Best TWAS P=1.19e-12 · Best GWAS P=1.55e-15 conditioned to 5.13e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 7.0 | -7.1 | 1.2e-12 | -0.85 | 0.16 | 0.82 | TRUE |
2 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 6.8 | -6.7 | 2.6e-11 | 0.03 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TAL1 | 0.03 | 0.02 | blup | 75 | 0.02 | 9.2e-03 | 5.9 | 5.5 | 4.4e-08 | -0.01 | 0.02 | 0.81 | FALSE |