TWAS
hub
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Usage
Models
Genes
Traits
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Traits
:
Body mass index (BMI)
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chr1:46,982,455-51,180,660
Best TWAS P=1.19e-12 · Best GWAS P=1.55e-15 conditioned to 5.13e-05
47M
47.5M
48M
48.5M
49M
49.5M
50M
50.5M
51M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
METSIM
Adipose
AGBL4
0.02
0.02
lasso
5
0.02
1.3e-03
7.0
-7.1
1.2e-12
-0.85
0.16
0.82
TRUE
2
YFS
Blood
TAL1
0.03
0.02
bslmm
402
0.02
2.6e-06
6.8
-6.7
2.6e-11
0.03
0.01
0.99
TRUE
3
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
TAL1
0.03
0.02
blup
75
0.02
9.2e-03
5.9
5.5
4.4e-08
-0.01
0.02
0.81
FALSE