Best TWAS P=2.88e-08 · Best GWAS P=2.41e-08 conditioned to 0.222
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GCC2 | 0.12 | 0.17 | enet | 30 | 0.18 | 5.1e-21 | 5.5 | 5.5 | 2.9e-08 | 0.92 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Brain Cerebellum | GCC2 | 0.17 | 0.10 | enet | 16 | 0.08 | 2.4e-03 | 4.9 | 5.3 | 9.3e-08 | 0.94 | 0.02 | 0.94 | FALSE |
| 3 | GTEx | Esophagus Muscularis | LIMS1 | 0.10 | 0.00 | lasso | 3 | 0.00 | 2.4e-01 | 5.2 | 5.2 | 1.8e-07 | 0.88 | 0.03 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LIMS1 | 0.02 | 0.01 | blup | 54 | 0.02 | 4.1e-03 | -4.1 | -5.2 | 1.8e-07 | -0.88 | 0.03 | 0.79 | FALSE |