Best TWAS P=1.77e-09 · Best GWAS P=3.5e-06 conditioned to 0.382
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | DCAF4 | 0.23 | 0.07 | enet | 30 | 0.13 | 4.3e-07 | 4.3 | 5.5 | 4.5e-08 | 0.77 | 0.02 | 0.93 | FALSE |
| 2 | GTEx | Colon Sigmoid | DCAF4 | 0.30 | 0.10 | lasso | 9 | 0.11 | 1.3e-04 | 4.6 | 5.4 | 7.1e-08 | 0.89 | 0.01 | 0.75 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | DCAF4 | 0.18 | 0.01 | enet | 10 | 0.06 | 3.0e-03 | 4.6 | 6.0 | 1.8e-09 | 0.85 | 0.01 | 0.63 | TRUE |
| 4 | GTEx | Esophagus Mucosa | ZFYVE1 | 0.10 | 0.00 | lasso | 7 | 0.00 | 2.0e-01 | 4.6 | 5.8 | 5.1e-09 | 0.80 | 0.03 | 0.68 | FALSE |
| 5 | GTEx | Spleen | DCAF4 | 0.47 | 0.12 | enet | 10 | 0.19 | 1.5e-05 | 4.2 | 5.4 | 6.0e-08 | 0.75 | 0.03 | 0.84 | FALSE |