2e-07
13	GTEx	Skin Not Sun Exposed Suprapubic	0.3360	0.0630	2.6e-09	0.313	NA	0.242	NA	0.287	1.1e-17	NA	1.8e-13	NA	4.2e-16
14	GTEx	Skin Sun Exposed Lower leg	0.4480	0.0490	0.0e+00	0.355	NA	0.362	NA	0.386	1.6e-30	NA	2.8e-31	NA	8.6e-34
15	GTEx	Testis	0.2980	0.0650	6.2e-06	0.196	NA	0.210	NA	0.253	4.2e-09	NA	1.1e-09	NA	1.3e-11
16	GTEx	Thyroid	0.2110	0.0490	1.6e-06	0.199	NA	0.157	NA	0.198	3.4e-15	NA	4.5e-12	NA	4.5e-15
17	ROSMAP	Brain Pre-frontal Cortex	0.2832	0.0436	0.0e+00	0.269	0.230	0.253	0.27	0.268	1.3e-34	4.5e-29	2.6e-32	1.2e-34	2.0e-34
18	YFS	Blood	0.1477	0.0260	0.0e+00	0.046	0.076	0.089	0.08	0.072	8.5e-15	1.1e-23	1.3e-27	7.1e-25	2.3e-22
19	TCGA	Breast Invasive Carcinoma	0.0385	0.0169	8.3e-06	0.041	0.026	0.037	NA	0.037	6.6e-09	3.4e-06	3.8e-08	NA	3.3e-08
20	TCGA	Colon Adenocarcinoma	0.1020	0.0440	1.1e-03	0.052	0.046	0.028	NA	0.037	6.0e-04	1.2e-03	9.0e-03	NA	3.1e-03
21	TCGA	Kidney Renal Clear Cell Carcinoma	0.1618	0.0477	9.5e-09	0.047	0.066	0.076	NA	0.085	4.6e-06	6.2e-08	6.1e-09	NA	7.6e-10
22	TCGA	Brain Lower Grade Glioma	0.0700	0.0291	2.6e-07	0.023	0.056	0.063	NA	0.055	9.8e-04	5.6e-07	1.0e-07	NA	6.6e-07
23	TCGA	Lung Adenocarcinoma	0.0300	0.0154	1.6e-03	0.009	0.014	-0.001	NA	0.003	2.8e-02	7.5e-03	5.0e-01	NA	1.4e-01
24	TCGA	Prostate Adenocarcinoma	0.0729	0.0302	1.1e-05	0.049	0.051	0.062	NA	0.063	6.4e-06	4.3e-06	4.3e-07	NA	3.6e-07
25	TCGA	Stomach Adenocarcinoma	0.0510	0.0300	3.7e-03	0.039	0.022	0.021	NA	0.032	7.4e-04	8.9e-03	1.1e-02	NA	2.2e-03
26	TCGA	Thyroid Carcinoma	0.1060	0.0410	8.2e-06	0.046	0.048	0.056	NA	0.044	2.6e-05	1.9e-05	3.4e-06	NA	3.9e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Average weekly spirits intake	7.1	8.8	11.9	3.2	3.3	3.3	3.1	2.8	3.0	2.4	2.9	2.9	3.2	2.8	3.1	2.9	3.1	3.1	3.0	2.8	2.2	3.0	3.2	3.5	3.0	2.6	3.3	3.2	1.7
Relative age voice broke	7.0	10.7	14.9	-3.7	-3.1	-3.5	-3.3	-3.5	-3.9	-3.1	-3.3	-2.1	-3.7	-3.5	-3.8	-3.6	-3.8	-3.7	-3.4	-3.5	-1.7	-2.4	-2.0	-3.0	-3.6	-3.4	-3.4	-3.2	-2.3
Smoking status: Previous	5.6	8.4	15.8	3.0	2.2	2.3	2.0	3.7	3.1	3.6	3.8	1.4	3.1	3.1	2.9	3.6	3.3	3.2	3.6	4.0	-0.3	2.7	1.7	2.2	3.2	3.4	2.9	2.8	0.1
Body mass index (BMI)	5.3	22.5	30.7	5.1	5.1	4.8	4.6	5.0	5.3	4.3	5.5	4.8	5.2	4.8	5.3	5.0	5.3	5.2	5.1	5.1	2.1	4.2	4.6	5.1	4.9	3.3	5.3	4.2	1.9
BMI	5.0	29.1	38.2	5.7	5.6	5.2	4.9	5.8	5.9	5.1	6.2	5.0	5.9	5.4	5.8	5.9	6.1	5.9	6.0	6.0	2.5	5.5	5.7	5.8	5.1	3.8	6.0	5.0	2.2
Past tobacco smoking	4.7	8.7	16.5	-2.8	-2.2	-2.1	-1.7	-3.7	-3.1	-3.9	-3.9	-1.4	-3.0	-3.2	-2.9	-3.6	-3.2	-3.1	-3.7	-4.1	0.0	-3.3	-1.9	-2.4	-3.3	-3.0	-2.9	-3.1	0.1
Waist circumference	4.3	15.7	20.1	4.2	4.3	4.0	3.9	4.1	4.1	3.4	4.5	3.8	4.3	4.1	4.4	4.2	4.4	4.3	4.2	4.1	2.7	3.8	4.0	4.4	3.8	2.7	4.5	3.6	1.7
Worry too long after embarrassment	4.2	7.1	14.0	-2.5	-1.7	-1.8	-1.4	-3.4	-2.6	-3.5	-3.3	-1.2	-2.6	-3.2	-2.6	-3.3	-2.9	-2.7	-3.3	-3.2	-0.4	-3.0	-1.0	-2.2	-3.0	-3.2	-2.6	-3.7	-0.5
Number of children fathered	4.1	4.6	8.0	2.4	1.9	2.0	1.9	2.7	2.5	2.2	2.7	1.5	2.5	2.1	2.6	2.7	2.5	2.5	2.5	2.8	-0.3	1.7	1.5	1.9	2.0	1.6	2.3	1.6	0.8
Wears glasses or contact lenses	4.0	4.6	8.7	2.4	2.1	2.1	1.9	2.5	2.2	2.4	2.5	1.7	2.4	2.4	2.5	2.5	2.5	2.5	2.3	2.5	0.2	1.2	2.0	1.5	3.0	1.5	2.1	1.6	0.7
Leg fat percentage (left)	4.0	14.6	27.1	4.0	3.7	3.4	3.3	4.4	3.7	4.1	5.2	3.3	4.1	4.1	4.1	4.4	4.2	4.2	4.4	4.2	1.1	3.6	3.6	3.9	4.4	2.4	4.3	3.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted	3.8	7.9	15.2	-3.1	-2.0	-2.3	-2.3	-3.5	-3.6	-3.6	-3.9	-1.8	-3.1	-2.8	-3.0	-3.5	-3.4	-3.2	-3.2	-3.6	1.0	-1.5	-1.7	-1.7	-3.8	-2.3	-2.7	-2.2	0.2
Leg fat mass (left)	3.8	14.9	22.1	4.1	4.0	3.7	3.6	4.2	3.7	3.7	4.7	3.6	4.2	4.1	4.2	4.2	4.2	4.2	4.3	4.0	1.9	3.8	3.7	4.3	4.1	2.5	4.4	3.7	1.3
Worrier / anxious feelings	3.7	7.0	10.4	-2.9	-3.1	-3.1	-3.2	-2.1	-3.2	-1.2	-1.9	-3.0	-2.9	-2.3	-3.0	-2.3	-2.8	-2.8	-2.2	-2.3	-2.4	-1.6	-3.0	-2.9	-2.7	-2.4	-2.9	-2.1	-3.0
Leg fat mass (right)	3.6	14.0	21.2	4.0	3.9	3.6	3.5	4.0	3.5	3.6	4.6	3.4	4.1	3.9	4.1	4.1	4.1	4.1	4.1	3.8	1.8	3.6	3.6	4.1	4.1	2.4	4.3	3.5	1.2
Prospective memory result	3.5	4.3	5.8	2.1	2.0	1.8	1.7	2.3	2.1	2.0	2.2	1.9	2.2	2.2	2.2	2.3	2.2	2.2	2.4	2.0	1.3	2.3	1.2	2.3	2.0	2.1	2.3	2.3	1.4
Leg fat percentage (right)	3.5	12.8	24.1	3.8	3.5	3.3	3.2	4.1	3.5	3.8	4.9	3.0	3.9	3.7	3.9	4.1	4.0	3.9	4.1	4.0	0.9	3.1	3.4	3.5	4.3	2.2	4.0	2.9	0.3
Arm fat percentage (right)	3.3	13.1	22.2	4.1	3.4	3.5	3.5	4.2	4.1	3.8	4.7	3.2	4.2	3.6	4.3	4.2	4.2	4.2	4.0	4.1	-0.0	2.3	2.7	3.0	4.5	2.8	3.9	2.4	1.0
Impedance of arm (left)	3.2	14.8	28.3	-3.8	-4.7	-4.2	-4.0	-3.0	-4.0	-1.9	-3.0	-5.1	-3.8	-3.6	-3.8	-3.0	-3.7	-3.7	-3.5	-3.3	-4.8	-4.6	-5.2	-5.3	-1.9	-1.8	-4.3	-4.3	-2.6
Arm fat mass (right)	3.2	13.3	17.5	4.0	3.9	3.7	3.7	3.8	3.9	3.1	4.2	3.8	4.0	3.6	4.2	3.9	4.1	4.0	3.9	3.7	1.7	3.2	3.4	3.9	3.8	2.5	4.1	3.2	1.8
Impedance of leg (right)	3.1	14.8	25.0	-4.1	-4.6	-4.3	-4.1	-3.4	-5.0	-2.4	-3.1	-4.6	-4.1	-3.8	-4.2	-3.4	-4.0	-4.0	-3.6	-3.7	-3.1	-3.7	-4.1	-4.6	-2.6	-2.9	-4.2	-4.0	-3.1
Forced vital capacity (FVC), Best measure	3.1	11.3	23.8	-3.7	-2.2	-2.7	-2.6	-4.3	-4.1	-4.3	-4.6	-1.9	-3.8	-3.9	-3.6	-4.2	-4.1	-3.9	-3.9	-4.9	1.4	-1.6	-1.7	-1.7	-4.3	-3.1	-3.1	-2.1	0.1
Arm fat percentage (left)	3.1	12.6	22.8	3.9	3.3	3.2	3.3	4.2	4.0	3.8	4.8	3.0	4.0	3.5	4.1	4.2	4.1	4.0	4.0	4.1	-0.2	2.5	2.7	3.0	4.4	2.7	3.8	2.5	0.7
Arm fat mass (left)	3.1	12.7	17.2	3.9	3.8	3.6	3.6	3.8	3.8	3.2	4.2	3.6	4.0	3.5	4.1	3.8	4.0	4.0	3.8	3.6	1.4	3.1	3.3	3.8	3.9	2.5	4.0	3.0	1.7
Impedance of whole body	3.1	16.0	27.1	-4.1	-4.9	-4.5	-4.3	-3.2	-4.8	-2.1	-3.0	-5.1	-4.1	-3.7	-4.2	-3.3	-4.0	-4.1	-3.6	-3.6	-4.3	-4.1	-4.9	-5.2	-2.3	-2.5	-4.4	-4.2	-3.3
Impedance of arm (right)	3.0	13.9	26.9	-3.6	-4.6	-3.8	-3.5	-3.1	-4.0	-2.3	-3.3	-4.5	-3.6	-3.6	-3.6	-3.1	-3.6	-3.6	-3.6	-3.4	-4.1	-4.9	-4.9	-5.2	-1.9	-1.8	-4.2	-4.5	-1.9
Birth weight	3.0	6.5	12.9	-3.0	-2.5	-2.7	-2.9	-2.7	-3.0	-2.1	-2.5	-1.7	-3.0	-2.8	-3.0	-2.8	-3.0	-3.0	-2.5	-2.9	-0.0	-1.0	-2.3	-2.1	-2.6	-3.6	-2.8	-1.3	-1.6
Ever taken oral contraceptive pill	3.0	3.3	9.4	-2.2	-2.0	-2.4	-2.8	-1.1	-1.8	-0.4	-0.8	-3.1	-2.1	-1.4	-2.1	-1.3	-1.9	-2.0	-1.0	-1.0	-0.7	0.4	-1.7	-1.5	-2.2	-1.9	-1.8	-0.4	-3.0
Whole body fat mass	2.9	12.1	17.7	3.8	3.6	3.4	3.3	3.8	3.4	3.4	4.2	3.4	3.9	3.6	3.9	3.9	3.9	3.9	3.9	3.5	1.3	3.1	3.1	3.6	4.0	2.5	3.9	3.2	1.4
Neuroticism (2016)	2.8	4.0	7.6	-2.5	-2.2	-2.4	-2.8	-1.8	-1.8	-0.9	-1.5	-2.0	-2.4	-2.1	-2.4	-2.0	-2.3	-2.3	-1.6	-1.9	-1.0	-0.3	-2.1	-2.0	-2.0	-2.1	-2.3	-0.7	-2.3
Serious illness, injury or assault of a close relative in last 2 years	2.8	3.2	4.7	-2.0	-2.1	-1.8	-1.7	-1.9	-1.4	-1.5	-1.8	-2.1	-2.0	-1.9	-2.2	-1.9	-2.0	-2.0	-2.0	-1.8	-0.5	-1.9	-2.2	-2.0	-1.3	-0.5	-2.0	-1.3	-1.4
Tense / ‘highly strung’	2.8	4.6	12.3	-1.8	-1.9	-1.3	-1.0	-2.6	-2.4	-2.2	-2.7	-1.3	-1.9	-2.2	-1.9	-2.5	-2.1	-2.0	-2.8	-2.7	-0.8	-3.5	-2.2	-2.4	-1.6	-1.2	-2.3	-2.7	-0.3
Body fat percentage	2.8	11.0	21.4	3.6	3.0	2.9	2.8	4.0	3.3	3.8	4.6	2.7	3.7	3.5	3.7	4.0	3.8	3.7	3.9	3.7	-0.0	2.6	2.3	2.9	4.3	2.5	3.6	2.7	0.4
Basal cell carcinoma (self-reported)	2.8	3.4	5.1	-2.1	-2.2	-2.1	-2.2	-1.8	-2.2	-1.3	-1.6	-1.8	-2.1	-1.4	-2.2	-1.8	-2.0	-2.1	-1.7	-1.8	-0.9	-0.8	-1.8	-1.8	-2.0	-1.9	-2.0	-1.0	-1.8
Hip circumference	2.7	11.6	17.5	3.5	4.0	3.5	3.3	3.2	3.5	2.8	3.6	3.7	3.6	3.2	3.7	3.3	3.6	3.5	3.5	3.3	2.9	3.6	4.2	4.1	3.2	1.6	3.9	3.2	1.7
Medication: Seretide 50 evohaler	2.6	2.9	4.8	1.6	1.8	1.4	1.2	2.0	1.6	2.2	2.1	1.9	1.7	1.7	1.7	2.0	1.7	1.7	2.0	1.8	0.1	2.0	1.8	1.8	1.9	1.3	1.8	1.7	0.2
Lung FEV1/FVC ratio	2.5	12.5	17.0	3.8	3.8	3.7	3.6	3.6	3.7	2.4	3.4	3.8	3.9	4.0	3.6	3.7	3.9	3.9	3.7	4.0	2.5	3.4	3.5	4.1	2.1	3.0	4.0	3.4	2.4
Age when periods started (menarche)	2.5	6.0	9.9	-2.9	-2.8	-3.1	-2.9	-2.1	-2.6	-1.6	-1.9	-2.5	-2.8	-1.9	-2.8	-2.2	-2.7	-2.7	-2.1	-2.1	-3.1	-1.6	-3.1	-2.5	-2.0	-1.8	-2.6	-2.0	-1.9
Impedance of leg (left)	2.5	12.3	22.3	-3.7	-4.3	-4.1	-4.0	-2.8	-4.7	-1.9	-2.5	-4.5	-3.7	-3.1	-3.8	-2.9	-3.7	-3.7	-3.1	-3.3	-2.9	-2.9	-3.9	-4.2	-2.4	-2.6	-3.8	-3.3	-3.5
Forced vital capacity (FVC)	2.5	9.8	20.9	-3.4	-2.1	-2.5	-2.5	-3.9	-4.1	-4.0	-4.4	-1.8	-3.5	-3.6	-3.4	-3.9	-3.8	-3.6	-3.5	-4.6	1.6	-1.2	-1.5	-1.4	-4.0	-2.6	-2.8	-1.7	0.4
Qualifications: nursing, teaching	2.5	3.9	11.2	2.5	2.7	2.9	3.4	1.0	2.1	0.2	1.1	2.7	2.3	1.2	2.4	1.3	2.0	2.2	1.0	1.2	1.5	-0.1	2.8	2.2	1.8	0.8	2.2	0.1	2.4
Worry (Nagel 2018)	2.3	4.8	7.7	-2.1	-2.3	-1.8	-1.6	-2.3	-2.8	-1.4	-2.0	-2.0	-2.1	-2.3	-2.2	-2.3	-2.3	-2.2	-2.5	-2.5	-1.6	-2.7	-2.5	-2.6	-1.4	-1.7	-2.3	-2.6	-1.8
Systolic blood pressure, automated reading	2.3	6.7	9.9	3.1	2.6	3.1	3.1	2.5	3.0	1.6	2.6	3.0	3.1	2.4	3.0	2.6	3.0	3.1	2.4	2.5	1.6	1.0	1.5	2.2	2.9	2.9	2.7	1.9	2.1
Vitamin and mineral supplements	2.3	3.1	5.2	1.6	1.9	1.4	1.3	1.9	1.8	1.7	1.9	1.8	1.7	1.9	1.8	1.9	1.8	1.8	2.1	2.0	0.4	2.3	1.9	2.0	1.3	1.6	1.9	2.0	0.5
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	4.8	-1.4	-2.0	-1.4	-1.3	-1.4	-1.6	-1.3	-1.2	-1.6	-1.4	-1.9	-1.6	-1.4	-1.5	-1.4	-1.6	-1.5	-1.4	-2.2	-1.9	-2.1	-0.8	-1.1	-1.8	-1.7	-0.8
Health satisfaction	2.3	3.0	10.2	1.7	1.5	1.3	1.2	2.1	1.7	2.5	2.3	1.1	1.8	1.7	1.8	2.0	1.9	1.8	1.9	2.2	-0.1	1.0	1.3	1.1	3.2	1.3	1.6	1.3	0.2
Mouth/teeth dental problems: Bleeding gums	2.2	2.8	12.7	1.8	0.6	1.2	1.1	2.1	1.6	1.9	1.7	0.3	1.8	1.9	1.7	2.1	2.0	1.9	1.8	2.3	-1.0	0.2	-0.5	0.2	2.2	3.6	1.2	1.3	0.6
Trunk fat percentage	2.1	8.3	16.2	3.1	2.5	2.4	2.5	3.5	2.7	3.4	4.0	2.2	3.2	3.1	3.3	3.5	3.3	3.2	3.3	3.1	-0.3	2.0	1.7	2.3	4.0	2.5	3.1	2.3	0.5
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	3.6	-1.6	-1.4	-1.4	-1.3	-1.8	-1.1	-1.6	-1.3	-1.3	-1.6	-1.8	-1.6	-1.7	-1.7	-1.6	-1.8	-1.5	-0.8	-1.7	-1.1	-1.7	-1.0	-1.9	-1.8	-1.8	-1.5
Age at First Birth	2.0	2.9	6.2	-1.9	-1.3	-1.6	-1.4	-2.1	-1.9	-2.1	-2.1	-1.4	-1.9	-1.9	-1.9	-2.2	-2.0	-1.9	-1.9	-1.9	0.5	-1.0	-1.1	-1.1	-2.5	-1.4	-1.6	-1.3	-0.7
Trunk fat mass	2.0	8.7	13.1	3.2	2.9	2.8	2.7	3.3	2.8	3.0	3.6	2.8	3.2	3.1	3.3	3.3	3.3	3.3	3.3	2.9	1.0	2.6	2.5	3.0	3.5	2.3	3.3	2.8	1.2
Nervous feelings	2.0	3.6	7.1	-1.8	-1.6	-1.4	-1.1	-2.3	-2.5	-2.0	-2.7	-1.1	-1.9	-2.3	-2.0	-2.3	-2.1	-2.0	-2.4	-2.5	-0.0	-2.3	-1.1	-1.7	-1.7	-1.4	-1.9	-2.4	0.3
Gout (self-reported)	2.0	2.7	6.5	2.0	1.9	2.0	2.2	1.5	2.1	1.2	1.6	1.4	2.0	1.2	2.2	1.6	1.9	2.0	1.3	1.7	-0.1	-0.1	1.3	1.2	2.5	1.3	1.7	0.4	1.1
Suffer from ‘nerves’	2.0	3.1	6.4	-1.7	-2.0	-1.6	-1.4	-1.8	-2.5	-1.0	-1.5	-1.7	-1.8	-1.6	-1.8	-1.8	-1.9	-1.8	-1.9	-2.3	-1.2	-2.2	-2.1	-1.9	-0.8	-1.1	-1.8	-1.9	-1.5
Overall health rating	2.0	4.2	13.2	1.6	0.9	0.7	0.3	2.9	1.9	3.6	3.3	0.2	1.8	2.2	1.7	2.7	2.0	1.9	2.7	2.7	-1.7	2.2	0.7	0.9	2.9	1.8	1.7	2.0	-1.1
Weight	1.9	9.3	16.2	3.1	3.6	3.2	3.1	2.7	2.8	2.0	2.7	3.6	3.1	2.8	3.2	2.8	3.1	3.1	3.0	2.5	3.2	3.4	3.6	4.0	2.6	1.8	3.5	3.3	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.0	13.4	-2.6	-1.2	-1.7	-1.5	-3.2	-3.0	-3.5	-3.6	-0.9	-2.7	-2.7	-2.6	-3.2	-3.0	-2.8	-2.9	-3.7	1.6	-1.0	-0.9	-0.8	-3.5	-2.1	-2.0	-1.4	0.7
Average weekly red wine intake	1.9	2.8	4.6	1.7	1.8	1.9	1.8	1.4	1.6	0.9	1.1	1.8	1.7	1.8	1.6	1.5	1.6	1.7	1.6	1.5	2.1	1.7	1.5	2.1	1.3	1.8	1.9	1.9	1.9
Diabetes diagnosed by doctor	1.9	3.1	5.6	1.8	1.6	1.6	1.4	1.9	2.1	2.1	1.7	1.4	1.8	1.9	1.8	1.9	1.9	1.9	1.9	2.4	0.4	1.6	1.6	1.5	2.0	1.9	1.8	1.5	1.0
Alzheimer’s Disease (in mother)	1.8	2.1	4.2	1.5	1.3	1.5	1.4	1.4	1.5	1.3	0.9	1.1	1.6	1.9	1.5	1.5	1.6	1.6	1.3	1.4	1.1	0.8	0.9	1.1	2.1	1.9	1.4	1.3	1.7
Lupus	1.8	2.7	5.1	1.9	2.0	2.0	2.2	1.3	1.9	1.2	1.9	2.0	1.9	1.7	1.9	1.4	1.8	1.9	1.3	1.3	-0.1	0.3	2.2	1.5	2.2	1.0	1.8	0.4	0.3
Smoking Status	1.8	4.3	11.8	1.6	1.2	1.0	0.4	2.7	1.7	3.0	3.3	0.5	1.7	2.1	1.7	2.6	2.0	1.8	2.8	2.8	0.2	3.4	1.0	1.9	1.9	1.3	2.0	3.0	-1.4
Type 2 Diabetes (T2D) (2018)	1.8	3.3	6.2	1.9	2.0	1.7	1.6	1.9	2.1	1.7	1.8	1.4	1.9	2.0	1.8	1.9	2.0	1.9	2.0	2.5	0.7	2.0	2.4	2.0	1.4	1.5	2.0	1.3	0.8
Medication: Omeprazole	1.8	2.1	5.2	1.8	1.3	1.7	1.8	1.5	2.3	1.1	1.5	1.1	1.8	1.5	1.9	1.5	1.8	1.8	1.3	1.8	0.1	-0.1	0.8	0.9	1.2	1.7	1.4	0.5	0.7
Long-standing illness, disability or infirmity	1.8	2.8	7.0	1.7	0.8	1.1	1.0	2.2	2.1	2.6	2.4	0.7	1.7	1.6	1.6	2.2	2.0	1.8	1.9	2.5	-1.6	0.7	1.0	0.5	2.2	1.7	1.4	0.9	-0.6
Type 2 Diabetes (T2D) (2012)	1.7	1.9	4.9	-1.5	-2.0	-1.6	-1.8	-1.2	-1.5	-0.9	-1.1	-1.6	-1.4	-1.5	-1.5	-1.4	-1.2	-1.3	-1.1	-1.1	-0.9	-0.8	-2.2	-1.7	-1.3	-0.8	-1.8	-0.7	-1.0
Hearing difficulty/problems: Yes	1.7	2.6	4.5	1.6	1.3	1.2	1.1	2.0	2.1	1.9	1.7	1.7	1.7	2.0	1.5	1.9	1.8	1.7	1.9	2.1	0.5	1.5	1.3	1.4	1.4	1.7	1.6	1.7	1.0
Forced expiratory volume in 1-second (FEV1)	1.7	5.7	12.6	-2.5	-1.2	-1.6	-1.5	-3.1	-3.1	-3.5	-3.5	-0.9	-2.6	-2.5	-2.5	-3.0	-2.9	-2.7	-2.7	-3.5	1.7	-0.9	-0.9	-0.6	-3.4	-1.9	-1.9	-1.2	0.9
Length of working week for main job	1.7	1.9	3.6	-1.7	-1.6	-1.9	-1.8	-1.1	-1.9	-0.7	-0.8	-1.7	-1.6	-1.7	-1.8	-1.2	-1.5	-1.6	-1.0	-1.1	-1.2	-0.4	-1.3	-1.1	-1.2	-0.7	-1.4	-0.5	-1.5
Ever had bowel cancer screening	1.7	2.0	3.2	1.6	1.5	1.6	1.6	1.4	1.8	1.2	1.2	1.7	1.6	1.3	1.6	1.4	1.5	1.6	1.3	1.4	0.6	0.5	1.5	1.2	1.5	1.2	1.4	1.1	1.0
Ever smoked	1.7	3.0	8.1	1.4	1.2	1.0	0.5	2.2	1.8	2.5	2.1	0.7	1.5	1.8	1.5	2.1	1.7	1.6	2.3	2.5	0.4	2.9	1.0	1.6	1.5	1.8	1.6	2.3	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	2.8	-1.6	-1.3	-1.4	-1.4	-1.6	-1.7	-1.2	-1.3	-1.1	-1.6	-1.6	-1.5	-1.6	-1.6	-1.6	-1.6	-1.6	-0.7	-1.4	-1.1	-1.5	-1.1	-1.7	-1.6	-1.7	-1.0
Supplements: Glucosamine	1.6	2.0	6.8	1.6	1.6	1.6	1.5	1.4	2.6	1.1	1.6	0.8	1.6	1.1	1.6	1.4	1.6	1.6	1.4	1.7	1.0	1.3	1.8	1.4	0.8	0.4	1.5	1.1	-0.2
Medication: Allopurinol	1.6	2.1	4.2	1.6	1.9	1.8	2.0	1.0	2.0	0.7	1.2	1.7	1.6	0.8	1.7	1.1	1.5	1.5	1.0	1.2	0.9	0.4	1.7	1.5	2.1	1.1	1.6	0.6	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	3.8	-1.1	-1.5	-1.0	-0.9	-1.4	-1.6	-1.4	-1.7	-0.9	-1.2	-1.2	-1.1	-1.4	-1.3	-1.2	-1.5	-1.8	-1.3	-1.9	-1.6	-1.6	-0.8	-0.9	-1.5	-1.8	0.6
Medication: Gliclazide	1.6	1.8	4.0	1.2	1.3	1.0	0.9	1.5	1.9	1.8	1.4	1.1	1.3	1.1	1.4	1.5	1.3	1.3	1.5	1.7	-0.2	1.3	1.1	1.1	2.0	1.6	1.3	1.3	0.5
Average weekly champagne plus white wine intake	1.6	2.2	9.3	1.6	1.8	2.3	2.7	-0.0	1.6	-1.2	-0.3	2.3	1.4	0.9	1.5	0.2	1.1	1.2	-0.1	-0.1	1.9	-0.7	1.9	1.5	0.5	0.3	1.3	-0.6	3.0
Medication: Blood pressure	1.6	3.0	4.6	1.9	2.1	1.9	2.0	1.6	2.1	1.2	1.8	2.1	1.9	1.6	1.8	1.6	1.8	1.8	1.6	1.5	1.4	1.2	1.7	2.0	2.1	1.3	2.0	1.6	1.1
Qualifications: CSEs or equivalent	1.5	2.0	5.0	-1.5	-2.1	-1.9	-2.0	-0.6	-1.8	-0.1	-0.7	-2.2	-1.4	-0.8	-1.6	-0.7	-1.3	-1.3	-0.7	-0.9	-1.8	-0.6	-2.2	-1.6	-1.3	-0.4	-1.4	-0.5	-1.5
Medication: Levothyroxine sodium	1.5	2.6	6.6	1.6	1.9	1.9	1.8	1.1	1.5	0.9	1.0	1.8	1.6	2.0	1.5	1.2	1.5	1.5	1.3	1.6	2.6	1.6	2.5	2.1	1.0	1.3	1.7	1.3	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	4.2	1.4	0.8	1.0	0.9	1.7	1.9	1.7	1.8	0.3	1.5	1.3	1.4	1.7	1.6	1.5	1.6	2.0	-0.7	0.8	-0.1	0.5	1.3	1.6	1.1	1.4	-0.3
Osteoarthritis (self-reported)	1.5	2.0	4.3	1.5	1.6	1.5	1.5	1.4	1.7	1.3	1.8	1.2	1.5	1.0	1.4	1.4	1.6	1.5	1.4	1.5	0.6	1.0	2.1	1.5	1.7	0.5	1.5	0.8	0.1
Medication: Atorvastatin	1.5	1.8	6.6	1.1	1.0	0.7	0.4	1.7	1.1	1.7	1.8	1.1	1.2	1.2	1.1	1.6	1.3	1.3	1.9	1.6	1.0	2.6	1.3	1.5	0.5	0.7	1.3	1.9	-0.4
Ulcerative Colitis (UC)	1.4	2.7	6.3	-1.6	-1.9	-1.9	-1.8	-1.1	-2.3	-0.8	-1.1	-1.5	-1.6	-1.9	-1.6	-1.2	-1.7	-1.6	-1.3	-1.7	-1.9	-1.6	-2.5	-2.1	-1.0	-0.3	-1.7	-1.1	-1.4
Hand grip strength (right)	1.4	3.9	10.2	-2.1	-0.8	-1.3	-1.3	-2.5	-2.2	-2.7	-3.0	-0.2	-2.1	-1.9	-2.0	-2.5	-2.3	-2.2	-2.0	-2.8	2.2	0.1	-0.2	-0.1	-3.2	-2.3	-1.5	-0.4	1.0
Standing height	1.4	13.6	31.9	-4.0	-2.7	-3.0	-3.0	-4.5	-4.8	-4.5	-5.7	-2.1	-4.1	-3.9	-4.1	-4.5	-4.4	-4.2	-4.1	-5.2	2.5	-1.3	-2.0	-1.9	-4.7	-2.7	-3.4	-1.4	1.3
Qualifications: O levels/GCSEs or equivalent	1.4	2.3	7.7	-1.1	-0.8	-0.5	-0.2	-2.0	-1.4	-2.8	-2.3	-0.3	-1.2	-1.7	-1.2	-1.9	-1.4	-1.3	-2.0	-1.9	0.8	-2.1	-0.5	-1.1	-1.8	-1.5	-1.3	-1.9	0.9
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	5.3	1.8	2.0	2.1	2.0	1.2	1.7	1.0	1.1	1.6	1.7	2.0	1.8	1.3	1.7	1.7	1.3	1.7	2.2	1.3	2.3	2.0	1.3	1.4	1.8	1.0	1.1
Leg pain on walking	1.4	1.7	4.3	1.5	1.4	1.4	1.4	1.3	1.2	1.2	1.4	1.4	1.4	1.4	1.4	1.4	1.5	1.4	1.3	1.5	0.1	0.8	0.9	1.1	2.1	1.1	1.4	1.1	0.7
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.9	1.6	1.4	1.7	1.7	1.1	2.0	0.8	1.2	1.2	1.6	1.6	1.7	1.2	1.6	1.5	1.1	1.4	0.9	0.3	0.9	1.2	0.9	1.2	1.4	0.5	0.9
Hypothyroidism (self reported)	1.3	2.9	15.0	1.5	2.2	2.2	2.2	0.5	1.7	-0.0	0.3	2.5	1.4	1.5	1.4	0.6	1.3	1.4	0.7	1.0	3.9	1.1	2.7	2.3	0.6	1.1	1.7	0.8	1.9
Relative age of first facial hair	1.3	2.7	5.3	-1.6	-1.4	-1.2	-1.0	-2.0	-1.8	-2.2	-1.6	-0.6	-1.6	-2.2	-1.7	-1.9	-1.7	-1.7	-2.0	-1.8	-0.3	-2.0	-0.9	-1.5	-1.3	-1.8	-1.6	-2.3	-0.6
Age at last live birth	1.3	1.8	4.4	-0.9	-0.8	-0.6	-0.3	-1.6	-1.5	-2.1	-2.1	-0.9	-1.0	-1.5	-1.0	-1.5	-1.2	-1.1	-1.6	-1.6	-0.5	-1.8	-0.7	-1.1	-1.9	-1.5	-1.2	-1.7	1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	3.4	1.3	0.7	1.0	0.8	1.5	1.7	1.5	1.6	0.4	1.3	1.1	1.4	1.5	1.4	1.3	1.4	1.8	-0.2	1.0	0.7	0.8	0.9	0.8	1.1	1.0	-0.3
Pack years of smoking	1.3	1.9	4.3	1.2	1.1	0.9	0.7	1.6	1.5	1.8	1.5	0.9	1.3	1.4	1.4	1.6	1.5	1.3	1.7	2.1	1.0	2.0	1.1	1.4	1.2	1.0	1.3	1.8	0.4
Multivitamins +/- minerals	1.2	1.5	3.6	-0.9	-1.1	-0.6	-0.5	-1.4	-1.1	-1.7	-1.7	-0.8	-1.0	-1.3	-1.0	-1.3	-1.1	-1.0	-1.5	-1.3	0.1	-1.9	-1.2	-1.4	-1.4	-0.8	-1.3	-1.6	0.4
Mouth/teeth dental problems	1.2	1.8	3.5	-1.5	-1.2	-1.4	-1.2	-1.6	-1.3	-1.0	-1.2	-0.9	-1.6	-1.5	-1.6	-1.6	-1.6	-1.6	-1.6	-1.6	-0.9	-1.1	-1.0	-1.1	-0.4	-1.9	-1.4	-1.6	-1.1
Ever highly irritable/argumentative for 2 days	1.2	1.5	4.0	1.3	1.1	1.1	1.1	1.4	1.4	1.7	1.6	0.7	1.3	1.4	1.3	1.4	1.4	1.3	1.2	1.3	-0.1	0.6	0.7	1.0	2.0	0.9	1.3	1.0	-0.1
Mood swings	1.2	2.1	4.8	-1.8	-1.4	-1.9	-1.9	-1.3	-1.9	-0.9	-1.4	-1.4	-1.8	-1.5	-2.0	-1.4	-1.6	-1.8	-1.2	-0.9	-0.7	-0.1	-1.1	-0.9	-2.2	-1.3	-1.4	-1.0	-1.1
Number of operations (self-reported)	1.2	1.7	6.7	-1.3	-1.8	-1.9	-2.2	-0.1	-0.2	1.1	0.2	-2.2	-1.2	-0.9	-1.2	-0.2	-0.9	-1.1	-0.2	0.2	-2.6	-0.0	-1.3	-1.6	0.0	-0.5	-1.3	-0.4	-2.5
Neuroticism (Nagel 2018)	1.1	2.6	4.7	-1.6	-1.0	-1.2	-1.0	-2.0	-2.2	-1.8	-2.1	-1.0	-1.7	-1.9	-1.8	-2.0	-1.9	-1.7	-1.9	-2.0	-0.2	-1.2	-1.2	-1.1	-2.0	-1.5	-1.5	-1.8	-0.6
Schizophrenia vs Biploar Disorder	1.1	1.4	4.0	0.8	0.6	0.3	-0.0	1.7	1.1	2.0	1.6	-0.1	0.9	1.5	0.9	1.5	1.2	1.0	1.6	1.5	-1.0	1.2	-0.1	0.4	2.0	1.4	0.8	1.6	0.0
Rheumatoid Arthritis	1.1	1.5	4.1	1.0	0.8	0.6	0.3	1.6	1.1	2.0	1.6	0.6	1.1	1.5	1.2	1.5	1.2	1.1	1.6	1.6	0.1	1.6	0.7	0.7	1.5	1.6	1.0	1.7	-0.5
Blood Red Count	1.1	10.7	83.4	2.3	1.4	1.1	2.2	2.5	3.8	4.3	4.3	1.8	2.4	-0.1	2.5	2.8	2.4	2.3	1.6	1.1	-8.3	-3.1	1.2	-0.7	9.1	0.8	1.7	-1.7	-1.0
Severe depression (siblings)	1.1	1.3	3.2	1.2	0.5	0.6	0.7	1.5	1.4	1.3	1.3	0.4	1.3	0.9	1.4	1.5	1.3	1.3	1.3	1.5	-1.8	0.0	-0.6	0.0	0.9	1.6	0.8	0.8	0.4
Townsend deprivation index at recruitment	1.1	1.6	5.1	-1.4	-1.2	-1.8	-2.3	-0.3	-0.8	0.5	-0.1	-2.0	-1.3	-1.2	-1.5	-0.5	-1.0	-1.2	-0.1	-0.5	-0.9	1.5	-1.3	-0.6	-1.2	-1.6	-1.0	1.1	-2.0
Neuroticism score	1.1	2.4	4.0	-1.7	-1.3	-1.5	-1.3	-1.8	-1.9	-1.2	-1.9	-1.4	-1.7	-2.0	-1.8	-1.8	-1.8	-1.7	-1.7	-1.7	-0.7	-1.4	-0.9	-1.3	-1.5	-1.1	-1.5	-1.9	-0.4
Qualifications: College or University degree	1.1	3.5	19.8	1.5	2.5	2.6	3.0	-0.5	1.5	-1.9	-1.4	2.6	1.3	0.7	1.4	-0.2	0.9	1.1	-0.3	-0.3	3.6	-0.4	2.5	2.1	-0.1	0.8	1.4	-0.4	4.4
Mouth/teeth dental problems: Loose teeth	1.1	1.4	3.0	1.2	0.6	0.7	0.7	1.6	0.9	1.7	1.7	0.3	1.2	1.2	1.2	1.6	1.4	1.3	1.4	1.5	-1.1	0.4	0.3	0.3	1.7	1.5	0.9	0.9	-0.5
Angina (self-reported)	1.1	1.4	3.1	1.0	1.0	0.7	0.5	1.5	1.4	1.8	1.4	0.9	1.1	1.1	1.0	1.4	1.2	1.1	1.5	1.5	-0.5	1.7	1.3	1.1	1.2	1.0	1.1	1.3	-0.1
Migraine (self-reported)	1.1	1.4	6.0	1.4	1.2	1.3	1.6	0.9	1.6	1.1	1.0	0.6	1.3	0.9	1.4	1.0	1.2	1.3	0.8	1.0	0.4	-0.1	0.9	0.8	2.4	1.3	1.2	0.1	1.2
Risk taking	1.1	1.6	2.8	1.4	1.2	1.2	1.2	1.5	1.3	1.7	1.6	0.9	1.4	1.2	1.4	1.5	1.4	1.4	1.4	1.4	-0.3	1.0	1.5	1.2	1.1	0.8	1.4	1.1	-0.1
Pain experienced in last month	1.1	1.8	8.5	1.3	1.9	1.9	2.1	0.3	1.4	-0.3	-0.1	1.9	1.3	0.9	1.3	0.5	1.0	1.1	0.4	0.3	1.7	0.1	1.4	1.8	1.0	0.9	1.4	0.5	2.9
Ever had hysterectomy (womb removed)	1.0	1.1	2.7	-1.3	-1.1	-1.5	-1.5	-0.9	-0.5	-0.4	-0.6	-1.1	-1.3	-1.1	-1.3	-1.0	-1.2	-1.2	-0.8	-0.8	-0.7	-0.4	-0.9	-1.2	-1.1	-0.8	-1.2	-0.6	-1.7
Pack years adult smoking proportion	1.0	1.6	3.9	1.1	0.9	0.7	0.4	1.6	1.4	1.8	1.5	0.5	1.1	1.3	1.2	1.6	1.4	1.2	1.6	2.0	0.5	1.8	0.7	1.1	1.2	1.0	1.2	1.7	-0.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	8.5	-0.4	0.6	0.2	0.6	-1.4	-0.3	-2.0	-2.1	1.7	-0.5	-0.6	-0.4	-1.2	-0.8	-0.6	-1.2	-1.2	1.9	-0.7	0.5	0.6	-0.6	-0.2	-0.1	-0.7	2.9
Birth weight of first child	1.0	1.9	3.5	-1.5	-1.5	-1.3	-1.2	-1.7	-1.9	-1.3	-1.7	-0.9	-1.5	-1.7	-1.7	-1.7	-1.6	-1.6	-1.5	-1.8	0.3	-0.7	-0.9	-1.0	-0.8	-1.6	-1.4	-1.0	0.0
Neck or shoulder pain in last month	1.0	1.5	6.5	0.3	-0.1	-0.4	-0.9	1.6	1.2	2.2	2.2	-0.9	0.4	0.6	0.4	1.4	0.7	0.5	1.5	1.6	-0.8	2.0	-0.4	0.2	0.6	-0.3	0.5	1.6	-2.6
Pulse rate, automated reading	1.0	3.4	18.8	-1.5	-0.9	-1.0	-1.3	-1.5	-4.2	-1.3	-0.3	0.3	-1.5	-1.5	-1.6	-1.6	-2.0	-1.5	-1.3	-3.8	1.2	0.3	0.3	-0.4	-0.9	-4.3	-1.2	-0.4	-2.1
Financial situation satisfaction	1.0	1.3	5.1	0.8	1.4	1.0	0.8	0.7	0.7	0.4	0.8	1.4	0.9	0.9	1.0	0.7	0.7	0.8	1.0	0.7	2.2	2.0	0.8	1.8	0.2	0.4	1.2	2.0	0.5
Medication: Lisinopril	1.0	1.3	4.0	-0.9	-0.1	-0.4	-0.1	-1.6	-1.0	-2.0	-1.8	0.0	-1.0	-1.4	-0.9	-1.5	-1.1	-1.1	-1.6	-1.4	0.2	-1.5	-0.0	-0.6	-0.9	-0.8	-0.9	-1.5	1.3
Arm fat-free mass (left)	1.0	5.1	20.6	1.8	2.9	2.4	2.4	0.9	1.4	-0.0	0.6	3.5	1.8	1.5	1.8	1.0	1.6	1.7	1.5	0.8	4.5	3.1	3.4	3.7	0.4	0.7	2.4	2.8	2.9
Myopia	1.0	1.5	2.5	-1.4	-1.5	-1.6	-1.5	-1.1	-0.9	-0.5	-1.4	-1.5	-1.4	-1.3	-1.5	-1.1	-1.3	-1.3	-1.1	-1.1	-1.0	-0.9	-1.5	-1.4	-0.6	0.3	-1.4	-0.7	-0.5
Irritable Bowel Disease (IBD)	0.9	2.3	7.7	-1.4	-1.7	-1.8	-1.8	-0.6	-1.8	-0.2	-0.1	-1.4	-1.3	-1.7	-1.2	-0.7	-1.3	-1.2	-0.8	-1.2	-2.8	-1.2	-2.2	-2.0	-1.0	-1.1	-1.5	-0.9	-2.6
Ovarian Cancer	0.9	1.2	2.7	1.1	1.0	0.9	0.7	1.3	1.1	1.0	1.6	1.3	1.1	0.6	0.9	1.2	1.1	1.1	1.3	1.4	0.6	1.6	1.5	1.2	1.1	-0.3	1.1	1.2	-0.2
HbA1C	0.9	1.0	1.9	1.1	1.3	1.3	1.4	0.7	1.4	0.4	0.8	1.2	1.2	1.2	1.3	0.7	1.0	1.1	0.8	0.5	0.5	0.1	1.1	0.9	0.8	0.9	1.0	0.7	1.1
Sensitivity / hurt feelings	0.9	1.6	4.2	-1.1	-0.6	-0.5	-0.2	-1.9	-1.0	-1.9	-2.0	-0.3	-1.1	-1.5	-1.1	-1.8	-1.3	-1.2	-1.8	-1.5	0.2	-1.9	-0.3	-0.9	-0.7	-0.8	-1.1	-2.0	0.8
Stomach or abdominal pain in last month	0.9	1.1	3.0	0.8	0.3	0.4	0.2	1.4	1.2	1.5	1.5	0.6	0.9	1.1	0.8	1.3	1.1	0.9	1.2	1.6	-1.6	0.6	-0.3	0.2	1.7	1.1	0.7	0.8	0.0
Arm fat-free mass (right)	0.9	4.4	17.6	1.6	2.7	2.1	2.0	0.9	1.4	0.2	0.6	3.0	1.6	1.5	1.6	0.9	1.4	1.5	1.4	0.7	4.2	3.2	3.0	3.5	0.2	0.6	2.2	3.1	2.3
Breast cancer (self-reported)	0.9	1.1	2.5	-1.0	-1.0	-1.1	-0.9	-0.9	-0.8	-0.8	-1.6	-1.1	-1.0	-1.2	-1.0	-1.0	-1.1	-1.0	-1.0	-1.0	-1.3	-1.2	-1.0	-1.2	-1.6	0.3	-1.1	-0.9	0.1
Commuting to job workplace: Public transport	0.9	1.1	3.0	1.0	1.2	1.1	1.0	0.8	0.7	0.6	0.4	1.0	0.9	1.1	1.0	0.8	0.9	0.9	1.0	0.8	1.7	1.5	1.3	1.6	0.4	0.6	1.2	1.4	1.4
Illnesses of father: High blood pressure	0.9	1.1	2.7	-1.2	-1.1	-1.2	-1.0	-1.1	-1.6	-0.6	-1.0	-0.8	-1.2	-1.1	-1.4	-1.1	-1.3	-1.2	-1.2	-1.1	-0.8	-1.0	-0.7	-1.1	0.2	0.2	-1.1	-1.4	-0.7
Arm predicted mass (left)	0.9	4.5	18.1	1.7	2.8	2.4	2.3	0.8	1.3	-0.1	0.5	3.3	1.7	1.3	1.8	0.9	1.5	1.6	1.3	0.7	4.2	2.7	3.1	3.4	0.2	0.6	2.2	2.6	2.7
Angina	0.8	1.1	2.8	0.9	0.9	0.6	0.3	1.3	1.2	1.7	1.3	0.6	0.9	0.9	0.9	1.2	1.0	0.9	1.3	1.3	-0.5	1.6	1.1	0.9	1.1	0.8	1.0	1.1	-0.2
Medication: Co-codamol	0.8	0.9	2.9	0.4	0.2	-0.1	-0.4	1.3	1.1	1.5	1.5	-0.7	0.5	0.7	0.5	1.2	0.7	0.6	1.3	1.2	0.2	1.7	0.6	0.6	0.9	0.1	0.6	1.6	-0.9
Medication: Atenolol	0.8	1.0	3.9	1.1	1.1	1.1	1.3	0.8	1.3	1.0	1.0	1.2	1.1	0.8	1.0	0.8	1.0	1.0	0.7	0.9	-0.5	-0.2	1.4	0.7	2.0	1.1	1.0	-0.1	0.6
Breastfed as a baby	0.8	0.9	2.6	1.2	1.2	1.3	1.6	0.6	1.0	0.1	0.5	1.0	1.2	0.6	1.1	0.7	1.1	1.1	0.5	0.8	0.4	-0.6	1.0	0.7	1.3	1.0	1.0	-0.4	1.6
Age at first live birth	0.8	1.5	6.8	-0.4	0.1	0.3	0.6	-1.6	-0.5	-2.2	-2.5	0.2	-0.5	-1.1	-0.6	-1.4	-0.7	-0.6	-1.5	-1.1	0.7	-1.7	0.3	-0.4	-1.5	-0.8	-0.7	-1.3	2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.5	1.0	0.7	0.7	0.6	1.3	1.0	1.6	1.2	0.5	1.0	1.0	0.9	1.3	1.1	1.0	1.3	1.3	-0.7	1.1	0.9	0.9	0.8	1.2	1.0	0.9	-0.2
Leg fat-free mass (right)	0.8	4.1	10.4	1.8	2.6	2.2	2.2	1.2	1.7	0.4	0.8	2.8	1.8	1.6	1.9	1.2	1.7	1.8	1.6	1.0	3.2	2.5	2.5	3.1	0.9	1.2	2.2	2.7	2.7
Leg predicted mass (right)	0.8	4.2	10.2	1.9	2.6	2.2	2.2	1.2	1.8	0.4	0.8	2.8	1.9	1.6	2.0	1.2	1.7	1.8	1.6	1.0	3.2	2.4	2.5	3.1	0.9	1.3	2.3	2.7	2.8
Number of self-reported non-cancer illnesses	0.8	1.4	2.8	1.3	1.0	1.1	1.2	1.3	1.3	1.2	1.5	1.4	1.3	1.1	1.4	1.3	1.3	1.3	1.1	1.4	-0.0	0.3	1.0	0.7	1.7	1.3	1.1	0.5	0.4
Basal metabolic rate	0.8	4.5	16.0	1.8	2.8	2.4	2.3	1.0	1.5	0.1	0.6	3.0	1.8	1.4	1.9	1.1	1.6	1.7	1.4	0.8	4.0	2.6	3.0	3.4	0.6	0.9	2.3	2.6	2.9
HDL Cholesterol	0.7	1.1	3.5	-0.5	-0.2	-0.0	0.3	-1.4	-1.2	-1.7	-1.8	0.0	-0.6	-1.0	-0.4	-1.2	-0.8	-0.7	-1.4	-1.6	0.1	-1.9	-0.4	-0.6	-0.7	-0.2	-0.7	-1.7	1.5
LDL Cholesterol	0.7	1.1	2.7	-1.2	-1.1	-1.2	-1.1	-1.0	-1.6	-1.0	-1.3	-0.5	-1.2	-0.8	-1.2	-1.0	-1.2	-1.2	-1.1	-1.2	-0.7	-0.9	-0.5	-1.0	-0.7	-0.9	-1.1	-1.3	0.2
Height	0.7	12.8	33.8	-3.9	-2.2	-3.0	-3.2	-4.2	-4.5	-4.2	-5.8	-1.5	-4.0	-4.1	-4.0	-4.3	-4.2	-4.1	-3.6	-4.9	3.9	-0.1	-1.1	-1.2	-5.2	-2.4	-3.2	-0.6	1.6
Hand grip strength (left)	0.7	1.7	6.2	-1.3	-0.4	-0.8	-0.8	-1.6	-1.4	-1.9	-2.0	0.1	-1.3	-1.1	-1.2	-1.6	-1.4	-1.3	-1.2	-1.9	2.5	0.5	-0.0	0.3	-2.1	-1.3	-0.8	0.3	1.0
Leg fat-free mass (left)	0.7	3.9	10.0	1.8	2.6	2.3	2.3	1.0	1.6	0.2	0.7	2.9	1.8	1.4	1.9	1.1	1.6	1.7	1.3	0.8	3.2	2.1	2.5	3.0	0.9	1.1	2.2	2.3	2.9
Leg predicted mass (left)	0.7	3.7	9.2	1.8	2.5	2.2	2.2	1.0	1.6	0.2	0.6	2.8	1.7	1.4	1.8	1.1	1.6	1.7	1.3	0.8	3.0	2.0	2.4	2.9	0.9	1.1	2.1	2.3	2.9
Hearing difficulty/problems with background noise	0.7	1.1	4.6	1.2	1.0	1.4	1.8	0.4	1.6	-0.3	0.5	2.1	1.2	0.4	1.1	0.5	1.1	1.1	0.3	0.7	0.5	-0.8	1.2	0.6	0.9	0.1	0.9	-0.4	1.5
Financial difficulties in last 2 years	0.7	0.9	1.6	1.1	1.0	1.0	0.8	1.1	0.8	0.7	1.2	0.9	1.1	0.9	1.3	1.1	1.2	1.1	1.1	1.2	0.2	0.9	0.4	0.8	0.9	0.4	1.0	1.0	0.6
Time employed in main current job	0.7	0.8	2.2	-0.7	-0.7	-0.5	-0.4	-1.1	-0.9	-0.6	-0.7	0.1	-0.8	-1.1	-0.8	-1.0	-0.9	-0.8	-1.2	-1.1	-0.2	-1.5	-0.0	-1.1	-0.2	-1.4	-1.0	-1.2	-1.3
Falls in the last year	0.7	0.9	3.8	-1.1	-0.8	-1.2	-1.8	-0.2	-0.4	0.8	-0.3	-1.6	-1.1	-0.7	-1.0	-0.4	-0.8	-1.0	-0.1	-0.1	0.4	1.5	0.0	-0.3	-0.8	-1.0	-0.8	0.4	-1.9
Number of live births	0.7	0.9	2.7	0.6	0.3	0.1	-0.1	1.3	0.6	1.3	1.6	-0.2	0.7	1.2	0.7	1.2	0.8	0.7	1.4	1.1	-0.1	1.6	-0.1	0.7	0.7	1.1	0.7	1.6	-1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.5	6.0	0.1	0.4	0.8	1.2	-1.4	-0.4	-2.5	-1.9	0.6	-0.1	-0.7	-0.1	-1.2	-0.4	-0.2	-1.4	-1.2	2.3	-1.8	0.5	0.0	-1.2	-0.6	-0.3	-1.6	2.4
Mouth/teeth dental problems: Dentures	0.7	1.2	1.8	1.1	1.1	1.1	0.8	1.1	1.3	0.8	0.8	1.3	1.1	1.1	1.3	1.1	1.2	1.1	1.1	1.2	1.3	1.3	1.1	1.1	0.7	0.6	1.1	1.2	1.1
Hair/balding pattern: Pattern 4	0.7	1.8	6.9	-1.5	-1.6	-1.5	-1.6	-1.2	-1.2	-0.2	-1.0	-2.6	-1.4	-1.2	-1.6	-1.3	-1.3	-1.4	-1.2	-1.0	-0.5	-1.0	-0.8	-1.5	-0.8	-0.9	-1.5	-1.2	-1.7
Comparative body size at age 10	0.7	2.0	4.2	1.3	1.4	1.2	1.0	1.4	2.0	1.3	1.6	1.0	1.3	1.4	1.4	1.4	1.5	1.4	1.6	1.9	1.1	2.0	1.7	1.7	0.7	0.3	1.5	1.8	-0.0
Eye problems/disorders: None of the above	0.7	0.9	1.8	-0.8	-0.8	-0.6	-0.5	-1.0	-1.1	-1.2	-1.0	-0.4	-0.8	-0.6	-0.9	-1.0	-0.9	-0.8	-1.0	-1.1	-0.8	-1.0	-1.3	-0.9	-1.3	-1.3	-0.9	-1.0	0.1
Number of full sisters	0.7	0.8	3.2	0.6	0.1	0.0	-0.2	1.4	1.1	1.2	1.8	-0.2	0.7	0.7	0.7	1.3	0.9	0.8	1.4	1.2	-0.9	1.2	-0.8	0.2	0.5	0.4	0.6	1.0	-0.9
Illnesses of father: Heart disease	0.7	0.9	4.9	0.6	1.1	1.3	1.4	-0.4	0.4	-1.5	-0.8	1.5	0.5	0.5	0.6	-0.3	0.3	0.4	-0.4	-0.4	2.2	-0.6	0.7	0.8	-0.9	-0.2	0.5	-0.5	1.9
Diastolic blood pressure, automated reading	0.7	2.1	9.6	1.7	1.9	2.0	2.2	0.9	0.8	-0.0	1.7	3.1	1.6	1.1	1.6	1.0	1.3	1.5	0.9	-0.2	1.2	0.3	1.8	1.6	1.5	-0.4	1.6	0.5	0.8
Cholesterol lowering medication	0.7	1.0	2.0	0.9	1.0	0.8	0.6	1.1	0.7	1.3	1.2	0.9	0.9	0.6	0.8	1.1	0.9	0.9	1.1	1.0	1.0	1.4	1.4	1.1	1.3	0.3	1.0	1.3	-0.2
Supplements: Calcium	0.7	0.8	2.0	-1.0	-1.0	-1.0	-1.1	-0.8	-1.1	-0.5	-1.0	-1.0	-1.0	-0.7	-1.1	-0.9	-1.0	-1.0	-0.7	-0.7	0.0	-0.1	-0.9	-0.7	-1.4	-0.8	-0.9	-0.2	-0.5
Crohns Disease (2012)	0.6	1.0	4.4	0.5	0.3	-0.1	-0.3	1.4	0.8	1.6	2.1	-0.3	0.6	0.5	0.8	1.3	0.8	0.7	1.4	1.1	-1.3	1.3	0.2	0.3	0.3	-0.5	0.6	1.0	-2.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.6	0.8	0.3	0.4	0.4	1.2	0.8	1.5	1.6	-0.0	0.9	1.1	0.7	1.2	1.0	0.9	1.1	1.5	-0.4	0.5	0.4	0.3	1.2	0.7	0.7	0.4	-0.9
Current tobacco smoking	0.6	1.0	4.7	0.3	0.0	-0.1	-0.6	1.2	0.5	1.7	1.6	-0.4	0.3	0.8	0.4	1.1	0.6	0.4	1.3	1.2	0.3	2.2	-0.2	0.6	0.4	-0.2	0.5	1.8	-1.7
High blood pressure	0.6	1.7	5.2	1.6	1.8	2.0	2.3	0.6	0.8	-0.2	0.7	2.2	1.5	0.9	1.6	0.7	1.2	1.4	0.5	0.4	0.9	-0.5	1.4	1.2	1.3	0.9	1.4	-0.0	1.9
Sitting height	0.6	4.4	10.6	-2.4	-1.2	-1.8	-2.1	-2.4	-2.7	-2.3	-3.2	-0.9	-2.5	-2.1	-2.4	-2.4	-2.5	-2.5	-1.9	-2.7	2.3	0.8	-0.9	-0.3	-3.3	-1.9	-1.7	0.4	0.7
Pulse rate	0.6	1.1	6.7	-0.6	-0.6	-0.3	-0.4	-1.0	-2.0	-1.1	-0.2	0.7	-0.7	-0.5	-0.7	-1.0	-1.0	-0.7	-0.9	-2.3	0.2	-0.7	-0.5	-0.6	-0.5	-2.6	-0.8	-0.3	-1.0
Wheeze or whistling in the chest in last year	0.6	1.0	2.5	0.9	0.9	0.8	0.5	1.2	1.0	1.2	1.2	1.6	0.9	1.2	1.0	1.2	1.0	1.0	1.2	1.0	0.5	1.5	1.3	1.0	0.8	0.3	0.9	1.0	0.1
Shortness of breath walking on level ground	0.6	0.7	2.5	0.8	1.2	1.3	1.6	-0.2	0.5	-0.3	-0.0	1.4	0.8	0.1	0.7	-0.1	0.5	0.7	-0.1	0.1	1.4	-0.7	1.4	0.8	1.1	0.1	0.7	-0.7	1.2
Medication: Blood pressure	0.6	1.0	5.5	-0.4	-0.5	-0.1	0.3	-1.2	-0.8	-1.3	-1.0	-0.3	-0.5	-1.0	-0.4	-1.1	-0.7	-0.6	-1.4	-1.1	-1.0	-2.3	-0.2	-1.2	-0.1	-0.6	-0.8	-2.1	0.1
Heart disease (mother)	0.6	0.8	3.2	-0.6	-1.0	-0.4	-0.3	-0.9	-0.2	-0.9	-1.0	-1.0	-0.6	-0.6	-0.5	-0.8	-0.7	-0.6	-1.1	-0.8	-0.6	-1.8	-0.6	-1.4	-0.6	-0.1	-1.0	-1.7	-0.1
Arm predicted mass (right)	0.6	3.1	16.6	1.1	2.3	1.7	1.6	0.4	0.8	-0.2	0.3	2.6	1.1	1.1	1.1	0.5	0.9	1.0	1.0	0.2	4.1	2.9	2.7	3.1	0.0	0.2	1.8	2.7	1.9
Hypertension (Self-reported)	0.6	1.8	4.7	1.7	1.9	1.9	2.2	0.8	1.1	0.2	0.9	2.1	1.6	1.0	1.7	0.9	1.4	1.5	0.7	0.7	0.6	-0.3	1.4	1.2	1.6	0.9	1.4	0.2	1.6
Whole body fat-free mass	0.6	3.5	18.0	1.3	2.5	2.0	2.0	0.3	1.1	-0.5	-0.1	2.8	1.3	0.9	1.4	0.4	1.1	1.2	0.9	0.2	4.2	2.4	2.8	3.1	-0.1	0.4	1.8	2.3	3.0
Medication: Aspirin	0.6	0.8	2.3	0.6	0.2	0.2	-0.0	1.2	1.1	1.5	1.3	0.1	0.7	0.8	0.7	1.1	0.8	0.8	1.1	1.2	-1.4	0.9	-0.1	0.1	1.4	0.4	0.5	0.8	0.0
Smoking status: Current	0.6	1.0	5.0	0.3	0.1	-0.0	-0.5	1.2	0.4	1.7	1.6	-0.2	0.4	0.8	0.4	1.1	0.6	0.5	1.3	1.1	0.4	2.2	0.0	0.8	0.6	-0.3	0.6	1.9	-1.6
Whole body water mass	0.6	3.6	17.8	1.4	2.5	2.1	2.0	0.4	1.2	-0.4	-0.1	2.9	1.3	1.0	1.4	0.5	1.1	1.2	0.9	0.3	4.2	2.4	2.8	3.1	-0.1	0.5	1.9	2.4	3.0
Schizophrenia (2014)	0.5	1.1	3.2	0.7	0.1	0.2	0.0	1.5	0.4	1.5	1.8	-0.2	0.9	1.6	0.7	1.4	1.0	1.0	1.4	0.9	-1.3	0.9	-0.8	0.2	0.8	1.2	0.7	1.4	-0.8
Lung FVC	0.5	2.3	5.5	-1.6	-0.9	-1.1	-1.2	-1.9	-1.8	-2.0	-1.9	-0.8	-1.7	-2.1	-1.4	-1.8	-1.9	-1.7	-1.7	-2.4	0.7	-0.5	-0.6	-0.7	-2.1	-1.7	-1.4	-0.9	-0.5
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.4	-0.9	-0.4	-0.8	-0.7	-1.0	-1.0	-0.6	-0.9	-0.3	-0.9	-1.2	-1.0	-1.0	-0.9	-1.0	-0.9	-0.9	-0.2	-0.3	-0.3	-0.4	-1.0	-1.5	-0.8	-0.9	-0.2
Medication for hormone replacement therapy	0.5	0.6	2.0	-0.9	-0.7	-1.1	-1.4	-0.1	-0.3	0.2	-0.2	-0.7	-0.8	-0.6	-0.6	-0.3	-0.7	-0.8	-0.0	-0.1	-1.1	1.0	-0.7	-0.4	-1.3	-0.8	-0.6	0.7	-1.0
Maternal smoking around birth	0.5	0.8	6.5	-0.4	-0.7	-0.9	-1.1	0.6	-0.1	1.3	1.2	-1.1	-0.2	0.2	-0.3	0.4	0.0	-0.2	0.5	0.8	-1.5	0.6	-0.3	-0.5	0.3	-1.1	-0.3	0.0	-2.5
Number of incorrect matches in round	0.5	0.9	2.3	0.8	0.4	0.3	0.1	1.4	0.8	1.5	1.3	-0.0	0.8	0.9	0.6	1.2	1.0	0.9	1.4	1.5	0.7	1.4	1.0	0.6	1.0	0.5	0.8	1.1	-0.5
Medication: Ramipril	0.5	0.6	2.8	-0.3	-0.5	0.0	0.2	-0.9	-0.5	-1.1	-0.7	-0.7	-0.4	-0.8	-0.5	-0.9	-0.6	-0.4	-1.1	-1.0	0.0	-1.7	-0.4	-0.9	-0.8	-0.9	-0.7	-1.5	-0.2
Trunk fat-free mass	0.5	3.1	21.8	0.8	2.1	1.7	1.6	-0.3	0.6	-1.2	-0.9	2.6	0.7	0.3	0.8	-0.2	0.5	0.6	0.3	-0.4	4.7	2.2	2.8	2.8	-0.9	-0.1	1.4	1.9	3.0
Noisy workplace	0.5	0.6	1.3	0.9	0.3	0.6	0.6	1.1	0.7	0.9	1.1	0.6	0.9	0.6	0.9	1.1	0.9	0.9	0.9	0.9	-0.9	0.0	-0.1	0.0	1.0	0.9	0.6	0.2	0.1
Trunk predicted mass	0.5	3.0	22.1	0.8	2.1	1.7	1.6	-0.4	0.5	-1.2	-0.9	2.6	0.7	0.3	0.8	-0.3	0.4	0.6	0.2	-0.4	4.7	2.1	2.8	2.8	-1.0	-0.2	1.3	1.9	3.0
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.8	-0.0	-0.7	-0.0	0.0	-0.2	0.5	-0.0	-0.0	-0.4	-0.1	-0.5	0.2	-0.2	-0.0	-0.1	-0.5	-0.2	-1.9	-1.9	-0.6	-1.3	1.1	-0.2	-0.6	-1.5	-0.2
Alcohol intake frequency.	0.5	1.1	4.5	-1.0	-1.2	-1.4	-1.4	-0.4	-0.9	0.1	-0.1	-1.3	-1.0	-0.7	-1.1	-0.5	-0.9	-0.9	-0.5	-0.3	-2.1	-0.5	-1.6	-1.2	-0.6	-0.9	-1.0	-0.5	-1.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.6	0.8	1.0	1.2	1.4	-0.2	0.4	-0.5	-0.4	1.3	0.7	0.8	0.8	-0.0	0.5	0.6	-0.1	-0.0	1.0	-0.4	1.6	0.8	0.2	0.0	0.6	-0.4	1.6
Supplements: Vitamin C	0.5	0.5	2.2	-0.8	-0.9	-1.0	-0.9	-0.4	-0.9	0.0	-0.0	-1.5	-0.8	-0.4	-0.9	-0.5	-0.7	-0.8	-0.4	-0.5	-0.4	-0.2	-1.2	-0.5	-0.2	-0.6	-0.6	-0.2	-1.1
Hearing aid user	0.5	0.5	2.6	0.1	-0.2	-0.4	-0.5	1.0	0.2	1.6	1.2	-0.7	0.2	0.3	0.2	0.8	0.4	0.3	0.9	0.7	-1.4	0.9	0.0	-0.0	0.9	0.2	0.2	0.7	-1.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.4	-0.8	-0.5	-0.7	-0.5	-0.9	-0.7	-0.9	-0.9	-0.5	-0.8	-1.1	-0.8	-0.9	-0.7	-0.8	-0.9	-0.6	-0.1	-1.1	-0.0	-0.6	-0.5	-0.8	-0.7	-1.2	-0.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.0	0.6	0.2	0.3	0.1	1.1	0.7	1.3	1.4	-0.2	0.7	0.6	0.5	1.0	0.9	0.8	1.0	1.2	-0.8	0.7	0.5	0.1	0.7	-0.1	0.5	0.7	-0.9
Ever had prostate specific antigen (PSA) test	0.5	0.5	4.2	0.2	-0.1	0.5	0.9	-0.7	-0.1	-1.1	-0.7	-0.0	0.1	-0.8	0.1	-0.6	-0.1	0.0	-0.9	-0.6	-0.2	-2.0	0.2	-0.4	-0.3	-0.8	-0.2	-1.6	1.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.6	-0.6	-1.1	-1.1	-1.2	0.2	-0.1	0.9	0.2	-1.1	-0.6	-0.4	-0.6	0.1	-0.4	-0.5	0.1	0.3	-1.6	0.0	-1.3	-0.9	-0.1	0.1	-0.7	0.1	-1.4
Depression (Nagel 2018)	0.4	0.6	1.2	-0.6	-0.5	-0.5	-0.5	-0.8	-0.8	-0.6	-0.7	-0.1	-0.7	-0.9	-0.7	-0.8	-0.7	-0.7	-0.8	-0.8	-1.0	-0.9	-0.8	-0.9	-0.7	-1.1	-0.8	-1.0	-0.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	5.0	-0.2	0.6	0.5	0.9	-1.5	-0.0	-2.2	-1.4	0.5	-0.3	-0.8	-0.3	-1.3	-0.6	-0.5	-1.4	-1.4	1.6	-1.9	0.9	-0.0	-1.2	-1.5	-0.4	-1.7	1.2
Schizophrenia (2018)	0.4	0.8	3.0	0.3	-0.3	-0.2	-0.4	1.2	0.3	1.4	1.7	-0.4	0.5	1.4	0.4	1.1	0.7	0.6	1.1	0.7	-1.6	0.8	-0.9	-0.2	0.9	0.5	0.3	1.1	-1.4
Crohns Disease (2017)	0.4	0.9	6.7	-0.6	-0.7	-1.0	-1.0	0.1	-0.5	0.4	0.9	-0.6	-0.4	-0.8	-0.3	0.0	-0.4	-0.4	0.0	-0.3	-2.3	-0.3	-0.7	-1.0	-0.3	-1.5	-0.6	-0.5	-2.6
Fasting Glucose	0.4	0.5	4.4	-0.6	-0.9	-0.9	-0.9	-0.1	-0.0	0.4	-0.1	-1.1	-0.4	0.0	-0.4	-0.2	-0.3	-0.4	-0.0	0.2	-2.1	-0.4	-1.4	-0.9	0.2	0.6	-0.6	-0.0	-0.1
Systolic Blood Pressure	0.4	1.8	5.5	1.6	1.2	1.9	2.3	0.4	1.3	-0.5	0.5	2.4	1.5	0.8	1.5	0.6	1.2	1.4	0.1	0.4	0.7	-1.8	-0.0	0.3	1.9	1.8	0.9	-0.9	2.1
Neuroticism	0.4	1.0	1.8	-1.1	-0.7	-1.0	-0.9	-1.1	-1.2	-0.6	-1.2	-1.1	-1.1	-1.2	-1.2	-1.1	-1.1	-1.1	-1.0	-1.0	-0.8	-0.7	-0.6	-0.8	-1.3	-0.7	-0.9	-1.3	-0.7
Chronotype (morning person)	0.4	1.0	6.1	-0.2	0.6	0.4	0.6	-1.2	-0.1	-1.3	-1.5	1.2	-0.4	-0.8	-0.3	-1.1	-0.6	-0.5	-1.1	-1.3	2.5	-0.6	1.8	0.5	-0.6	-0.5	-0.1	-1.1	1.1
Medication: Metformin	0.4	0.6	1.7	0.7	0.8	0.7	0.7	0.6	0.7	1.0	0.8	0.4	0.7	0.7	0.7	0.7	0.6	0.7	0.7	1.0	0.3	0.8	1.1	0.9	1.3	0.8	0.8	0.7	0.1
Diabetes (mother)	0.4	0.5	4.1	-0.1	-0.8	-0.5	-0.6	0.5	-0.2	1.0	0.9	-1.0	-0.0	0.2	-0.1	0.5	0.1	0.0	0.4	0.6	-2.0	0.1	-1.4	-0.7	0.6	-0.4	-0.2	0.3	-1.1
Fed-up feelings	0.4	0.7	2.1	-0.8	-0.9	-0.9	-0.8	-0.7	-1.4	-0.4	-0.5	-1.4	-0.8	-1.1	-1.0	-0.7	-0.8	-0.8	-0.7	-0.7	-0.4	-0.5	-0.6	-0.6	-0.8	-0.8	-0.7	-1.0	-0.9
High blood pressure (mother)	0.4	0.6	3.4	-0.4	-0.9	-0.6	-0.2	-0.5	-0.4	-0.4	-0.3	-0.7	-0.4	-1.0	-0.4	-0.5	-0.4	-0.4	-0.7	-0.5	-1.3	-1.9	-1.4	-1.3	0.6	0.2	-0.7	-1.2	0.2
Alcohol usually taken with meals	0.4	0.6	2.2	-0.6	-0.7	-0.3	-0.0	-1.1	-0.6	-1.2	-1.2	-0.3	-0.6	-0.9	-0.6	-1.0	-0.7	-0.7	-1.1	-1.1	-0.1	-1.5	-0.5	-0.8	-0.3	-0.3	-0.8	-1.3	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.5	-1.1	-1.1	-1.3	-1.4	-0.7	-0.3	-0.8	-0.7	-1.1	-1.1	-0.8	-1.1	-0.8	-1.0	-1.1	-0.7	-0.6	-1.5	-0.3	-1.3	-1.1	-1.6	-0.8	-1.1	-0.6	-0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.2	-0.8	-0.7	-0.9	-1.1	-0.3	-1.0	0.2	-0.2	-0.8	-0.7	-0.7	-0.8	-0.4	-0.6	-0.7	-0.3	-0.3	0.4	0.4	-0.3	-0.4	-0.4	-1.0	-0.6	0.0	-1.1
Diabetes (self-reported)	0.4	0.7	1.8	0.7	0.7	0.5	0.4	0.9	1.0	1.1	0.9	0.6	0.7	0.8	0.7	0.9	0.8	0.8	0.9	1.4	0.1	1.0	0.9	0.7	1.1	0.9	0.8	0.7	-0.0
Fluid intelligence score	0.4	0.8	2.3	-0.9	-0.2	-0.6	-0.8	-1.0	-1.3	-0.7	-0.8	-0.6	-1.0	-0.7	-1.0	-1.0	-1.1	-1.0	-0.8	-1.2	0.5	0.3	0.2	-0.2	-1.5	-1.5	-0.7	-0.3	-1.1
Medication: Cholesterol lowering	0.4	0.6	1.8	-0.6	-0.4	-0.4	-0.2	-1.0	-0.4	-1.2	-1.1	0.2	-0.7	-0.8	-0.6	-1.0	-0.7	-0.7	-1.0	-0.8	0.1	-1.0	-0.0	-0.6	-1.2	-0.7	-0.7	-1.3	0.4
Depression (self-reported)	0.4	0.4	3.5	0.3	0.6	0.7	0.7	-0.3	-0.1	-0.9	-0.7	1.2	0.3	0.1	0.2	-0.2	0.3	0.2	-0.1	-0.2	1.5	0.0	0.3	0.6	-0.5	-0.2	0.3	-0.3	1.9
Illnesses of mother	0.4	0.6	3.3	-0.5	0.1	-0.3	-0.4	-0.5	-0.6	-0.6	-0.2	-0.2	-0.5	-0.5	-0.6	-0.5	-0.5	-0.5	-0.2	-0.5	1.2	1.1	0.7	0.7	-1.8	-1.8	-0.1	0.3	-0.9
Exposure to tobacco smoke at home	0.4	0.4	1.1	0.4	0.2	0.1	0.1	0.8	1.0	1.0	0.9	0.3	0.5	0.7	0.5	0.8	0.7	0.5	0.8	0.9	0.6	1.0	0.8	0.5	0.5	0.1	0.5	0.7	-0.4
Blood clot in the leg (DVT)	0.4	0.5	2.1	-0.5	-0.9	-1.0	-1.1	0.2	-0.1	0.9	0.2	-1.1	-0.5	-0.2	-0.5	0.1	-0.3	-0.4	0.1	0.3	-1.5	0.1	-1.3	-0.8	-0.2	0.2	-0.5	0.2	-1.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.3	-0.6	-0.2	-0.4	-0.4	-0.8	-0.1	-1.2	-0.9	0.4	-0.6	-0.8	-0.6	-0.8	-0.8	-0.7	-0.8	-0.8	0.1	-0.4	-0.0	-0.3	-0.8	-1.1	-0.6	-1.1	0.2
Medication for pain relief, constipation, heartburn	0.4	0.7	1.5	-0.9	-0.5	-0.6	-0.5	-1.2	-1.2	-1.2	-1.2	-0.3	-0.9	-1.1	-0.9	-1.1	-1.0	-1.0	-1.1	-1.2	0.1	-0.8	-0.1	-0.4	-0.9	-0.9	-0.7	-0.7	0.1
Mean time to correctly identify matches	0.4	0.7	1.8	1.0	0.3	0.6	0.5	1.3	0.5	1.2	0.9	0.4	1.0	0.9	0.8	1.3	1.1	1.1	1.2	0.9	0.2	0.5	0.3	0.3	0.4	1.0	0.7	1.1	0.6
Comparative height size at age 10	0.4	2.4	9.5	-1.3	-0.3	-0.6	-0.7	-1.9	-1.8	-2.1	-2.8	-0.2	-1.4	-1.2	-1.3	-1.9	-1.6	-1.5	-1.5	-2.1	3.1	0.3	-0.2	0.1	-2.5	-0.6	-1.0	0.3	1.6
Chest pain or discomfort	0.4	0.6	1.8	0.7	0.6	0.5	0.4	1.0	0.8	0.7	1.3	1.2	0.8	0.8	0.9	1.0	0.8	0.8	0.9	1.0	-0.9	0.2	0.3	0.3	0.8	-0.2	0.6	-0.0	-0.2
Knee pain experienced in last month	0.4	0.6	1.3	0.7	0.9	0.6	0.5	0.8	1.1	0.6	0.2	0.8	0.7	0.3	0.7	0.8	0.8	0.7	0.8	0.8	0.7	0.9	1.1	0.7	0.0	1.1	0.7	0.6	1.0
Handedness (chirality/laterality): Left-handed	0.4	0.4	3.7	0.1	0.6	0.0	-0.1	0.4	0.3	0.4	0.4	0.4	0.1	0.4	0.2	0.3	0.2	0.1	0.6	0.2	1.9	1.6	0.7	1.0	-0.3	-0.3	0.5	1.2	-0.0
Loneliness, isolation	0.4	0.5	2.4	0.4	0.8	0.2	0.1	0.7	0.5	1.1	0.6	0.6	0.4	0.1	0.4	0.7	0.5	0.4	0.9	0.8	0.5	1.6	0.9	1.0	0.4	0.7	0.7	1.1	0.2
Medication for cholesterol	0.4	0.5	3.3	-0.1	-0.6	0.2	0.3	-0.8	-0.5	-1.1	-0.9	-0.5	-0.2	-0.5	-0.1	-0.7	-0.3	-0.2	-0.9	-0.7	-0.2	-1.8	-0.5	-0.9	-0.5	-0.3	-0.6	-1.8	0.5
Back pain experienced in last month	0.4	0.5	2.1	0.2	0.0	-0.1	-0.4	0.8	-0.2	1.5	1.3	-0.6	0.2	0.4	0.1	0.7	0.4	0.3	0.9	0.7	0.5	1.5	0.4	0.4	0.6	-0.1	0.4	1.0	-1.4
Miserableness	0.4	0.6	2.7	0.5	0.7	0.4	0.2	0.9	0.3	1.0	0.7	0.2	0.6	0.8	0.3	0.8	0.6	0.6	1.0	0.9	0.8	1.7	0.8	1.1	0.1	0.6	0.8	1.5	0.3
Fractured/broken bones in last 5 years	0.4	0.5	1.7	0.8	0.8	0.7	0.9	0.6	0.6	0.5	0.9	1.1	0.8	0.5	0.7	0.7	0.7	0.7	0.6	0.5	0.4	0.4	1.1	0.9	1.3	0.3	0.9	0.5	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.8	-1.3	-1.6	-1.7	-2.0	-0.2	-0.6	0.5	-0.3	-2.2	-1.2	-0.6	-1.2	-0.4	-0.9	-1.1	-0.2	-0.1	-1.0	0.5	-1.3	-1.1	-1.0	-0.5	-1.1	0.1	-1.8
Prostate Cancer	0.3	0.4	1.5	0.8	0.4	1.1	1.2	-0.0	0.1	-0.2	0.4	0.9	0.7	0.5	0.6	0.1	0.4	0.6	-0.1	-0.2	0.3	-0.9	0.7	0.2	1.1	-0.2	0.4	-0.9	0.6
Coronary Artery Disease (CAD)	0.3	0.3	3.3	0.1	0.6	0.5	0.7	-0.5	-0.2	-1.2	-0.1	1.8	0.2	0.2	0.1	-0.5	0.1	0.1	-0.3	-0.6	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.3	0.5	2.0	0.2	-0.1	-0.3	-0.5	0.9	0.3	1.4	1.0	-0.4	0.3	0.7	0.2	0.8	0.4	0.3	0.9	0.8	-1.3	1.0	-0.4	0.0	0.6	0.3	0.2	0.8	-0.8
Number of treatments/medications taken	0.3	0.6	1.8	0.9	0.6	1.0	1.1	0.4	0.8	0.3	0.4	1.0	0.9	0.5	0.8	0.5	0.8	0.9	0.3	0.6	0.0	-0.7	0.9	0.1	1.4	0.6	0.5	-0.6	1.1
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.3	0.4	0.3	0.2	0.0	0.8	0.5	1.1	0.9	0.2	0.4	0.5	0.4	0.7	0.5	0.5	0.8	0.7	-0.4	1.0	0.5	0.4	1.1	0.1	0.5	0.6	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.9	-0.7	-0.8	-0.9	-0.9	-0.5	0.1	-0.7	-0.8	-1.0	-0.7	-0.7	-0.7	-0.5	-0.6	-0.7	-0.6	-0.3	-1.4	-0.7	-1.1	-1.0	-1.1	-0.4	-0.8	-0.8	0.2
Serious illness, injury or assault to yourself	0.3	0.4	2.4	0.2	-0.2	-0.3	-0.3	0.8	0.2	1.1	0.9	0.5	0.3	0.2	0.2	0.7	0.4	0.3	0.7	0.5	-1.6	0.2	-0.5	-0.2	1.1	0.5	0.2	0.6	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.3	-0.7	-0.7	-0.8	-0.9	-0.3	-1.5	0.3	-0.0	-1.5	-0.7	-0.6	-0.7	-0.4	-0.6	-0.6	-0.3	-0.5	-0.3	0.1	-0.9	-0.5	-0.7	-0.5	-0.5	-0.1	-1.4
Hair/balding pattern: Pattern 2	0.3	0.4	2.1	0.5	0.8	0.5	0.3	0.7	-0.2	0.7	0.5	0.6	0.5	0.6	0.5	0.6	0.5	0.5	0.8	0.2	0.3	1.4	0.3	1.1	0.1	0.7	0.8	1.0	0.5
Had other major operations	0.3	0.4	1.2	-0.5	-1.0	-0.6	-0.6	-0.3	-0.1	-0.1	-0.6	-0.8	-0.5	-0.5	-0.7	-0.4	-0.4	-0.4	-0.5	-0.1	-0.8	-0.8	-0.8	-1.1	-0.2	0.6	-0.8	-0.7	0.2
Heart attack	0.3	0.3	1.0	0.6	0.4	0.6	0.6	0.5	1.0	0.6	0.5	0.5	0.6	0.7	0.7	0.5	0.7	0.6	0.4	0.8	-0.7	-0.1	0.3	0.3	0.8	0.4	0.5	0.1	0.5
Pain all over the body in last month	0.3	0.3	1.0	0.4	0.2	0.1	0.3	0.7	0.7	0.9	0.9	0.2	0.5	0.5	0.5	0.6	0.5	0.5	0.5	0.6	-1.0	-0.3	-0.1	-0.1	1.0	0.6	0.3	-0.0	-0.5
Medication: Simvastatin	0.3	0.5	1.2	-0.5	-0.3	-0.1	-0.1	-1.1	-0.4	-0.9	-1.0	0.3	-0.6	-0.8	-0.5	-1.0	-0.7	-0.6	-1.0	-0.8	0.3	-1.1	0.3	-0.6	-0.2	-1.1	-0.7	-1.0	0.2
Illnesses of siblings	0.3	0.5	1.3	0.6	0.3	0.4	0.3	0.9	1.0	1.2	0.7	-0.5	0.7	0.8	0.7	0.8	0.8	0.7	0.9	1.0	-0.2	0.8	-0.1	0.4	0.2	0.8	0.6	0.9	-0.1
Father’s age at death	0.3	0.4	1.3	-0.4	-0.1	-0.1	0.1	-0.9	-0.0	-1.1	-0.7	0.0	-0.5	-0.5	-0.4	-0.8	-0.6	-0.5	-0.9	-0.6	0.5	-0.9	0.4	-0.3	-0.7	-1.1	-0.5	-1.0	-0.2
Lung cancer (father)	0.3	0.3	1.1	0.2	-0.2	-0.2	-0.4	0.8	0.1	0.8	0.8	-0.5	0.3	0.0	0.3	0.7	0.3	0.3	0.8	0.6	-0.5	0.8	-1.0	0.1	-0.1	0.8	0.2	1.0	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.9	-0.5	-0.8	-0.5	-0.5	-0.5	-0.4	-0.3	-0.6	-0.5	-0.5	-0.4	-0.6	-0.6	-0.5	-0.5	-0.6	-0.5	-0.7	-0.9	-1.4	-0.9	-0.2	-0.1	-0.7	-0.9	-0.2
Headache pain in last month	0.3	0.5	1.5	-0.6	-0.8	-0.7	-0.5	-0.7	-0.7	-0.6	-0.8	-0.4	-0.7	-0.5	-0.6	-0.7	-0.7	-0.7	-0.9	-0.7	-0.6	-1.2	-0.4	-1.1	-0.2	-0.0	-0.9	-1.2	-0.1
Exposure to tobacco smoke outside home	0.3	0.4	1.7	-0.8	-0.8	-1.1	-1.1	-0.3	-0.7	0.2	-0.4	-0.3	-0.7	-0.4	-0.8	-0.3	-0.7	-0.7	-0.3	-0.4	-1.3	-0.1	-0.6	-0.7	-0.3	-0.8	-0.7	-0.6	-0.4
Pulse wave peak to peak time	0.3	0.3	0.9	-0.4	-0.3	-0.2	-0.2	-0.6	-0.6	-0.7	-0.4	-0.8	-0.5	-0.1	-0.2	-0.6	-0.4	-0.5	-0.7	-0.5	-0.6	-0.6	-0.9	-0.5	-0.6	-0.8	-0.5	-0.6	-0.5
Emphysema/chronic bronchitis	0.3	0.3	0.8	0.4	0.1	0.1	0.0	0.7	0.9	0.8	0.7	0.4	0.4	0.3	0.4	0.6	0.5	0.4	0.7	0.8	0.1	0.8	0.6	0.4	0.8	-0.2	0.3	0.5	0.4
Medication: Ibuprofen	0.3	0.3	0.8	0.5	0.3	0.3	0.2	0.6	0.7	0.9	0.7	-0.3	0.5	0.6	0.4	0.6	0.6	0.5	0.7	0.8	0.3	0.9	0.3	0.4	0.6	0.6	0.4	0.7	-0.3
Medication: Aspirin	0.3	0.4	1.4	0.2	-0.0	-0.2	-0.4	0.9	0.8	1.2	0.9	-0.1	0.3	0.4	0.3	0.7	0.5	0.4	0.8	1.0	-1.0	0.9	-0.3	-0.0	0.9	0.4	0.2	0.7	-0.2
Eye problems/disorders: Cataract	0.3	0.3	1.2	0.4	0.4	0.3	0.1	0.6	0.2	0.9	0.8	0.2	0.4	0.3	0.4	0.5	0.4	0.4	0.6	0.5	0.5	1.1	0.7	0.5	0.3	0.5	0.5	1.0	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.8	-0.5	-0.3	-0.4	-0.4	-0.6	-0.8	-1.0	-1.2	-0.5	-0.5	-0.4	-0.5	-0.6	-0.6	-0.5	-0.6	-0.7	0.5	-0.4	-0.3	-0.3	-1.3	0.7	-0.5	-0.4	0.8
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	-0.1	-0.3	-0.5	-0.7	0.7	0.2	1.2	0.8	-0.6	0.0	0.3	0.1	0.6	0.2	0.1	0.7	0.5	-0.8	1.1	-0.4	0.0	0.0	0.4	0.1	1.2	-1.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.6	-0.3	-0.7	-0.4	-0.4	-0.3	-0.1	-0.4	-0.5	-0.9	-0.3	-0.4	-0.3	-0.3	-0.3	-0.3	-0.5	-0.2	-0.9	-1.2	-0.7	-1.2	-0.5	-0.1	-0.7	-1.1	-0.2
Average weekly beer plus cider intake	0.3	0.5	2.5	-0.6	-0.8	-0.7	-0.6	-0.4	-1.0	0.2	-0.3	-0.9	-0.6	-0.6	-0.6	-0.4	-0.5	-0.6	-0.5	-0.5	-1.6	-0.9	-0.7	-0.9	0.4	-0.1	-0.7	-0.5	-0.7
Age started oral contraceptive pill	0.3	0.4	1.0	0.5	0.3	0.4	0.2	0.7	0.7	0.7	0.6	-0.2	0.5	0.8	0.4	0.7	0.6	0.6	0.8	0.6	0.4	1.0	0.5	0.5	0.7	0.8	0.5	0.8	0.2
Unable to work because of sickness or disability	0.3	0.3	1.1	-0.7	-0.4	-0.9	-1.0	-0.1	-0.6	0.3	0.0	-0.8	-0.6	-0.6	-0.8	-0.3	-0.6	-0.6	-0.1	-0.3	-0.5	0.3	-0.7	-0.4	-0.5	-0.2	-0.5	0.3	-1.1
Commuting to job workplace: Cycle	0.3	0.4	0.9	0.6	0.8	0.9	0.8	0.3	-0.3	-0.0	0.1	0.7	0.6	0.8	0.6	0.4	0.5	0.6	0.4	0.4	0.6	0.6	0.9	0.8	0.3	0.2	0.7	0.6	1.0
Heart disease (siblings)	0.3	0.4	1.4	-0.5	-0.1	-0.3	-0.1	-0.7	-0.4	-0.7	-0.7	1.2	-0.5	-0.3	-0.5	-0.6	-0.6	-0.5	-0.6	-0.9	-1.1	-0.6	-0.3	-0.1	0.3	-0.7	-0.3	-0.6	0.8
Major Depression (MDD)	0.2	0.2	1.0	0.1	-0.0	-0.1	-0.3	0.5	-0.1	0.7	0.9	-0.3	0.2	0.2	0.1	0.4	0.2	0.2	0.6	0.2	0.3	0.7	-0.5	0.3	0.0	0.5	0.2	1.0	-0.9
Reaction Time	0.2	0.4	1.8	0.2	-0.0	-0.1	-0.3	0.9	-0.3	1.3	0.8	-0.5	0.3	0.6	0.1	0.8	0.5	0.4	0.9	0.4	0.2	1.1	0.1	0.4	-0.0	0.4	0.4	1.3	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.2	-0.0	0.6	0.5	0.6	-0.8	-0.0	-1.1	-0.8	0.5	-0.1	-0.1	0.0	-0.7	-0.3	-0.2	-0.7	-0.8	0.9	-0.7	0.9	0.1	-0.7	-0.8	-0.1	-0.7	0.6
Body Mass Index (BMI) (2010)	0.2	0.2	1.0	0.2	-0.0	0.1	-0.0	0.5	0.5	1.0	0.6	-0.6	0.3	0.3	0.2	0.5	0.4	0.3	0.5	0.5	-0.4	0.3	-0.2	-0.0	0.7	1.0	0.2	0.6	-0.8
Mean Putamen Volume	0.2	0.2	2.4	0.3	0.1	0.4	0.3	0.1	0.7	-0.2	-0.3	0.1	0.2	0.2	0.0	0.2	0.3	0.2	0.2	0.1	1.5	0.7	0.3	0.6	-0.5	0.6	0.3	0.4	0.8
Primary Biliary Cirrhosis	0.2	0.3	1.3	-0.3	-0.5	-0.0	-0.1	-0.7	-0.8	-1.1	-0.7	-0.1	-0.4	-0.2	-0.4	-0.6	-0.5	-0.4	-0.7	-0.7	0.3	-0.7	-0.6	-0.5	-0.7	-0.1	-0.5	-0.6	0.3
Ulcerative Colitis	0.2	0.2	1.1	0.1	-0.1	-0.2	-0.3	0.6	-0.2	1.1	0.6	-0.4	0.2	-0.3	0.2	0.6	0.1	0.2	0.5	0.0	-0.9	0.1	-0.5	-0.3	0.6	0.8	0.1	0.4	-0.6
Blood Eosinophil Count	0.2	1.8	4.2	1.5	1.4	1.4	1.2	1.5	0.7	1.4	2.0	1.4	1.5	1.5	1.5	1.5	1.5	1.5	1.6	1.3	0.0	1.3	1.2	1.2	1.4	0.9	1.4	1.4	-0.3
Diabetes (father)	0.2	0.3	1.7	-0.5	-0.2	-0.4	-0.4	-0.5	-0.3	-0.4	-0.4	-0.0	-0.5	-0.8	-0.5	-0.5	-0.5	-0.5	-0.4	-0.2	0.4	0.1	0.4	-0.1	-0.8	-1.3	-0.4	-0.6	-0.6
Taking other prescription medications	0.2	0.3	0.9	0.4	0.5	0.2	0.2	0.6	0.4	0.6	0.8	0.9	0.4	0.7	0.4	0.5	0.5	0.4	0.6	0.7	-0.3	0.9	0.9	0.6	0.2	-0.7	0.5	0.3	-0.3
Had menopause	0.2	0.2	0.6	0.2	-0.1	-0.1	-0.3	0.7	0.3	0.8	0.8	-0.1	0.3	-0.0	0.3	0.6	0.4	0.3	0.6	0.7	-0.6	0.3	-0.4	-0.3	0.3	0.2	0.1	0.2	-0.7
Qualifications: None of the above	0.2	0.5	2.3	-0.1	-0.5	-0.6	-0.9	0.9	0.1	1.3	1.2	-0.5	0.0	0.6	-0.0	0.8	0.3	0.1	0.9	0.8	-0.6	1.3	-0.3	-0.0	0.2	0.1	0.1	1.0	-1.5
Alcohol intake versus 10 years previously	0.2	0.3	2.6	-0.4	-0.4	-0.7	-0.8	0.3	-0.3	0.3	0.2	0.2	-0.3	0.0	-0.3	0.1	-0.1	-0.2	0.2	0.2	-1.6	0.4	-1.1	-0.3	-0.7	-0.5	-0.3	0.3	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.9	0.4	0.1	0.0	-0.0	0.8	0.3	0.7	0.9	0.1	0.4	0.2	0.4	0.7	0.5	0.5	0.7	0.8	-1.4	0.1	-0.3	-0.2	0.2	0.3	0.2	0.0	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	1.1	0.1	0.1	0.0	-0.2	0.4	0.5	0.9	0.5	-0.7	0.2	0.4	0.1	0.4	0.3	0.2	0.5	0.6	0.2	1.1	0.0	0.2	0.3	0.2	0.1	0.7	-0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	2.3	0.1	0.2	-0.0	-0.3	0.7	0.5	1.0	0.7	-0.2	0.2	0.7	0.2	0.7	0.4	0.3	0.8	0.6	0.4	1.5	-0.1	0.7	0.2	0.2	0.5	1.5	-0.4
Number of full brothers	0.2	0.3	3.6	0.1	-0.3	-0.3	-0.2	0.6	0.5	0.5	0.9	-0.2	0.2	0.3	0.2	0.5	0.3	0.2	0.4	0.7	-1.9	-0.1	-0.8	-0.3	0.2	-0.2	0.1	-0.2	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.6	0.5	0.2	0.4	0.5	0.5	0.4	0.8	0.7	0.5	0.5	0.2	0.4	0.4	0.5	0.5	0.3	0.5	-0.8	-0.6	-0.5	-0.2	1.3	0.0	0.3	-0.6	-0.2
Had major operations	0.2	0.3	1.7	-0.0	-0.1	-0.1	-0.4	0.5	0.1	0.8	0.6	-0.2	0.0	0.3	-0.0	0.4	0.1	0.1	0.5	0.4	0.1	1.3	0.7	0.3	-0.2	-0.3	0.2	0.8	-1.1
Family relationship satisfaction	0.2	0.2	0.9	-0.4	-0.2	-0.6	-0.7	-0.0	-0.0	0.2	-0.2	-0.5	-0.4	-0.7	-0.4	-0.2	-0.2	-0.4	0.0	0.1	0.1	0.6	0.3	-0.0	-0.9	-1.0	-0.3	0.4	-0.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.4	-0.1	-0.2	-0.2	-0.1	-0.0	0.1	0.2	0.3	-0.1	-0.1	-0.2	-0.1	-0.0	-0.0	-0.0	-0.2	0.2	-1.2	-0.8	-0.6	-0.6	0.4	0.4	-0.2	-0.3	-1.1
Osteoporosis (self-reported)	0.2	0.2	0.8	-0.3	-0.2	-0.1	-0.1	-0.6	-0.5	-0.5	-0.5	0.4	-0.4	-0.2	-0.5	-0.5	-0.5	-0.4	-0.5	-0.9	0.5	-0.1	0.6	0.1	-0.0	-0.5	-0.2	-0.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.3	-0.3	0.3	0.2	0.4	-1.0	-0.4	-1.5	-0.9	0.3	-0.4	-0.5	-0.3	-0.9	-0.6	-0.4	-0.9	-1.3	1.1	-0.6	0.5	0.1	-0.9	-0.6	-0.2	-0.4	0.7
Mother’s age at death	0.2	0.2	0.8	-0.4	-0.8	-0.5	-0.6	-0.2	0.2	0.2	-0.5	-0.9	-0.4	-0.2	-0.5	-0.2	-0.3	-0.4	-0.3	-0.1	-0.2	-0.2	-0.8	-0.7	0.1	0.6	-0.6	0.1	-0.5
Eye problems/disorders: Glaucoma	0.2	0.2	1.4	0.4	0.2	0.3	0.4	0.3	0.7	0.4	0.3	0.7	0.3	0.3	0.3	0.4	0.3	0.3	0.2	0.2	0.0	-0.4	0.1	-0.0	1.2	0.7	0.3	-0.1	0.4
High cholesterol (Self-reported)	0.2	0.4	2.6	0.5	0.7	0.9	1.1	-0.3	0.1	-0.8	-0.3	1.1	0.4	0.0	0.5	-0.2	0.3	0.4	-0.3	-0.1	1.6	-0.7	1.0	0.3	0.3	0.1	0.3	-0.5	0.8
Medication: Bendroflumethiazide	0.2	0.3	1.5	0.3	0.8	0.6	0.6	-0.1	0.2	0.0	-0.3	0.6	0.2	0.2	0.3	-0.1	0.1	0.2	-0.1	-0.0	1.0	0.0	0.7	0.5	1.2	0.7	0.4	0.1	0.9
Alcohol drinker status: Never	0.2	0.3	0.9	0.6	0.7	0.6	0.9	0.3	0.4	-0.0	0.2	0.2	0.6	0.0	0.6	0.3	0.5	0.6	0.2	0.4	-0.8	-0.5	0.1	0.4	0.3	0.9	0.6	-0.3	0.6
Ever depressed for a whole week	0.2	0.3	1.5	-0.5	-0.3	-0.4	-0.8	-0.2	-0.2	0.1	-0.3	-0.4	-0.5	-0.6	-0.5	-0.4	-0.4	-0.5	-0.1	-0.2	1.2	0.7	-0.1	-0.1	-0.7	-0.9	-0.4	0.2	-0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.0	0.6	0.4	0.5	0.6	0.5	1.0	0.6	0.6	0.4	0.6	0.7	0.7	0.5	0.6	0.6	0.5	0.8	-0.7	0.1	0.4	0.3	0.8	0.2	0.5	0.1	0.3
Bipolar Disorder (2018)	0.1	0.2	1.1	0.2	0.2	0.5	0.6	-0.3	-0.4	-0.7	-0.7	0.3	0.1	-0.4	0.2	-0.2	-0.0	0.0	-0.4	-0.5	1.0	-0.7	0.4	0.0	-0.6	0.1	0.0	-0.6	0.9
Bipolar Disorder or Schizophrenia	0.1	0.2	0.8	0.4	-0.1	0.1	0.1	0.7	-0.0	0.6	0.9	-0.1	0.4	0.9	0.5	0.7	0.5	0.5	0.6	0.2	-0.6	0.2	-0.5	-0.1	0.3	0.4	0.3	0.5	-0.5
Depressed Affect (Nagel 2018)	0.1	0.1	1.0	-0.0	0.3	-0.3	-0.3	0.4	-0.3	0.6	0.4	-0.1	0.0	-0.1	-0.1	0.3	0.1	0.0	0.5	0.6	-0.3	1.0	-0.0	0.5	-0.5	-0.1	0.3	0.3	-0.4
Alzheimer’s Disease (in father)	0.1	0.1	0.5	0.1	0.3	0.1	-0.0	0.2	0.6	0.1	0.5	0.2	0.1	0.2	0.2	0.2	0.2	0.1	0.3	0.4	0.6	0.7	0.5	0.5	-0.0	-0.4	0.3	0.5	-0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.6	-0.1	-0.3	-0.3	-0.4	0.2	0.4	0.7	0.1	-0.5	-0.1	0.4	-0.0	0.2	0.1	-0.1	0.2	0.3	0.2	0.3	-0.5	-0.3	0.8	0.7	-0.1	0.5	0.0
Breast Cancer	0.1	0.3	1.7	-0.1	0.5	0.2	0.4	-0.6	0.4	-0.2	-0.9	1.2	-0.1	-0.2	-0.1	-0.4	-0.1	-0.2	-0.5	-0.2	0.8	-0.2	1.2	0.3	0.9	0.0	0.0	-0.3	1.3
Blood White Count	0.1	0.7	4.9	-0.1	-0.7	-0.6	-0.7	0.6	0.1	1.1	1.4	-0.4	-0.0	0.4	0.0	0.5	0.2	0.0	0.5	0.6	-2.2	0.2	-1.1	-0.6	0.7	-0.6	-0.2	0.4	-1.9
Heel T-Score	0.1	0.7	5.0	-0.2	-0.1	-0.2	-0.1	-0.4	1.2	-1.2	-1.6	-0.4	-0.3	-0.2	-0.1	-0.3	-0.1	-0.3	-0.6	0.3	-1.1	-0.9	-0.6	-0.6	-2.2	0.4	-0.5	-1.1	1.8
Allergy or Eczema	0.1	0.3	2.8	0.2	0.5	0.3	0.5	-0.2	0.5	-0.5	-0.7	1.2	0.1	-0.1	0.1	-0.1	-0.1	0.1	-0.2	-0.2	0.5	-0.3	0.2	0.2	0.2	0.4	0.2	-0.3	1.7
Cardiovascular Disease	0.1	0.3	1.1	-0.1	0.2	0.1	0.3	-0.6	-0.7	-1.0	-0.5	0.7	-0.1	-0.6	-0.0	-0.5	-0.2	-0.2	-0.6	-0.7	0.1	-1.0	-0.2	-0.3	0.0	-0.4	-0.2	-0.9	0.9
Respiratory disease	0.1	0.2	1.3	-0.0	0.3	-0.0	-0.0	0.1	0.1	0.4	0.1	0.9	0.0	0.2	-0.1	0.1	0.0	0.0	0.3	-0.0	0.4	0.8	1.1	0.7	0.5	-0.2	0.3	0.2	0.7
Tanning	0.1	1.4	5.8	-0.3	-1.2	-1.2	-1.7	1.2	0.7	1.8	1.3	-1.3	-0.2	-0.2	-0.3	1.0	0.3	-0.0	1.0	1.2	-2.4	1.1	-1.7	-1.0	0.3	0.3	-0.4	1.1	-2.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	1.0	0.3	0.2	0.1	0.2	0.4	0.1	0.3	0.3	0.3	0.3	0.3	0.2	0.3	0.3	0.3	0.3	0.6	-0.7	-0.3	0.5	-0.0	1.0	0.4	0.2	-0.5	0.7
Supplements: Zinc	0.1	0.1	1.0	0.0	-0.2	-0.3	-0.3	0.5	0.5	0.3	0.4	-0.2	0.0	-0.0	-0.1	0.4	0.2	0.1	0.3	0.5	-0.5	0.2	-1.0	-0.1	-0.5	0.2	0.1	0.2	-0.4
Average weekly fortified wine intake	0.1	0.1	0.5	-0.2	-0.2	-0.1	-0.1	-0.4	-0.1	-0.5	-0.7	0.0	-0.3	-0.5	-0.2	-0.4	-0.1	-0.3	-0.5	0.1	0.6	-0.6	-0.2	-0.5	-0.3	0.2	-0.4	-0.5	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	1.3	-0.2	-0.3	-0.1	-0.0	-0.4	-0.5	-0.6	-0.2	-0.0	-0.2	-0.3	-0.3	-0.4	-0.1	-0.2	-0.3	-0.3	1.1	-0.2	0.2	-0.1	-0.4	-0.6	-0.3	-0.2	0.4
Chronic bronchitis/emphysema (father)	0.1	0.2	0.4	0.5	0.3	0.3	0.4	0.5	0.4	0.2	0.3	0.3	0.5	0.2	0.5	0.5	0.5	0.5	0.4	0.5	-0.3	-0.0	0.4	0.2	0.6	0.5	0.4	-0.1	0.6
Allergy	0.1	0.2	1.5	0.2	-0.2	0.5	0.6	-0.5	-0.7	-0.7	-0.0	-0.5	0.1	-0.3	0.1	-0.4	0.0	0.1	-0.5	-0.4	-0.1	-1.2	0.1	-0.3	-0.0	-0.4	-0.1	-0.8	-0.3
Hair/balding pattern: Pattern 3	0.1	0.1	1.5	-0.0	0.0	-0.2	0.0	0.0	0.9	0.0	-0.0	0.2	-0.0	-0.0	-0.0	0.1	0.1	-0.0	-0.0	0.5	-1.2	-0.4	-0.1	-0.2	0.1	0.0	-0.0	-0.1	0.2
Happiness	0.1	0.1	0.7	-0.0	-0.2	-0.3	-0.2	0.3	0.1	0.7	0.5	-0.4	0.1	-0.2	-0.1	0.2	0.2	0.1	0.3	0.5	-0.8	0.0	0.0	-0.2	0.3	-0.0	-0.0	-0.2	-0.6
Asthma	0.1	0.2	1.5	0.0	0.3	0.2	0.3	-0.3	0.0	-0.5	-0.4	1.2	-0.0	-0.0	-0.1	-0.3	-0.1	-0.1	-0.3	-0.6	0.7	-0.1	1.0	0.3	0.3	-0.6	0.1	-0.6	0.8
Medication: Lansoprazole	0.1	0.1	0.7	0.2	0.4	0.2	0.2	0.2	0.5	0.2	0.0	0.6	0.2	0.2	0.2	0.2	0.2	0.2	0.3	0.2	0.4	0.4	0.0	0.4	-0.0	0.8	0.3	0.6	0.4
Pulse wave Arterial Stiffness index	0.1	0.1	0.5	-0.1	-0.1	-0.2	-0.2	0.1	0.0	0.3	-0.1	0.4	-0.1	-0.3	-0.3	0.1	-0.1	-0.0	0.2	0.0	0.7	0.3	0.5	0.2	0.1	0.5	0.0	0.3	0.4
Peak expiratory flow (PEF)	0.1	0.1	0.9	-0.2	0.3	0.0	0.1	-0.3	-0.3	-0.6	-0.6	0.1	-0.1	-0.3	-0.1	-0.3	-0.2	-0.2	-0.2	-0.5	-0.0	0.2	0.1	0.4	-0.7	-0.2	0.0	0.2	0.9
Pulse wave reflection index	0.1	0.1	0.9	-0.0	0.0	-0.2	-0.1	0.1	0.4	0.1	-0.3	0.0	0.0	-0.1	-0.2	0.1	0.1	0.0	0.2	0.4	0.2	0.2	0.2	0.1	-0.0	0.9	0.1	0.2	0.7
Loud music exposure frequency	0.1	0.1	0.4	-0.3	0.2	-0.2	-0.1	-0.5	-0.6	-0.1	-0.5	0.1	-0.4	-0.2	-0.3	-0.5	-0.5	-0.4	-0.5	-0.6	0.5	-0.0	0.4	0.1	0.5	-0.4	-0.1	-0.0	-0.0
Medication: Paracetamol	0.1	0.1	0.3	-0.3	-0.2	-0.3	-0.3	-0.3	-0.4	-0.3	-0.1	-0.3	-0.3	-0.1	-0.4	-0.4	-0.3	-0.3	-0.3	-0.4	0.3	-0.1	0.0	-0.1	-0.5	-0.4	-0.2	-0.6	-0.5
Glaucoma (self-reported)	0.1	0.1	1.2	-0.0	-0.4	-0.3	-0.1	0.2	0.3	0.7	0.2	-0.2	-0.0	0.1	-0.1	0.2	0.0	-0.0	-0.0	0.1	-0.8	-0.6	-0.2	-0.5	1.1	0.5	-0.1	-0.3	-0.3
Medication: Amlodipine	0.1	0.1	0.7	-0.2	0.0	-0.1	-0.0	-0.4	-0.5	0.1	0.2	0.1	-0.2	-0.3	-0.1	-0.4	-0.3	-0.3	-0.4	-0.6	-0.4	-0.5	0.3	-0.3	0.9	-0.6	-0.2	-0.3	-0.8
High blood pressure (siblings)	0.1	0.2	1.7	-0.0	0.4	0.2	0.2	-0.2	-0.2	-0.6	-0.3	0.7	-0.1	-0.3	-0.1	-0.2	-0.1	-0.1	-0.2	-0.1	1.3	0.2	1.0	0.4	0.0	-0.1	0.1	0.1	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.8	-0.1	-0.4	-0.1	0.0	-0.3	0.0	-0.4	-0.8	-0.3	-0.2	-0.4	-0.1	-0.3	-0.2	-0.2	-0.4	-0.3	0.2	-0.8	-0.2	-0.5	-0.2	0.4	-0.3	-0.7	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.5	-0.0	-0.1	-0.2	-0.1	0.3	-0.1	0.5	0.6	0.0	0.1	0.0	0.0	0.2	0.0	0.1	0.3	0.2	-0.7	0.1	-0.2	0.1	0.3	0.0	0.2	-0.1	-0.6
Illnesses of siblings: Diabetes	0.1	0.2	1.5	0.1	-0.1	-0.1	-0.2	0.5	-0.0	0.7	0.7	-0.4	0.1	0.5	0.1	0.4	0.2	0.2	0.5	0.7	-0.1	0.5	0.4	0.1	-0.1	0.1	0.1	0.4	-1.2
Friendships satisfaction	0.1	0.1	0.3	-0.4	0.1	-0.4	-0.3	-0.5	-0.4	-0.1	-0.5	-0.0	-0.4	-0.6	-0.4	-0.5	-0.4	-0.4	-0.4	-0.5	0.2	-0.1	0.4	0.0	-0.1	0.0	-0.3	-0.1	-0.2
Commuting to job workplace: Walk	0.1	0.1	0.5	0.1	0.3	0.2	0.3	-0.1	0.2	-0.0	0.2	-0.5	0.1	-0.5	0.1	-0.0	0.0	0.0	-0.1	-0.2	0.7	-0.4	0.3	0.1	0.7	-0.6	0.2	-0.4	-0.2
Mineral and other dietary supplements	0.1	0.2	0.7	0.0	-0.1	-0.1	-0.2	0.3	-0.4	0.6	0.5	0.0	0.1	0.3	-0.0	0.3	0.1	0.1	0.4	0.1	-0.2	0.7	-0.6	0.3	0.7	0.6	0.2	0.8	-0.3
Asthma (self-reported)	0.1	0.2	1.1	-0.1	0.2	0.1	0.1	-0.4	-0.1	-0.5	-0.4	1.1	-0.2	-0.1	-0.3	-0.4	-0.2	-0.2	-0.3	-0.7	0.6	-0.1	0.8	0.2	0.2	-0.7	-0.0	-0.6	0.6
Guilty feelings	0.1	0.2	1.5	-0.2	-0.0	-0.2	-0.2	-0.2	-0.2	-0.2	-0.6	-0.9	-0.2	-0.6	-0.1	-0.2	-0.2	-0.2	-0.1	-0.3	0.9	0.2	-0.1	0.1	-1.2	0.1	-0.1	0.1	0.1
Irritability	0.1	0.2	1.9	0.0	0.3	0.3	0.4	-0.4	-0.3	-0.5	-1.0	0.4	0.0	-0.3	-0.1	-0.4	-0.1	-0.0	-0.4	-0.4	0.3	-0.4	0.3	0.2	0.0	0.9	0.0	-0.3	1.4
Alcohol drinker status: Previous	0.1	0.2	1.0	0.3	0.4	0.5	0.6	-0.1	0.3	0.2	-0.2	0.4	0.3	0.2	0.4	-0.0	0.2	0.2	-0.1	-0.1	0.4	-0.5	0.8	-0.0	1.0	0.2	0.2	-0.5	0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.5	2.3	0.8	0.9	1.4	1.3	-0.2	-1.5	-0.6	0.3	1.2	0.6	0.4	0.7	-0.1	0.2	0.6	-0.1	0.1	1.1	-0.0	0.8	0.6	-0.2	-0.2	0.5	-0.3	-0.5
Waist Hip Ratio (WHR)	0.0	0.2	1.0	-0.3	-0.5	-0.3	-0.2	-0.3	-0.4	-0.5	-0.1	-1.0	-0.3	-0.2	-0.3	-0.3	-0.3	-0.3	-0.4	-0.4	-0.0	-0.8	-0.7	-0.6	-0.1	0.1	-0.4	-0.8	-0.3
Hair Pigment	0.0	1.0	6.9	0.6	0.9	1.1	1.2	-0.2	1.1	-0.9	-0.6	1.6	0.5	0.4	0.6	-0.1	0.2	0.5	0.0	0.5	1.6	0.4	0.4	1.2	0.5	1.8	0.8	0.2	2.6
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.3	-0.1	0.1	-0.3	-0.2	0.1	0.4	0.2	-0.3	0.4	-0.1	-0.1	-0.1	0.1	-0.2	-0.1	0.1	0.1	-0.3	0.3	-0.3	0.1	-0.0	0.5	0.0	0.2	0.6
Medication: Paracetamol	0.0	0.1	0.5	-0.1	-0.1	-0.3	-0.3	0.2	-0.0	0.4	0.4	-0.5	-0.0	0.2	-0.1	0.1	0.1	-0.0	0.2	0.1	-0.1	0.2	0.1	-0.1	-0.2	-0.0	-0.0	-0.1	-0.7