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chr9:13,891,813-16,758,776

Best TWAS P=8.21e-21 · Best GWAS P=1.61e-18 conditioned to 0.000163

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	CCDC171	0.10	0.09	enet	9	0.12	7.2e-10	4.3	-6.0	1.9e-09	0.38	0.74	0.26	FALSE
2	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	8.0	-8.5	2.9e-17	0.71	0.12	0.87	FALSE
3	GTEx	Brain Caudate basal ganglia	RP11-408A13.4	0.30	0.17	lasso	9	0.16	2.5e-05	4.9	5.4	5.1e-08	0.07	0.17	0.28	TRUE
4	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-8.2	-9.4	8.2e-21	0.69	0.20	0.77	TRUE
5	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-8.4	-8.7	3.5e-18	0.73	0.07	0.92	FALSE
6	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-6.3	-7.6	2.7e-14	0.66	0.16	0.75	FALSE
7	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	8.0	-7.9	2.0e-15	0.62	0.10	0.82	FALSE
8	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-8.2	-7.2	7.0e-13	0.66	0.11	0.61	FALSE
9	GTEx	Breast Mammary Tissue	CCDC171	0.21	0.01	lasso	5	0.03	1.5e-02	7.3	-5.4	6.3e-08	0.48	0.29	0.37	FALSE
10	GTEx	Lung	CCDC171	0.13	0.03	enet	9	0.01	5.0e-02	4.6	-6.5	7.5e-11	0.49	0.40	0.37	FALSE
11	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-8.3	-8.3	1.6e-16	0.73	0.17	0.83	FALSE
12	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	7.4	7.1	9.0e-13	-0.62	0.14	0.58	FALSE
13	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	7.7	-8.1	5.1e-16	0.68	0.23	0.69	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CCDC171	0.20	0.04	enet	45	0.06	4.9e-04	7.9	-5.2	2.2e-07	0.23	0.60	0.30	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CCDC171	0.14	0.09	enet	13	0.12	1.9e-10	7.4	-6.2	4.4e-10	0.43	0.86	0.14	FALSE
16	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	8.0	-7.2	8.1e-13	0.59	0.23	0.52	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	8.1	-7.9	2.1e-15	0.64	0.60	0.40	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf93	0.06	0.05	lasso	3	0.03	5.3e-03	7.4	-6.6	5.0e-11	0.61	0.12	0.32	FALSE