Best TWAS P=3.08e-08 · Best GWAS P=2.55e-08 conditioned to 0.232
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | B3GALTL | 0.25 | 0.19 | lasso | 6 | 0.26 | 1.8e-17 | -5.2 | -5.2 | 2.3e-07 | 0.88 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | B3GALTL | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.5e-04 | -5.2 | -5.5 | 3.1e-08 | 0.92 | 0.00 | 0.99 | TRUE |