Best TWAS P=4.96e-14 · Best GWAS P=4.07e-19 conditioned to 9.86e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | DNAJC18 | 0.17 | 0.01 | lasso | 10 | 0.04 | 2.0e-02 | 2.5 | 6.4 | 1.2e-10 | 0.77 | 0.03 | 0.85 | FALSE |
| 2 | GTEx | Esophagus Mucosa | TMEM173 | 0.10 | 0.03 | enet | 20 | 0.10 | 1.8e-07 | 8.9 | -5.4 | 6.3e-08 | -0.60 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Nerve Tibial | HARS | 0.07 | 0.01 | enet | 16 | 0.04 | 1.1e-03 | -4.3 | 5.2 | 1.6e-07 | -0.03 | 0.08 | 0.81 | FALSE |
| 4 | GTEx | Vagina | PURA | 0.52 | 0.05 | enet | 51 | 0.09 | 3.6e-03 | 6.2 | -6.6 | 3.6e-11 | -0.44 | 0.06 | 0.11 | FALSE |
| 5 | YFS | Blood | CXXC5 | 0.01 | 0.00 | bslmm | 244 | 0.01 | 2.6e-03 | 8.9 | -7.5 | 5.0e-14 | -0.67 | 0.00 | 0.95 | TRUE |
| 6 | YFS | Blood | TMCO6 | 0.01 | 0.00 | blup | 329 | 0.01 | 4.1e-03 | -4.5 | -5.3 | 1.2e-07 | -0.03 | 0.09 | 0.86 | FALSE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | WDR55 | 0.10 | 0.03 | enet | 8 | 0.04 | 3.3e-09 | -4.7 | -5.3 | 1.2e-07 | 0.01 | 0.02 | 0.96 | FALSE |
| 8 | The Cancer Genome Atlas | Colon Adenocarcinoma | WDR55 | 0.09 | 0.08 | enet | 12 | 0.12 | 1.5e-07 | -4.6 | -5.4 | 5.3e-08 | -0.05 | 0.02 | 0.95 | TRUE |
| 9 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | UBE2D2 | 0.05 | 0.02 | enet | 6 | 0.03 | 4.4e-04 | 4.0 | 6.8 | 1.1e-11 | 0.76 | 0.02 | 0.94 | FALSE |
| 10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | WDR55 | 0.07 | 0.06 | blup | 44 | 0.06 | 1.7e-06 | -4.7 | -5.2 | 2.6e-07 | -0.05 | 0.02 | 0.96 | FALSE |