Best TWAS P=5.42e-13 · Best GWAS P=1.35e-14 conditioned to 0.00674
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | ZNF318 | 0.04 | 0.03 | lasso | 8 | 0.02 | 1.3e-08 | -6.9 | -7.2 | 5.4e-13 | 0.94 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CRIP3 | 0.08 | 0.08 | blup | 34 | 0.07 | 1.0e-04 | -7.7 | -6.9 | 5.5e-12 | 0.95 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF318 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.1e-06 | -5.2 | 5.3 | 9.2e-08 | -0.72 | 0.84 | 0.07 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZNF318 | 0.04 | 0.02 | blup | 48 | 0.04 | 2.2e-03 | -7.7 | -7.2 | 6.1e-13 | 0.93 | 0.01 | 0.80 | FALSE |