Best TWAS P=4.47e-09 · Best GWAS P=4.32e-10 conditioned to 0.000303
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hippocampus | CRIPAK | 0.48 | 0.22 | lasso | 4 | 0.23 | 4.0e-06 | -3.1 | -5.1 | 2.8e-07 | 0.00 | 0.18 | 0.15 | FALSE |
| 2 | GTEx | Colon Transverse | TMEM129 | 0.23 | 0.05 | lasso | 4 | 0.03 | 1.8e-02 | -4.3 | 5.2 | 1.5e-07 | 0.51 | 0.09 | 0.09 | TRUE |
| 3 | GTEx | Lung | CRIPAK | 0.61 | 0.22 | enet | 46 | 0.41 | 1.1e-33 | -3.4 | -5.4 | 6.4e-08 | 0.02 | 1.00 | 0.00 | FALSE |
| 4 | GTEx | Nerve Tibial | CRIPAK | 0.50 | 0.11 | enet | 76 | 0.38 | 1.1e-28 | -3.1 | -5.9 | 4.5e-09 | -0.08 | 1.00 | 0.00 | TRUE |
| 5 | NTR | Blood | CRIPAK | 0.13 | 0.09 | enet | 31 | 0.15 | 1.5e-46 | -2.2 | -5.4 | 7.1e-08 | 0.00 | 1.00 | 0.00 | FALSE |