Best TWAS P=1.7e-09 · Best GWAS P=6.29e-10 conditioned to 0.0259
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | FAM108C1 | 0.02 | 0.01 | bslmm | 542 | 0.01 | 6.1e-03 | -2.6 | 5.2 | 2.5e-07 | 0.54 | 0.06 | 0.52 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 5.7 | -5.4 | 6.1e-08 | -0.86 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -5.2 | -6.0 | 1.7e-09 | -0.81 | 0.03 | 0.66 | TRUE |