Best TWAS P=2.98e-19 · Best GWAS P=1.03e-20 conditioned to 0.0448
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100499489 | 0.06 | 0.00 | bslmm | 297 | 0.02 | 1.2e-03 | 1.1 | -5.3 | 9.8e-08 | -0.49 | 0.02 | 0.76 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | NEBL | 0.07 | 0.01 | blup | 662 | 0.03 | 9.7e-05 | -4.4 | -6.4 | 1.7e-10 | -0.03 | 0.76 | 0.01 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.0e-04 | 8.5 | -9.0 | 3.0e-19 | -0.94 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 6.1e-02 | 7.4 | 8.1 | 7.3e-16 | 0.90 | 0.08 | 0.83 | FALSE |
| 5 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 1.0e-01 | 7.4 | -8.3 | 1.4e-16 | -0.92 | 0.02 | 0.67 | FALSE |