Best TWAS P=4.39e-08 · Best GWAS P=1.86e-08 conditioned to 0.167
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | C6orf106 | 0.11 | 0.07 | enet | 17 | 0.07 | 1.3e-05 | 5.6 | 5.2 | 2.6e-07 | 0.87 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Uterus | UHRF1BP1 | 0.20 | 0.03 | lasso | 4 | 0.07 | 1.8e-02 | 4.4 | 5.3 | 1.3e-07 | 0.72 | 0.08 | 0.32 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C6orf106 | 0.04 | 0.05 | lasso | 4 | 0.03 | 8.1e-05 | 5.5 | 5.5 | 4.4e-08 | 0.95 | 0.01 | 0.99 | TRUE |