Best TWAS P=5.99e-08 · Best GWAS P=1.07e-07 conditioned to 0.00703
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | POLR2L | 0.16 | 0.03 | enet | 10 | 0.03 | 1.9e-02 | -5.3 | -5.2 | 2.2e-07 | 0.85 | 0.01 | 0.98 | FALSE |
| 2 | METSIM | Adipose | POLR2L | 0.03 | 0.02 | bslmm | 413 | 0.01 | 5.0e-03 | -3.2 | -5.4 | 6.0e-08 | 0.57 | 0.18 | 0.08 | TRUE |
| 3 | YFS | Blood | POLR2L | 0.26 | 0.19 | bslmm | 383 | 0.30 | 2.4e-98 | -3.6 | 5.2 | 2.2e-07 | -0.78 | 0.28 | 0.30 | FALSE |