Best TWAS P=2.22e-12 · Best GWAS P=9.62e-25 conditioned to 6.97e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-446E9.1 | 0.07 | 0.00 | lasso | 6 | 0.00 | 6.6e-01 | -4.8 | 5.6 | 2.8e-08 | -0.71 | 0.04 | 0.48 | FALSE |
| 2 | GTEx | Brain Cerebellum | RPS20 | 0.26 | 0.07 | enet | 17 | 0.10 | 5.4e-04 | -6.1 | -5.5 | 3.4e-08 | 0.64 | 0.10 | 0.75 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RPS20 | 0.12 | 0.04 | lasso | 6 | 0.05 | 7.2e-04 | -6.2 | -6.0 | 2.3e-09 | 0.81 | 0.19 | 0.70 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | RPS20 | 0.18 | 0.03 | enet | 12 | 0.07 | 1.5e-04 | -5.9 | -7.0 | 2.2e-12 | 0.80 | 0.19 | 0.34 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RPS20 | 0.33 | 0.07 | enet | 8 | 0.07 | 1.7e-08 | -4.4 | -5.1 | 2.9e-07 | 0.52 | 0.24 | 0.72 | FALSE |