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chr3:153,142,317-154,733,231

Best TWAS P=4.66e-13 · Best GWAS P=1.28e-11 conditioned to 0.0522

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Ovary	ARHGEF26	0.14	0.03	enet	15	0.06	1.4e-02	6.3	7.2	4.7e-13	-0.76	0.06	0.55	TRUE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SGEF	0.04	0.04	enet	12	0.04	1.1e-05	-5.6	6.7	2.4e-11	-0.77	0.09	0.88	FALSE
5	GTEx	Pancreas	ARHGEF26	0.26	0.26	lasso	5	0.28	3.2e-12	-5.5	6.6	4.1e-11	-0.73	0.66	0.34	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DHX36	0.05	0.06	blup	357	0.05	1.3e-06	-5.8	-6.5	9.4e-11	0.66	0.65	0.35	FALSE
9	GTEx	Thyroid	ARHGEF26	0.09	0.07	enet	17	0.08	1.9e-06	-5.7	6.5	1.1e-10	-0.62	0.34	0.63	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	ARHGEF26	0.13	0.11	lasso	4	0.07	6.8e-05	-5.5	6.3	2.4e-10	-0.70	0.28	0.71	FALSE
2	GTEx	Adipose Subcutaneous	ARHGEF26	0.10	0.06	enet	8	0.07	2.2e-06	-5.8	6.0	1.5e-09	-0.61	0.61	0.38	FALSE
8	GTEx	Spleen	DHX36	0.39	0.09	enet	21	0.34	2.1e-09	-3.5	-6.0	2.2e-09	0.66	0.41	0.55	FALSE
10	METSIM	Adipose	ARHGEF26	0.07	0.08	lasso	6	0.07	3.5e-11	-5.8	5.8	5.2e-09	-0.55	0.70	0.30	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	DHX36	0.11	0.09	enet	11	0.10	6.4e-12	-5.0	-5.6	2.6e-08	0.48	0.97	0.02	FALSE
3	GTEx	Artery Tibial	ARHGEF26	0.11	0.12	enet	12	0.12	5.9e-10	-5.8	5.5	4.0e-08	-0.54	0.74	0.26	FALSE
7	GTEx	Skin Sun Exposed Lower leg	ARHGEF26	0.10	0.08	enet	12	0.11	2.9e-09	-5.8	5.4	8.1e-08	-0.50	0.76	0.24	FALSE
13	The Cancer Genome Atlas	Soft Tissue Sarcoma	DHX36	0.05	0.00	enet	9	0.01	1.0e-01	-3.9	-5.2	1.7e-07	0.58	0.01	0.62	FALSE