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chr17:15,149,905-16,895,160

Best TWAS P=1.1e-08 · Best GWAS P=1.16e-07 conditioned to 0.589

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADORA2B	0.06	0.07	blup	304	0.07	5.0e-09	-5.0	-5.5	3.3e-08	0.92	0.06	0.93	FALSE
2	GTEx	Artery Aorta	TTC19	0.06	0.00	lasso	3	0.00	7.1e-01	-5.2	5.6	2.7e-08	-0.87	0.06	0.44	FALSE
3	GTEx	Artery Coronary	TTC19	0.19	0.07	enet	2	0.03	3.9e-02	-5.2	5.2	1.6e-07	-0.93	0.06	0.71	FALSE
4	GTEx	Brain Cerebellum	ZSWIM7	0.25	0.13	lasso	4	0.12	2.6e-04	-5.0	5.2	2.2e-07	-0.99	0.06	0.93	FALSE
5	GTEx	Pancreas	TTC19	0.12	0.09	enet	9	0.07	8.5e-04	-4.8	5.2	2.6e-07	-0.86	0.08	0.79	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	ADORA2B	0.15	0.13	lasso	3	0.12	3.8e-07	-5.3	-5.3	1.3e-07	0.99	0.04	0.95	FALSE
7	GTEx	Skin Sun Exposed Lower leg	TTC19	0.08	0.18	lasso	3	0.17	6.9e-14	-5.2	5.2	2.2e-07	-0.94	0.05	0.95	FALSE
8	GTEx	Skin Sun Exposed Lower leg	ADORA2B	0.12	0.17	lasso	4	0.17	3.1e-14	-5.2	-5.2	2.4e-07	0.99	0.04	0.95	FALSE
9	GTEx	Spleen	ADORA2B	0.23	0.27	enet	10	0.24	7.4e-07	-5.3	-5.5	5.0e-08	0.97	0.05	0.94	FALSE
10	GTEx	Whole Blood	ADORA2B	0.08	0.00	lasso	5	0.00	2.5e-01	-4.7	-5.5	3.2e-08	0.85	0.05	0.60	FALSE
11	YFS	Blood	PIGL	0.02	0.02	blup	279	0.02	1.5e-06	-3.8	-5.7	1.1e-08	0.88	0.24	0.76	TRUE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ADORA2B	0.13	0.17	blup	37	0.16	8.2e-08	-5.0	-5.2	1.7e-07	0.96	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	ZSWIM7	0.05	0.05	blup	48	0.05	3.3e-06	-4.4	-5.1	3.1e-07	0.98	0.03	0.97	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TTC19	0.03	0.03	enet	8	0.03	2.0e-04	-5.1	5.2	2.0e-07	-0.97	0.04	0.95	FALSE
15	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADORA2B	0.10	0.07	enet	9	0.08	5.0e-06	-5.2	-5.1	3.1e-07	0.94	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	TTC19	0.16	0.21	lasso	5	0.20	1.4e-19	-5.2	5.2	2.6e-07	-0.92	0.03	0.97	FALSE