TWAS
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Traits
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chr1:7,392,594-8,878,885
Best TWAS P=4.44e-09 · Best GWAS P=2.07e-08 conditioned to 0.00144
7.4M
7.6M
7.8M
8M
8.2M
8.4M
8.6M
8.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
RP11-431K24.1
0.16
0.16
bslmm
384
0.17
3.1e-21
-5.3
-5.9
4.4e-09
-0.3
0.02
0.98
TRUE
2
The Cancer Genome Atlas
Soft Tissue Sarcoma
VAMP3
0.11
0.07
lasso
4
0.05
7.5e-04
4.9
-5.4
7.6e-08
-0.3
0.00
0.93
TRUE