[Hub]/) : Traits : Weight : ← →

chr6:160,071,844-161,571,560

Best TWAS P=2.53e-12 · Best GWAS P=1.8e-14 conditioned to 3.2e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum SLC22A3 0.13 0.06 enet 7 0.09 1.3e-05 -5.4 -5.4 5.8e-08 0.58 0.88 0.10 FALSE
2 GTEx Brain Caudate basal ganglia SLC22A3 0.15 0.10 enet 39 0.11 5.6e-04 -6.4 -7.0 2.5e-12 0.64 0.23 0.44 TRUE
3 GTEx Brain Frontal Cortex BA9 SLC22A3 0.26 0.08 lasso 6 0.05 1.5e-02 -4.6 -5.9 3.1e-09 0.62 0.10 0.71 FALSE
4 GTEx Esophagus Mucosa SLC22A3 0.19 0.08 enet 47 0.12 1.7e-08 5.9 -5.8 8.1e-09 0.60 0.32 0.68 FALSE
5 GTEx Nerve Tibial SLC22A3 0.20 0.10 lasso 7 0.13 3.2e-09 -5.6 -5.9 2.9e-09 0.54 0.99 0.00 FALSE
6 GTEx Ovary SLC22A3 0.33 0.29 lasso 6 0.23 2.8e-06 -4.9 -5.1 3.0e-07 0.58 0.38 0.35 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic SLC22A3 0.15 0.05 lasso 9 0.05 9.9e-04 -4.4 -6.5 1.2e-10 0.82 0.02 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg SLC22A3 0.29 0.14 lasso 10 0.20 3.7e-16 3.8 -5.7 9.6e-09 0.52 1.00 0.00 FALSE
9 ROSMAP Brain Pre-frontal Cortex SLC22A3 0.14 0.20 lasso 10 0.19 2.4e-24 -5.2 -5.6 2.0e-08 0.61 1.00 0.00 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LPAL2 0.07 0.00 blup 74 0.04 1.1e-03 -3.8 5.3 1.5e-07 -0.61 0.04 0.54 FALSE