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chr10:133,309,117-135,192,153

Best TWAS P=1.74e-09 · Best GWAS P=5.2e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Pituitary DPYSL4 0.24 0.11 lasso 4 0.26 3.0e-07 3.1 5.5 5.0e-08 0.63 0.02 0.82 FALSE
2 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DPYSL4 0.31 0.19 lasso 10 0.18 3.4e-09 6.1 5.9 3.2e-09 0.91 0.00 1.00 FALSE
3 The Cancer Genome Atlas Glioblastoma Multiforme STK32C 0.13 -0.01 blup 107 0.08 1.6e-03 2.5 -5.2 2.2e-07 -0.35 0.04 0.07 FALSE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPYSL4 0.16 0.21 enet 16 0.24 7.1e-27 6.1 5.2 2.3e-07 0.91 0.00 1.00 FALSE
5 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DPYSL4 0.17 0.24 lasso 3 0.23 2.4e-13 6.2 6.0 1.7e-09 0.98 0.00 1.00 TRUE
6 The Cancer Genome Atlas Brain Lower Grade Glioma DPYSL4 0.13 0.12 lasso 7 0.16 3.1e-17 6.2 5.4 7.9e-08 0.93 0.00 1.00 FALSE
7 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DPYSL4 0.13 0.11 enet 7 0.08 2.0e-04 6.1 6.0 2.1e-09 0.96 0.01 0.98 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma DPYSL4 0.17 0.16 enet 18 0.23 1.5e-26 6.2 5.2 1.8e-07 0.86 0.00 1.00 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma GPR123 0.05 0.00 blup 56 0.02 8.0e-04 3.3 5.4 7.9e-08 0.00 0.00 0.05 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma DPYSL4 0.34 0.37 enet 15 0.46 2.2e-53 -5.3 5.2 2.1e-07 0.92 0.01 0.99 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors DPYSL4 0.17 0.12 blup 64 0.11 1.3e-04 -5.4 5.1 2.8e-07 0.85 0.01 0.97 FALSE