Best TWAS P=6.64e-13 · Best GWAS P=3.94e-24 conditioned to 1.13e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TRIM13 | 0.15 | 0.04 | lasso | 5 | 0.12 | 1.1e-14 | 5.4 | -5.4 | 7.6e-08 | 0.22 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Artery Aorta | EBPL | 0.43 | 0.20 | enet | 78 | 0.28 | 8.1e-16 | 4.9 | -5.2 | 2.0e-07 | 0.14 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Nerve Tibial | DLEU2 | 0.11 | 0.05 | lasso | 3 | 0.02 | 7.8e-03 | 5.7 | 5.7 | 1.1e-08 | -0.11 | 0.51 | 0.02 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | EBPL | 0.28 | 0.21 | lasso | 5 | 0.20 | 2.5e-16 | 5.1 | -5.3 | 1.1e-07 | 0.02 | 1.00 | 0.00 | FALSE |
| 5 | GTEx | Testis | EBPL | 0.33 | 0.17 | lasso | 6 | 0.24 | 8.4e-11 | 4.8 | -5.6 | 2.4e-08 | 0.03 | 1.00 | 0.00 | TRUE |
| 6 | NTR | Blood | DLEU7 | 0.07 | 0.02 | enet | 22 | 0.06 | 1.3e-19 | -4.1 | -7.2 | 6.6e-13 | 0.61 | 0.11 | 0.89 | TRUE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | DLEU2 | 0.03 | 0.01 | blup | 61 | 0.02 | 2.4e-03 | 5.6 | 6.6 | 4.7e-11 | -0.10 | 0.01 | 0.96 | TRUE |