Best TWAS P=2.96e-08 · Best GWAS P=8.75e-08 conditioned to 0.552
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | METSIM | Adipose | PHLPP2 | 0.07 | 0.03 | lasso | 5 | 0.06 | 1.7e-09 | 5.1 | 5.5 | 3.0e-08 | 0.92 | 0.04 | 0.96 | TRUE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PHLPP2 | 0.11 | 0.03 | lasso | 6 | 0.01 | 1.2e-01 | 4.9 | 5.5 | 3.2e-08 | 0.90 | 0.02 | 0.56 | FALSE |
| 4 | YFS | Blood | PHLPP2 | 0.04 | 0.03 | bslmm | 459 | 0.05 | 5.5e-16 | -4.2 | 5.5 | 4.0e-08 | 0.81 | 0.48 | 0.45 | FALSE |
| 1 | GTEx | Thyroid | RP11-432I5.6 | 0.07 | 0.07 | enet | 11 | 0.05 | 1.2e-04 | 5.1 | 5.5 | 5.0e-08 | 0.93 | 0.02 | 0.97 | FALSE |
| 3 | YFS | Blood | ATXN1L | 0.02 | 0.02 | blup | 413 | 0.02 | 6.5e-07 | 3.7 | 5.3 | 1.4e-07 | 0.74 | 0.29 | 0.67 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PHLPP2 | 0.20 | 0.08 | blup | 67 | 0.14 | 1.4e-13 | 4.6 | 5.1 | 2.8e-07 | 0.76 | 0.02 | 0.96 | FALSE |