Best TWAS P=8.6e-10 · Best GWAS P=9.9e-10 conditioned to 0.0447
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | RRAS2 | 0.18 | 0.13 | enet | 19 | 0.15 | 2.7e-07 | -4.5 | 5.5 | 3.5e-08 | 0.21 | 0.05 | 0.94 | FALSE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RRAS2 | 0.13 | 0.01 | blup | 11 | 0.05 | 4.0e-03 | 6.1 | 6.1 | 8.6e-10 | 0.80 | 0.00 | 0.93 | TRUE |