Best TWAS P=2.13e-07 · Best GWAS P=3.75e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | SEMA4A | 0.20 | 0.17 | lasso | 3 | 0.16 | 9.4e-09 | 5.1 | 5.1 | 2.7e-07 | 1.00 | 0 | 1 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | SEMA4A | 0.51 | 0.36 | enet | 3 | 0.39 | 3.7e-34 | 5.1 | 5.1 | 2.9e-07 | 0.99 | 0 | 1 | FALSE |
| 3 | GTEx | Thyroid | SEMA4A | 0.48 | 0.31 | lasso | 5 | 0.30 | 5.8e-23 | 5.1 | 5.2 | 2.1e-07 | 1.00 | 0 | 1 | TRUE |
| 4 | GTEx | Whole Blood | SEMA4A | 0.10 | 0.13 | enet | 3 | 0.13 | 3.7e-12 | 5.0 | 5.1 | 3.1e-07 | 1.00 | 0 | 1 | FALSE |