Best TWAS P=5.07e-09 · Best GWAS P=3.36e-09 conditioned to 0.0522
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | GALNT16 | 0.26 | 0.04 | lasso | 7 | 0.04 | 0.033 | 4.4 | 5.6 | 1.6e-08 | -0.64 | 0.04 | 0.65 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DCAF5 | 0.04 | 0.01 | blup | 77 | 0.01 | 0.027 | -4.4 | 5.8 | 5.1e-09 | -0.82 | 0.02 | 0.50 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ACTN1 | 0.06 | 0.00 | blup | 134 | 0.01 | 0.011 | -4.4 | 5.1 | 2.8e-07 | -0.53 | 0.02 | 0.49 | FALSE |