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Body mass index (BMI)
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chr10:20,372,032-23,424,277
Best TWAS P=2.98e-19 · Best GWAS P=1.03e-20 conditioned to 0.0448
20.5M
21M
21.5M
22M
22.5M
23M
23.5M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Skin Sun Exposed Lower leg
MLLT10
0.06
0.02
lasso
4
0.03
8.0e-04
8.5
-9.0
3.0e-19
-0.94
0.01
0.99
TRUE
2
CommonMind
Brain Pre-frontal Cortex
NEBL
0.07
0.01
blup
662
0.03
9.7e-05
-4.4
-6.4
1.7e-10
-0.03
0.76
0.01
TRUE
5
GTEx
Spleen
MLLT10
0.16
0.02
lasso
7
0.02
1.0e-01
7.4
-8.3
1.4e-16
-0.92
0.02
0.67
FALSE
4
GTEx
Skin Sun Exposed Lower leg
CASC10
0.08
0.02
lasso
5
0.01
6.1e-02
7.4
8.1
7.3e-16
0.90
0.08
0.83
FALSE
1
CommonMind
Brain Pre-frontal Cortex
LOC100499489
0.06
0.00
bslmm
297
0.02
1.2e-03
1.1
-5.3
9.8e-08
-0.49
0.02
0.76
FALSE