38 significantly associated models · 20 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 45393277 | 46782409 | 1 | 1 | 2.5e-07 | 1.4e-06 | 0.3400 | 96 | CCDC17 |
2 | 2 | 42753863 | 44149442 | 1 | 1 | 6.9e-08 | 1.7e-05 | 0.1850 | 90 | ZFP36L2 |
3 | 5 | 72162264 | 73934274 | 4 | 7 | 2.9e-16 | 1.4e-19 | NaN | NaN | ANKRA2 ARHGEF28 RGNEF UTP15 |
4 | 5 | 147825590 | 149338157 | 1 | 1 | 6.0e-08 | 2.1e-07 | 1.0000 | 100 | ABLIM3 |
5 | 6 | 42611872 | 44034691 | 2 | 1 | 5.4e-13 | 1.3e-14 | 0.0067 | 88 | ZNF318 |
6 | 8 | 140969818 | 142706843 | 1 | 1 | 7.3e-08 | 6.4e-08 | 0.0159 | 80 | PTK2 |
7 | 10 | 75189586 | 76603535 | 1 | 1 | 9.0e-08 | 5.5e-06 | 0.4600 | 97 | AP3M1 |
8 | 11 | 117732806 | 119353188 | 4 | 1 | 9.0e-11 | 3.0e-10 | 1.0000 | 100 | DDX6 |
9 | 12 | 109295508 | 110704487 | 1 | 1 | 5.4e-08 | 3.1e-07 | 1.0000 | 100 | MMAB |
10 | 17 | 6469505 | 7863344 | 1 | 1 | 2.9e-07 | 1.2e-06 | 0.1440 | 91 | CLDN7 |
11 | 18 | 52324675 | 52873317 | 1 | 1 | 9.4e-08 | 4.0e-08 | 0.0961 | 91 | CCDC68 |
12 | 19 | 19391402 | 19892796 | 1 | 1 | 1.1e-07 | 3.2e-06 | 0.2010 | 92 | YJEFN3 |
13 | 19 | 52150601 | 52657049 | 1 | 1 | 3.1e-07 | 1.4e-04 | 0.1910 | 88 | ZNF649 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Thyroid | 0 | 0.000 | 1.7 |
GTEx | Uterus | 0 | 0.000 | 1.7 |
GTEx | Adipose Subcutaneous | 2 | 0.057 | 1.6 |
GTEx | Adipose Visceral Omentum | 1 | 0.049 | 1.6 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.6 |
GTEx | Artery Coronary | 0 | 0.000 | 1.6 |
GTEx | Brain Cerebellum | 1 | 0.050 | 1.6 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.6 |
GTEx | Breast Mammary Tissue | 1 | 0.051 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.6 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.6 |
GTEx | Colon Transverse | 0 | 0.000 | 1.6 |
GTEx | Esophagus Mucosa | 2 | 0.060 | 1.6 |
GTEx | Esophagus Muscularis | 0 | 0.000 | 1.6 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.6 |
GTEx | Lung | 0 | 0.000 | 1.6 |
GTEx | Muscle Skeletal | 0 | 0.000 | 1.6 |
GTEx | Nerve Tibial | 1 | 0.023 | 1.6 |
GTEx | Pancreas | 1 | 0.061 | 1.6 |
GTEx | Pituitary | 0 | 0.000 | 1.6 |
GTEx | Skin Not Sun Exposed Suprapubic | 0 | 0.000 | 1.6 |
GTEx | Skin Sun Exposed Lower leg | 0 | 0.000 | 1.6 |
GTEx | Spleen | 0 | 0.000 | 1.6 |
GTEx | Testis | 0 | 0.000 | 1.6 |
GTEx | Whole Blood | 0 | 0.000 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 2 | 0.046 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.090 | 1.6 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.063 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 1 | 0.075 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.094 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 0 | 0.000 | 1.6 |
GTEx | Artery Aorta | 0 | 0.000 | 1.5 |
GTEx | Artery Tibial | 1 | 0.027 | 1.5 |
GTEx | Brain Caudate basal ganglia | 1 | 0.109 | 1.5 |
GTEx | Brain Cerebellar Hemisphere | 0 | 0.000 | 1.5 |
GTEx | Brain Cortex | 1 | 0.097 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.5 |
GTEx | Cells Transformed fibroblasts | 1 | 0.024 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.5 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.5 |
GTEx | Liver | 1 | 0.139 | 1.5 |
GTEx | Ovary | 0 | 0.000 | 1.5 |
GTEx | Prostate | 0 | 0.000 | 1.5 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.5 |
GTEx | Stomach | 0 | 0.000 | 1.5 |
METSIM | Adipose | 1 | 0.022 | 1.5 |
NTR | Blood | 1 | 0.042 | 1.5 |
YFS | Blood | 1 | 0.022 | 1.5 |
CommonMind | Brain Pre-frontal Cortex | 2 | 0.037 | 1.5 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 1 | 0.049 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 2 | 0.046 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 3 | 0.065 | 1.5 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.145 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 1 | 0.019 | 1.5 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.5 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.4 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.4 |
GTEx | Vagina | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 1 | 0.023 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.4 |