Best TWAS P=4.82e-08 · Best GWAS P=2.27e-09 conditioned to 0.00075
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CCDC134 | 0.06 | 0.07 | enet | 5 | 0.06 | 1.2e-07 | -4.5 | -5.2 | 2.3e-07 | 0.90 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Artery Tibial | ACO2 | 0.06 | 0.02 | enet | 15 | 0.06 | 1.2e-05 | 2.8 | 5.5 | 4.8e-08 | -0.60 | 0.56 | 0.39 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | WBP2NL | 0.06 | 0.04 | blup | 140 | 0.03 | 9.6e-05 | -4.5 | 5.2 | 2.0e-07 | -0.64 | 0.46 | 0.38 | FALSE |