Best TWAS P=4.12e-12 · Best GWAS P=1.54e-23 conditioned to 8.75e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | C14orf39 | 0.06 | 0.05 | lasso | 3 | 0.05 | 2.7e-05 | 4.5 | -6.9 | 4.1e-12 | -0.59 | 0.25 | 0.72 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | PCNXL4 | 0.15 | 0.05 | enet | 15 | 0.12 | 6.2e-07 | 2.0 | -6.8 | 9.6e-12 | -0.59 | 0.72 | 0.14 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 4.4 | -6.7 | 2.7e-11 | -0.54 | 0.08 | 0.31 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 4.8 | -6.4 | 1.9e-10 | -0.52 | 0.07 | 0.49 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 4.9 | -6.2 | 6.2e-10 | -0.50 | 1.00 | 0.00 | FALSE |