[Hub]/) : Traits : Weight : ← →

chr10:123,438,113-124,889,817

Best TWAS P=1.58e-12 · Best GWAS P=5.53e-11 conditioned to 0.361

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 6.5 -6.6 4.3e-11 -0.99 0.01 0.99 FALSE
2 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -6.0 -5.2 2.2e-07 -0.67 0.11 0.85 FALSE
3 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 6.5 -6.2 4.2e-10 -0.97 0.01 0.99 FALSE
4 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -5.5 -5.8 7.9e-09 -0.61 0.21 0.55 FALSE
5 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 6.5 -7.1 1.6e-12 -0.86 0.01 0.99 TRUE
6 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -6.0 -6.0 2.5e-09 -0.77 0.15 0.85 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 6.5 -6.5 9.2e-11 -0.99 0.01 0.99 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 6.5 -5.7 1.2e-08 -0.93 0.01 0.88 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -6.0 -5.7 1.5e-08 -0.74 0.01 0.98 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 6.5 -6.5 9.1e-11 -0.99 0.01 0.99 FALSE