TWAS
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Genes
Traits
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Traits
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Weight
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chr22:41,181,586-42,907,619
Best TWAS P=4.82e-08 · Best GWAS P=2.27e-09 conditioned to 0.00075
41.2M
41.4M
41.6M
41.8M
42M
42.2M
42.4M
42.6M
42.8M
43M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
ACO2
0.06
0.02
enet
15
0.06
1.2e-05
2.8
5.5
4.8e-08
-0.60
0.56
0.39
TRUE
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
WBP2NL
0.06
0.04
blup
140
0.03
9.6e-05
-4.5
5.2
2.0e-07
-0.64
0.46
0.38
FALSE
1
CommonMind
Brain Pre-frontal Cortex
CCDC134
0.06
0.07
enet
5
0.06
1.2e-07
-4.5
-5.2
2.3e-07
0.90
0.02
0.98
FALSE