Best TWAS P=4.44e-09 · Best GWAS P=2.07e-08 conditioned to 0.00144
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | RP11-431K24.1 | 0.16 | 0.16 | bslmm | 384 | 0.17 | 3.1e-21 | -5.3 | -5.9 | 4.4e-09 | -0.3 | 0.02 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Soft Tissue Sarcoma | VAMP3 | 0.11 | 0.07 | lasso | 4 | 0.05 | 7.5e-04 | 4.9 | -5.4 | 7.6e-08 | -0.3 | 0.00 | 0.93 | TRUE |