[Hub]/) : Traits : Body mass index (BMI) :

chr10:64,195,778-65,606,229

Best TWAS P=2.1e-09 · Best GWAS P=1.57e-10 conditioned to 0.00318

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cortex NRBF2 0.30 0.26 enet 24 0.21 1.4e-06 4.9 5.5 3.1e-08 -0.52 0.30 0.68 FALSE
2 GTEx Brain Frontal Cortex BA9 NRBF2 0.25 0.17 lasso 6 0.16 6.1e-05 -5.4 5.8 7.7e-09 -0.54 0.22 0.62 FALSE
3 GTEx Stomach NRBF2 0.09 0.04 lasso 6 0.03 1.6e-02 3.4 5.1 2.9e-07 -0.46 0.05 0.59 FALSE
4 GTEx Testis NRBF2 0.14 0.08 lasso 12 0.09 6.7e-05 -5.3 5.6 2.5e-08 -0.52 0.48 0.40 FALSE
5 NTR Blood NRBF2 0.03 0.01 bslmm 386 0.01 3.4e-05 -2.5 -5.2 2.3e-07 0.30 0.19 0.08 FALSE
6 ROSMAP Brain Pre-frontal Cortex NRBF2 0.34 0.46 lasso 5 0.46 3.1e-66 -5.4 5.7 1.2e-08 -0.55 0.49 0.51 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma NRBF2 0.05 0.06 lasso 2 0.06 5.5e-12 -5.4 5.5 4.7e-08 -0.55 0.26 0.74 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NRBF2 0.04 0.04 enet 5 0.03 1.3e-04 -5.4 5.6 1.9e-08 -0.51 0.16 0.42 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NRBF2 0.10 0.06 lasso 7 0.08 3.5e-09 4.7 5.5 2.9e-08 -0.44 0.63 0.37 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma NRBF2 0.08 0.08 enet 6 0.08 4.3e-09 -5.4 5.6 2.0e-08 -0.57 0.26 0.74 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NRBF2 0.09 0.02 enet 6 0.04 1.4e-05 2.9 5.2 2.1e-07 -0.51 0.39 0.38 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma NRBF2 0.18 0.13 enet 11 0.08 2.5e-04 -5.4 6.0 2.1e-09 -0.73 0.03 0.90 TRUE
13 The Cancer Genome Atlas Prostate Adenocarcinoma NRBF2 0.08 0.09 lasso 6 0.08 9.7e-09 -5.4 5.6 2.8e-08 -0.52 0.26 0.74 FALSE