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chr4:17,104,059-18,507,692

Best TWAS P=1.26e-15 · Best GWAS P=4.54e-15 conditioned to 0.000176

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-7.3	8.0	1.3e-15	0.61	0.09	0.64	TRUE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	4.9	7.2	6.3e-13	0.72	0.05	0.87	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-6.9	-6.9	6.7e-12	-0.23	0.02	0.72	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	4.7	6.8	7.3e-12	0.68	0.14	0.78	FALSE
7	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	4.0	6.8	1.5e-11	0.73	0.03	0.78	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-6.8	-6.6	3.3e-11	-0.18	0.06	0.94	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-6.8	6.6	3.7e-11	0.28	0.16	0.45	FALSE
9	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	4.0	6.3	2.4e-10	0.78	0.03	0.94	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	-6.9	-6.2	6.0e-10	0.02	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	4.0	6.1	1.0e-09	0.72	0.27	0.24	FALSE
5	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-6.7	6.0	1.7e-09	0.50	0.06	0.40	FALSE
8	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	4.7	5.7	1.0e-08	0.90	0.02	0.90	FALSE
4	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	4.0	5.7	1.5e-08	0.71	0.13	0.68	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	DCAF16	0.16	0.08	lasso	5	0.12	4.4e-07	5.3	5.7	1.5e-08	0.75	0.33	0.51	FALSE
3	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	4.9	5.6	2.3e-08	0.84	0.06	0.94	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-5.8	-5.4	6.0e-08	-0.03	0.03	0.43	FALSE
1	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	4.0	5.1	2.8e-07	0.59	0.18	0.67	FALSE