[Hub]/) : Traits : Weight : ← →

chr10:125,739,009-127,174,440

Best TWAS P=2.71e-09 · Best GWAS P=6.92e-10 conditioned to 9.3e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex METTL10 0.20 0.26 lasso 9 0.26 4.5e-31 -5.1 -5.2 1.8e-07 -0.04 0.36 0.64 FALSE
2 GTEx Brain Caudate basal ganglia METTL10 0.33 0.16 lasso 3 0.18 7.6e-06 4.0 -5.1 2.9e-07 -0.03 0.38 0.33 FALSE
3 GTEx Lung METTL10 0.11 0.06 enet 6 0.05 1.7e-04 -5.1 -5.3 1.0e-07 -0.02 0.50 0.46 FALSE
4 GTEx Thyroid METTL10 0.19 0.09 enet 33 0.10 3.0e-08 -5.1 -5.2 2.1e-07 -0.02 0.43 0.57 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma METTL10 0.09 0.08 blup 43 0.11 1.2e-09 -5.2 -5.2 1.7e-07 -0.02 0.01 0.98 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma METTL10 0.06 0.13 lasso 7 0.13 1.1e-25 -5.2 -5.3 1.5e-07 -0.04 0.01 0.99 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma METTL10 0.10 0.14 blup 43 0.14 7.4e-16 -5.2 -5.2 2.2e-07 -0.02 0.01 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma METTL10 0.10 0.16 lasso 7 0.17 1.0e-18 -5.2 -5.2 1.9e-07 -0.04 0.01 0.99 FALSE
9 The Cancer Genome Atlas Liver Hepatocellular Carcinoma METTL10 0.11 0.08 blup 43 0.12 4.8e-06 -5.0 -5.5 3.8e-08 -0.04 0.01 0.98 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma METTL10 0.11 0.19 lasso 6 0.19 7.3e-22 -5.1 -5.2 2.2e-07 -0.03 0.01 0.99 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma METTL10 0.10 0.17 blup 43 0.18 1.9e-18 -5.2 -5.3 1.2e-07 -0.04 0.01 0.99 FALSE
12 The Cancer Genome Atlas Rectum Adenocarcinoma METTL10 0.25 0.11 lasso 4 0.23 3.8e-06 -5.2 -5.9 2.7e-09 0.01 0.02 0.90 TRUE