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chr6:160,071,844-161,571,560

Best TWAS P=2.53e-12 · Best GWAS P=1.8e-14 conditioned to 3.2e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Caudate basal ganglia	SLC22A3	0.15	0.10	enet	39	0.11	5.6e-04	-6.4	-7.0	2.5e-12	0.64	0.23	0.44	TRUE
7	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A3	0.15	0.05	lasso	9	0.05	9.9e-04	-4.4	-6.5	1.2e-10	0.82	0.02	0.98	FALSE
5	GTEx	Nerve Tibial	SLC22A3	0.20	0.10	lasso	7	0.13	3.2e-09	-5.6	-5.9	2.9e-09	0.54	0.99	0.00	FALSE
3	GTEx	Brain Frontal Cortex BA9	SLC22A3	0.26	0.08	lasso	6	0.05	1.5e-02	-4.6	-5.9	3.1e-09	0.62	0.10	0.71	FALSE
4	GTEx	Esophagus Mucosa	SLC22A3	0.19	0.08	enet	47	0.12	1.7e-08	5.9	-5.8	8.1e-09	0.60	0.32	0.68	FALSE
8	GTEx	Skin Sun Exposed Lower leg	SLC22A3	0.29	0.14	lasso	10	0.20	3.7e-16	3.8	-5.7	9.6e-09	0.52	1.00	0.00	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	SLC22A3	0.14	0.20	lasso	10	0.19	2.4e-24	-5.2	-5.6	2.0e-08	0.61	1.00	0.00	FALSE
1	GTEx	Adipose Visceral Omentum	SLC22A3	0.13	0.06	enet	7	0.09	1.3e-05	-5.4	-5.4	5.8e-08	0.58	0.88	0.10	FALSE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LPAL2	0.07	0.00	blup	74	0.04	1.1e-03	-3.8	5.3	1.5e-07	-0.61	0.04	0.54	FALSE
6	GTEx	Ovary	SLC22A3	0.33	0.29	lasso	6	0.23	2.8e-06	-4.9	-5.1	3.0e-07	0.58	0.38	0.35	FALSE