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chr17:75,977,988-77,462,467

Best TWAS P=8.99e-12 · Best GWAS P=1.13e-11 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Nucleus accumbens basal ganglia	USP36	0.36	0.23	lasso	5	0.20	4.8e-06	6.8	-6.8	9.0e-12	-0.99	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	USP36	0.14	0.13	lasso	3	0.13	1.7e-15	6.1	-6.2	4.6e-10	-0.94	0.03	0.97	FALSE
2	GTEx	Brain Cerebellar Hemisphere	USP36	0.50	0.16	enet	20	0.07	5.7e-03	6.0	-6.0	2.5e-09	-0.81	0.04	0.91	FALSE
6	GTEx	Esophagus Muscularis	USP36	0.18	0.16	lasso	3	0.08	2.5e-05	6.1	5.8	6.2e-09	0.85	0.05	0.95	FALSE
8	GTEx	Testis	USP36	0.32	0.24	lasso	6	0.26	6.2e-12	4.6	-5.7	1.1e-08	-0.91	0.10	0.90	FALSE
7	GTEx	Muscle Skeletal	CYTH1	0.13	0.12	lasso	3	0.13	2.5e-12	5.8	5.7	1.2e-08	0.90	0.24	0.76	FALSE
5	GTEx	Esophagus Mucosa	USP36	0.11	0.04	enet	13	0.06	1.1e-04	6.3	-5.4	5.7e-08	-0.86	0.03	0.96	FALSE
3	GTEx	Brain Cerebellum	USP36	0.31	0.20	enet	18	0.13	9.7e-05	6.0	-5.4	7.7e-08	-0.77	0.06	0.82	FALSE
9	GTEx	Thyroid	USP36	0.21	0.15	enet	45	0.16	1.6e-12	5.6	-5.3	1.1e-07	-0.84	0.36	0.64	FALSE