TWAS
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chr7:1,161,158-2,972,072
Best TWAS P=2.76e-10 · Best GWAS P=8.37e-12 conditioned to 4.48e-05
1.5M
2M
2.5M
3M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
MAD1L1
0.09
0.01
blup
206
0.04
0.00011
5.9
-6.3
2.8e-10
0.54
0.06
0.56
TRUE
1
GTEx
Whole Blood
MAD1L1
0.15
0.01
enet
21
0.03
0.00135
6.2
5.1
2.7e-07
-0.45
0.16
0.72
FALSE