Best TWAS P=1.17e-08 · Best GWAS P=6.14e-09 conditioned to 0.0027
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | SP1 | 0.12 | 0.13 | lasso | 5 | 0.08 | 9.5e-05 | 4.7 | 5.2 | 1.6e-07 | -0.23 | 0.41 | 0.55 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | PRR13 | 0.22 | 0.16 | lasso | 4 | 0.18 | 3.2e-07 | 4.4 | -5.3 | 9.3e-08 | 0.29 | 0.25 | 0.15 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PRR13 | 0.13 | 0.04 | blup | 28 | 0.07 | 3.3e-06 | 4.2 | -5.6 | 2.1e-08 | 0.58 | 0.07 | 0.40 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PRR13 | 0.07 | 0.04 | blup | 28 | 0.05 | 4.7e-06 | 4.4 | -5.7 | 1.2e-08 | 0.60 | 0.32 | 0.34 | TRUE |