Best TWAS P=8.99e-12 · Best GWAS P=1.13e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | USP36 | 0.14 | 0.13 | lasso | 3 | 0.13 | 1.7e-15 | 6.1 | -6.2 | 4.6e-10 | -0.94 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | USP36 | 0.50 | 0.16 | enet | 20 | 0.07 | 5.7e-03 | 6.0 | -6.0 | 2.5e-09 | -0.81 | 0.04 | 0.91 | FALSE |
| 3 | GTEx | Brain Cerebellum | USP36 | 0.31 | 0.20 | enet | 18 | 0.13 | 9.7e-05 | 6.0 | -5.4 | 7.7e-08 | -0.77 | 0.06 | 0.82 | FALSE |
| 4 | GTEx | Brain Nucleus accumbens basal ganglia | USP36 | 0.36 | 0.23 | lasso | 5 | 0.20 | 4.8e-06 | 6.8 | -6.8 | 9.0e-12 | -0.99 | 0.01 | 0.99 | TRUE |
| 5 | GTEx | Esophagus Mucosa | USP36 | 0.11 | 0.04 | enet | 13 | 0.06 | 1.1e-04 | 6.3 | -5.4 | 5.7e-08 | -0.86 | 0.03 | 0.96 | FALSE |
| 6 | GTEx | Esophagus Muscularis | USP36 | 0.18 | 0.16 | lasso | 3 | 0.08 | 2.5e-05 | 6.1 | 5.8 | 6.2e-09 | 0.85 | 0.05 | 0.95 | FALSE |
| 7 | GTEx | Muscle Skeletal | CYTH1 | 0.13 | 0.12 | lasso | 3 | 0.13 | 2.5e-12 | 5.8 | 5.7 | 1.2e-08 | 0.90 | 0.24 | 0.76 | FALSE |
| 8 | GTEx | Testis | USP36 | 0.32 | 0.24 | lasso | 6 | 0.26 | 6.2e-12 | 4.6 | -5.7 | 1.1e-08 | -0.91 | 0.10 | 0.90 | FALSE |
| 9 | GTEx | Thyroid | USP36 | 0.21 | 0.15 | enet | 45 | 0.16 | 1.6e-12 | 5.6 | -5.3 | 1.1e-07 | -0.84 | 0.36 | 0.64 | FALSE |