Best TWAS P=1.94e-11 · Best GWAS P=6.32e-11 conditioned to 0.0231
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | AC004453.8 | 0.54 | 0.13 | lasso | 7 | 0.16 | 1.8e-04 | -1.8 | -5.2 | 2.4e-07 | 0.61 | 0.03 | 0.5 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PPIA | 0.05 | 0.02 | enet | 5 | 0.03 | 7.7e-05 | -6.3 | -6.7 | 1.9e-11 | 0.75 | 0.00 | 0.9 | TRUE |